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Functional mapping of fish social brain

Research Project

Project/Area Number 26290003
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypePartial Multi-year Fund
Section一般
Research Field Neurophysiology / General neuroscience
Research InstitutionOkayama University (2015-2016)
The University of Tokyo (2014)

Principal Investigator

Takeuchi Hideaki  岡山大学, 自然科学研究科, 准教授 (00376534)

Co-Investigator(Kenkyū-buntansha) 久保 健雄  東京大学, 理学(系)研究科(研究院), 教授 (10201469)
横井 佐織  北海道大学, 薬学研究科(研究院), 助教 (10772048)
Co-Investigator(Renkei-kenkyūsha) KAMEI Yasuhiro  基礎生物学研究所, 生物機能解析センター, 特任准教授 (70372563)
Research Collaborator Isoe Yasuko  岡山大学, 大学院自然科学研究科, 助教(特別契約職員) (60786119)
Project Period (FY) 2014-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥16,640,000 (Direct Cost: ¥12,800,000、Indirect Cost: ¥3,840,000)
Fiscal Year 2016: ¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2015: ¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2014: ¥5,980,000 (Direct Cost: ¥4,600,000、Indirect Cost: ¥1,380,000)
Keywords硬骨魚類 / 神経ペプチド / 社会行動 / ゲノム編集 / 配偶者選択 / 個体認知 / オキシトシン / 神経科学 / 脳・神経 / 遺伝子 / 行動発達 / 脳機能地図 / 行動学 / 生態学 / 社会性行動 / メダカ / ホルモン / バソトシン / 社会脳 / 小型魚類 / 条件的遺伝子操作法 / IR-LEGO
Outline of Final Research Achievements

Male medaka fish in a triad relationship (two males and one female) hold a position between the rival male and a female (mate-guarding), which results in improvement of mating success. Behavioral analysis of mutant males revealed that vasotocin system is required for dominance in mate-guarding (PLoS Genetics 2015). Our study also suggested mate-guarding behavior has an effect on visual familiarity and female mate preference. Previously we found that female medaka prefer to mate with visually-familiarized males (Science 2014). We showed that mate-guarding behaviors blocked visual familiarization of a female with the rival in a triad relationship, suggesting that female mate preference for familiar mates may help ascertain social dominance in males(Frontiers in Zoology, 2016).

Report

(4 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Annual Research Report
  • 2014 Annual Research Report
  • Research Products

    (33 results)

All 2017 2016 2015 2014 Other

All Int'l Joint Research (2 results) Journal Article (6 results) (of which Int'l Joint Research: 3 results,  Peer Reviewed: 6 results,  Open Access: 4 results,  Acknowledgement Compliant: 5 results) Presentation (17 results) (of which Int'l Joint Research: 4 results,  Invited: 9 results) Book (3 results) Remarks (5 results)

  • [Int'l Joint Research] エモリー大学(米国)

    • Related Report
      2016 Annual Research Report
  • [Int'l Joint Research] Emory University(米国)

    • Related Report
      2015 Annual Research Report
  • [Journal Article] Mate-guarding behavior enhances male reproductive success via familiarization with mating partners in medaka fish.2016

    • Author(s)
      Yokoi S, Ansai S, Kinoshita M, Naruse K, Kamei Y, Young LJ, Okuyama T, Takeuchi H.
    • Journal Title

      Frontiers in Zoology

      Volume: 13 Issue: 1 Pages: 21-21

    • DOI

      10.1186/s12983-016-0152-2

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Ontogeny and sexual differences in swimming proximity to conspecifics in response to visual cues in medaka fish2016

    • Author(s)
      Y. Isoe, Y. Konagaya, S. Yokoi, T. Kubo, H. Takeuchi
    • Journal Title

      Zool. Sci.

      Volume: 33 Issue: 3 Pages: 246-246

    • DOI

      10.2108/zs150213

    • NAID

      210000176073

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Ontogeny and sexual differences in swimming proximity to conspecifics in response to visual cues in medaka fish2016

    • Author(s)
      Yasuko Isoe, Yumi Konagaya, Saori Yokoi, Takeo Kubo, Hideaki Takeuchi
    • Journal Title

      Zoological Science

      Volume: XXX

    • NAID

      210000176073

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Mate-guarding behavior enhances male reproductive success via familiarization with mating partners in medaka fish2016

    • Author(s)
      Saori Yokoi, Ansai Satoshi, Masato Kinoshita, Kiyoshi Naruse, LarryJ Young, Teruhiro Okuyama and Hideaki Takeuchi
    • Journal Title

      Frontiers in Zoology

      Volume: XXX

    • NAID

      120006331985

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] An Essential Role of the Arginine Vasotocin System in Mate-Guarding Behaviors in Triadic Relationships of Medaka Fish (Oryzias latipes).2015

