Analyses of chromatin interaction responsible for subnuclear dynamics
Project/Area Number |
26291067
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Research Category |
Grant-in-Aid for Scientific Research (B)
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Allocation Type | Partial Multi-year Fund |
Section | 一般 |
Research Field |
Morphology/Structure
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Research Institution | Tokyo University of Science |
Principal Investigator |
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Co-Investigator(Renkei-kenkyūsha) |
Sakamoto Takuya 東京理科大学, 理工学部, 助教 (40637691)
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Project Period (FY) |
2014-04-01 – 2017-03-31
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Project Status |
Completed (Fiscal Year 2016)
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Budget Amount *help |
¥15,080,000 (Direct Cost: ¥11,600,000、Indirect Cost: ¥3,480,000)
Fiscal Year 2016: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2015: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2014: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
|
Keywords | クロマチン / 核内構造 / クロマチンリモデリング因子 / DNA損傷 / 核構造 / 環境 / 染色体 / 植物 |
Outline of Final Research Achievements |
The purpose of this project is to reveal the dynamics of chromatin in nuclei. We successfully performed four-dimensional live-cell imaging using lacO/LacI inserted visualization lines. Based on this system, we could get dynamic data of chromatin-interaction in the nucleus of living cells. We identified a chromatin remodeling protein RAD54 as a regulator responsible for chromatin interaction and revealed a part of molecular mechanism in subnuclear chromatin dynamics.
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Report
(4 results)
Research Products
(254 results)
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[Journal Article] Plant Aurora kinases interact with and phosphorylate transcription factors.2016
Author(s)
Takagi, M., Sakamoto, T.,Suzuki, R.,Nemoto, K., Obayashi, T., Matsunaga, T. M., Hirakawa, T., Kurihara, D., Nariai, Y., Urano, T., Sawasaki, T., Matsunaga, S.
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Journal Title
JOURNAL OF PLANT RESEARCH
Volume: 129
Issue: 6
Pages: 1165-1178
DOI
NAID
Related Report
Peer Reviewed / Open Access / Acknowledgement Compliant
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[Journal Article] Novel anticancer agent, SQAP, binds to focal adhesion kinase and modulates its activity.2015
Author(s)
Izaguirre-Carbonell, J., Kawakubo, H., Murata, H., Tanabe, A., Takeuchi, T., Kusayanagi, T., Tsukuda, S., Hirakawa, T., Iwabata, K., Kanai, Y., Ohta, K., Miura, M., Sakaguchi, K., Matsunaga, S., Sahara, H., Kamisuki, S., and Sugawara, F.
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Journal Title
Scientific Reports
Volume: 5
Issue: 1
Pages: 15136-15136
DOI
Related Report
Peer Reviewed / Open Access
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[Journal Article] Coherent X-ray diffraction imaging of chloroplasts from Cyanidioschyzon merolae by using X-ray free electron laser.2015
Author(s)
Takayama, Y., Inui, Y., Sekiguchi, Y., Kobayashi, A., Oroguchi, T., Yamamoto, M., Matsunaga, S., and Nakasako, M.
