| Budget Amount *help |
¥16,900,000 (Direct Cost: ¥13,000,000、Indirect Cost: ¥3,900,000)
Fiscal Year 2016: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2015: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2014: ¥9,750,000 (Direct Cost: ¥7,500,000、Indirect Cost: ¥2,250,000)
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| Outline of Final Research Achievements |
In this study, we analyzed the molecular function of noncoding RNAs which regulate maintenance and differentiation of germline stem cells using Drosophila as a model organism. We identified wide-variety of long noncoding RNAs expressed only in germline stem cells, and we hope to elucidate their expression network. We also clarified the dynamics of small noncoding piRNA during spermatogenesis, and the role of heterochromatic protein 1 (HP1a) in piRNA biosynthesis during the subsidy period. These results would consolidate the basis for comprehensive understanding of germline-specific noncoding RNAs.
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