    • Author(s)
      Yokoi S, Okuyama T, Kamei Y, Naruse K, Taniguchi Y, Ansai S, Kinoshita M, Young LJ, Takemori N, Kubo T, Takeuchi H
    • Journal Title

      PLoS Genetics

      Volume: なし Issue: 2 Pages: e1005009-e1005009

    • DOI

      10.1371/journal.pgen.1005009

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Genetic control of startle behavior in medaka fish2014

    • Author(s)
      Tsuboko S, Kimura T, Shinya M, Suehiro Y, Okuyama T, Shimada A, Takeda H, Naruse K, Kubo T, Takeuchi H
    • Journal Title

      PLoS one

      Volume: 9 Issue: 11 Pages: e112527-e112527

    • DOI

      10.1371/journal.pone.0112527

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Presentation] メダカの三角関係の分子神経基盤2017

    • Author(s)
      竹内秀明
    • Organizer
      I―URIC フロンティアコロキウム
    • Place of Presentation
      ホテルアソシア静岡
    • Year and Date
      2017-03-02
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] 三角関係(オス、オス、メス)においてライバルへのメスの目移りを防ぐオスメダカ)2016

    • Author(s)
      横井佐織、竹内秀明
    • Organizer
      第26回日本行動神経内分泌研究会
    • Place of Presentation
      ホテル・サンミ倶楽部
    • Year and Date
      2016-04-28
    • Related Report
      2016 Annual Research Report
  • [Presentation] Exploring the neural geography of the social brain using medaka fish2016

    • Author(s)
      Hideaki Takeuchi (Keynote lecture)
    • Organizer
      17th Australia & New Zealand Zebrafish Meeting
    • Place of Presentation
      Flinders, Australia
    • Year and Date
      2016-02-03
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Exploring the neural geography of the social brain using medaka fish2016

    • Author(s)
      Hideaki Takeuchi (Keynote lecture)
    • Organizer
      3rd Medaka Strategic Meeting
    • Place of Presentation
      Flinders, Australia
    • Year and Date
      2016-02-01
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] メダカの個体認知を介した社会行動の神経機構」2016

    • Author(s)
      竹内秀明
    • Organizer
      日本神経科学学会
    • Place of Presentation
      横浜
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] メダカの恋の三角関係の神経分子基盤2016

    • Author(s)
      竹内秀明
    • Organizer
      OCUテニュアトラック研究集会
    • Place of Presentation
      大阪市立大学
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] メダカを用いた個体記憶を介した社会的意思決定機構の解明2015

    • Author(s)
      竹内秀明
    • Organizer
      共感性領域・自己制御精神領域合同シンポジウム・個体と社会の関係を科学する
    • Place of Presentation
      東京
    • Year and Date
      2015-12-19
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] Neural mechanism of female preference mediated by social memory2015

    • Author(s)
      Hideaki Takeuchi
    • Organizer
      Symposium on Memory and Mind, Tohoku Forum for Creativity
    • Place of Presentation
      仙台
    • Year and Date
      2015-09-28
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] メダカの三角関係を生み出す分子基盤2015

    • Author(s)
      竹内秀明
    • Organizer
      日本動物学会関東支部公開講演会「動物の行動を科学する」
    • Place of Presentation
      東京
    • Year and Date
      2015-08-01
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] Analysis of mechanism underlying brain growth accompanied by neurogenesis using medaka fish (Oryzias latipes)2014

    • Author(s)
      Yasuko Isoe, Teruhiro Okuyama, Masahito Hoki, Yuji Suehiro, Genki Yamagishi,Kiyoshi Naruse, Masato Kinoshita, Yasuhiro Kamei, Shigenori Nonaka Atushi Shimizu, Takeo Kubo, Hideaki Takeuchi
    • Organizer
      Neuroscience 2014/ SfN(北米神経学会)
    • Place of Presentation
      アメリカ・ワシントンD.C.
    • Year and Date
      2014-11-17
    • Related Report
      2014 Annual Research Report
  • [Presentation] Analysis of mechanism underlying brain growth accompanied by neurogenesis using medaka fish (Oryzias latipes)2014

    • Author(s)
      Yasuko Isoe, Teruhiro Okuyama, Masahito Hoki, Yuji Suehiro, Genki Yamagishi,Kiyoshi Naruse, Masato Kinoshita, Yasuhiro Kamei, Shigenori Nonaka Atushi Shimizu, Takeo Kubo, Hideaki Takeuchi
    • Organizer
      Neuro2014 / The 36th Annual Meeting of the Japan Neuroscience Society
    • Place of Presentation
      名古屋
    • Year and Date
      2014-09-09
    • Related Report
      2014 Annual Research Report
  • [Presentation] Analysis of mechanism underlying brain growth accompanied by neurogenesis using medaka fish (Oryzias latipes)2014