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Journal Title
PLANT AND CELL PHYSIOLOGY
Volume: 未定
Issue: 7
Pages: 1-15
DOI
Related Report
Peer Reviewed / Open Access
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[Presentation] Live imaging of epigenetic modifications in plant cells2017
Author(s)
Sachihiro Matsunaga、 Kazuki Kurita、 Noriyoshi Yagi、 Yuki Sakamoto、 Kaori Sako、 Takashi Murata、 Mitsuyasu Hasebe、 Hiroshi Kimura、 Motoaki Seki、Takuya Sakamoto
Organizer
International Symposium on Environmental Stress Adaptation & Memory in Plants
Place of Presentation
1F Hall, Main Office Building, RIKEN Yokohama Campus
Year and Date
2017-02-27
Related Report
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[Presentation] Nobel epigenetic, RNA and peptide regulation in plant abiotic stress responses2016
Author(s)
Jong-Myong Kim、Akihiro Matsui、Kentaro Nakaminami、Kaori Sako、Minoru Ueda、Taiko Kim To、Huong Mai Nguyen、Khurram Bashir、Sultana Rasheed、Junko Ishida、Maho Tanaka、Minoru Yoshida、Masanori Okamoto、Kousuke Hanada、Yoshiki Habu、Sachihiro Matsunaga
Organizer
Cold Spring Harbor Asia Conferences 2016
Place of Presentation
The Westin Resort and Conference Center Awaji Island、Hyogo、Japan
Year and Date
2016-12-02
Related Report
Int'l Joint Research / Invited
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[Presentation] コンデンシンIIによるセントロメア配置制御2016
Author(s)
山下 朋恵 , 坂本 卓也 , 坂本 勇貴 , 松井 章浩 , 金 鐘明 , 関 原明 , 松永 幸大
Organizer
日本植物形態学会第28回総会・大会
Place of Presentation
琉球大学千原キャンパス(沖縄県中頭郡)
Year and Date
2016-09-15
Related Report
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[Presentation] Cryogenic coherent diffraction imaging of biological samples with synchrotron and X-ray laser2016
Author(s)
Yuki Takayama, Masaki Yamamoto, Koji Yonekura, Yuki Sekiguchi, Amane Kobayashi, Koji Okajima, Tomotaka Oroguchi, Masayoshi Nakasako, Yayoi Inui, Sachihiro Matsunaga
Organizer
13th International Conference on X-ray Microscopy (XRM2016)
Place of Presentation
The Mathematical Institute, University of Oxford, UK
Year and Date
2016-08-18
Related Report
Int'l Joint Research
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[Presentation] 環境変化に伴う細胞内pHイメージング解析2015
Author(s)
栗田和貴, 坂本卓也, 金鍾明, 関原明, 松永幸大
Organizer
東京理科大学研究推進機構総合研究院イメージングフロンティアセンターシンポジウム
Place of Presentation
東京理科大学(千葉県野田市)
Year and Date
2015-12-25
Related Report
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[Presentation] Regulation of chromatin dynamics mediated by condensin II2015
Author(s)
Tomoe Yamashita, Takuya Sakamoto, Yuki Sakamoto, Akihiro Matsui, Jong-Myong Kim, Motoaki Seki, Sachihiro Matsunaga
Organizer
Towards Increased Plant Productivity through Understanding of Environmental Responses and Epigenetic Regulation
Place of Presentation
理化学研究所(神奈川県横浜市)
Year and Date
2015-11-24
Related Report
Int'l Joint Research
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[Presentation] Introduction of Live Imaging Center2015
Author(s)
Sachihiro Matsunaga, Minako Ueda
Organizer
The 1st Meeting of Young Scientists for Integrative System of Autonomous Environmental Signal Recognition and Memorization for Plant Plasticity
Place of Presentation
ウェルシーズン浜名湖(静岡県浜松市)
Year and Date
2015-11-19
Related Report
Int'l Joint Research
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[Presentation] Chromatin visualization with TALEs in Arabidopsis2015
Author(s)
Satoru Fujimoto, Shigeo Sugano, Keishi Osakabe, Sachihiro Matsunaga
Organizer
The 1st Meeting of Young Scientists for Integrative System of Autonomous Environmental Signal Recognition and Memorization for Plant Plasticity
Place of Presentation
ウェルシーズン浜名湖(静岡県浜松市)
Year and Date
2015-11-18
Related Report
Int'l Joint Research