    • Author(s)
      Yasuko Isoe, Teruhiro Okuyama, Masahito Hoki, Yuji Suehiro, Genki Yamagishi,Kiyoshi Naruse, Masato Kinoshita, Yasuhiro Kamei, Shigenori Nonaka Atushi Shimizu, Takeo Kubo, Hideaki Takeuchi
    • Organizer
      2014 International Congress of Neuroethology/The Japanese Society for comparative Physiology and Biochemistry
    • Place of Presentation
      札幌
    • Year and Date
      2014-07-29
    • Related Report
      2014 Annual Research Report
  • [Presentation] Searching for genes affecting visually-evoked startle response properties with inbred strains of Medaka (Oryzias latipes) -- Genetically Affected Escape Modes in Solitary and Collective States of Medaka Fish2014

    • Author(s)
      坪子理美、木村哲晃 、新屋みのり、末廣勇司、奥山輝大、島田敦子、武田洋幸、成瀬清、久保健雄、竹内秀明
    • Organizer
      2014 International Congress of Neuroethology/The Japanese Society for comparative Physiology and Biochemistry
    • Place of Presentation
      札幌
    • Year and Date
      2014-07-28
    • Related Report
      2014 Annual Research Report
  • [Presentation] Analysis of mechanism underlying brain growth accompanied by neurogenesis using medaka fish (Oryzias latipes)2014

    • Author(s)
      Yasuko Isoe, Teruhiro Okuyama, Masahito Hoki, Yuji Suehiro, Genki Yamagishi,Kiyoshi Naruse, Masato Kinoshita, Yasuhiro Kamei, Shigenori Nonaka Atushi Shimizu, Takeo Kubo, Hideaki Takeuchi
    • Organizer
      2nd Strategic Meeting for Medaka Research
    • Place of Presentation
      スペイン・セビリア
    • Year and Date
      2014-04-11
    • Related Report
      2014 Annual Research Report
  • [Presentation] Searching for genes affecting visually-evoked startle response properties with medaka inbred strains2014

    • Author(s)
      坪子理美、木村哲晃 、新屋みのり、末廣勇司、奥山輝大、島田敦子、武田洋幸、成瀬清、久保健雄、竹内秀明
    • Organizer
      2nd Strategic Meeting for Medaka Research
    • Place of Presentation
      セビリア・スペイン
    • Year and Date
      2014-04-10 – 2014-04-12
    • Related Report
      2014 Annual Research Report
  • [Presentation] Behavioral polymorphism in medaka strains: genetic factor matters?2014

    • Author(s)
      Mu-Yun Wang, Takeo Kubo and Hideaki Takeuchi
    • Organizer
      2nd Strategic Meeting for Medaka Research
    • Place of Presentation
      セビリア・スペイン
    • Year and Date
      2014-04-10 – 2014-04-12
    • Related Report
      2014 Annual Research Report
  • [Presentation] Proximate and ultimate causes of socially-regulated mating preference in medaka fish2014

    • Author(s)
      Hideaki Takeuchi
    • Organizer
      2nd Strategic Meeting for Medaka Research
    • Place of Presentation
      スペイン・セビリア
    • Year and Date
      2014-04-10
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Book] 「社会的記憶“異性の好み”を生み出す神経機構」生体の科学2016

    • Author(s)
      竹内秀明
    • Total Pages
      4
    • Publisher
      医学書院
    • Related Report
      2016 Annual Research Report
  • [Book] 「メダカを用いた“魚類社会脳”の 分子神経基盤の解明」ブレインサイエンス・レビュー20172016

    • Author(s)
      竹内秀明
    • Total Pages
      20
    • Publisher
      クバプロ
    • Related Report
      2016 Annual Research Report
  • [Book] 新・生命科学シリーズ 動物行動の分子生物学2014

    • Author(s)
      竹内秀明
    • Total Pages
      27
    • Publisher
      裳華房
    • Related Report
      2014 Annual Research Report
  • [Remarks] 岡山大学大学院自然科学研究科(理学部生物学科) 分子行動学研究室

    • URL

      https://sites.google.com/view/molecular-ethology-laboratory/%E3%83%9B%E3%83%BC%E3%83%A0

    • Related Report
      2016 Annual Research Report
  • [Remarks] Researchmap

    • URL

      http://researchmap.jp/Takeuchi/?lang=japanese

    • Related Report
      2016 Annual Research Report
  • [Remarks] Researchmap

    • URL

      http://researchmap.jp/takeuchi/?lang=japanese

    • Related Report
      2015 Annual Research Report
  • [Remarks] 恋敵からメスを守るオスメダカ

    • URL

      http://www.u-tokyo.ac.jp/ja/utokyo-research/research-news/stay-away-from-my-girl.html

    • Related Report
      2014 Annual Research Report
  • [Remarks] 恋敵からメスを守るオスメダカ

    • URL

      http://www.s.u-tokyo.ac.jp/ja/press/4154/

    • Related Report
      2014 Annual Research Report

URL: 

Published: 2014-04-04   Modified: 2023-03-23  

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