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[Presentation] Analysis of CRWNs regulating nuclear shape in Arabidopsis thaliana2015
Author(s)
Yuki Sakamoto, Mayuko Sato, Kiminori Toyooka, Shingo Takagi, Sachihiro Matsunaga
Organizer
The 1st Meeting of Young Scientists for Integrative System of Autonomous Environmental Signal Recognition and Memorization for Plant Plasticity
Place of Presentation
ウェルシーズン浜名湖(静岡県浜松市)
Year and Date
2015-11-18
Related Report
Int'l Joint Research
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[Presentation] Substrate search of aurora kinase in Arabidopsis2015
Author(s)
Ritsuko Suzuki, Takuya Sakamoto, Mai Takagi, Keiichiro Nemoto, Tatsuya Sawazaki, Sachihiro Matsunaga
Organizer
The 1st Meeting of Young Scientists for Integrative System of Autonomous Environmental Signal Recognition and Memorization for Plant Plasticity
Place of Presentation
ウェルシーズン浜名湖(静岡県浜松市)
Year and Date
2015-11-18
Related Report
Int'l Joint Research
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[Presentation] Analysis of epigenetic factors involved in de novo shoot regeneration2015
Author(s)
Hiroya Ishihara, Kaoru Sugimoto, Takuya Sakamoto, Taku Sasaki, Motoaki Seki, Elliot Meyerowitz, Sachihiro Matsunaga
Organizer
The 1st Meeting of Young Scientists for Integrative System of Autonomous Environmental Signal Recognition and Memorization for Plant Plasticity
Place of Presentation
ウェルシーズン浜名湖(静岡県浜松市)
Year and Date
2015-11-18
Related Report
Int'l Joint Research
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[Presentation] Regulation of chromatin dynamics by condensin II2015
Author(s)
Tomoe Yamashita, Takuya Sakamoto, Yuki Sakamoto, Akihiro Matsui, Jong-Myong Kim, Motoaki Seki, Sachihiro Matsunaga
Organizer
The 1st Meeting of Young Scientists for Integrative System of Autonomous Environmental Signal Recognition and Memorization for Plant Plasticity
Place of Presentation
ウェルシーズン浜名湖(静岡県浜松市)
Year and Date
2015-11-18
Related Report
Int'l Joint Research
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[Presentation] Novel findings for molecular mechanisms of boron toxicity in plants2015
Author(s)
Takuya Sakamoto, Yayoi Inu-Tsujimotoi, Naoyuki Sotta, Masayuki Fujiwara, Yoichiro Fukao, Sachihiro Matsunaga, Toru Fujiwara
Organizer
The 1st Meeting of Young Scientists for Integrative System of Autonomous Environmental Signal Recognition and Memorization for Plant Plasticity
Place of Presentation
ウェルシーズン浜名湖(静岡県浜松市)
Year and Date
2015-11-18
Related Report
Int'l Joint Research
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[Presentation] Analysis of an epigenetic factor involved in cell proliferation of callus2015
Author(s)
Yuki Katsuyama, Kaoru Sugimoto, Junko Hasegawa, Kazuki Ishibashi, Jung-Myong Kim, Motoaki Seki, Sachihiro Matsunaga
Organizer
The 1st Meeting of Young Scientists for Integrative System of Autonomous Environmental Signal Recognition and Memorization for Plant Plasticity
Place of Presentation
ウェルシーズン浜名湖(静岡県浜松市)
Year and Date
2015-11-18
Related Report
Int'l Joint Research
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[Presentation] Rapid and simple 3D imaging of whole plant tissues2015
Author(s)
Junko Hasegawa, Yuki Sakamoto, Satoru Nakagami, Shinichiro Sawa, Sachihiro Matsunaga
Organizer
The 1st Meeting of Young Scientists for Integrative System of Autonomous Environmental Signal Recognition and Memorization for Plant Plasticity
Place of Presentation
ウェルシーズン浜名湖(静岡県浜松市)
Year and Date
2015-11-18
Related Report
Int'l Joint Research
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[Presentation] Cyanidioschyzon merolaeにおけるオーロラキナーゼを介したミトコンドリア分裂制御メカニズムの解析2015
Author(s)
岡村枝里佳, 松永朋子, 加藤翔一, 坂本卓也, 井元祐太, 大沼みお, 野村有子, 中神弘史, 黒岩晴子, 河野重行, 黒岩常祥, 松永幸大
Organizer
日本植物学会第79回大会
Place of Presentation
朱鷺メッセ:新潟コンベンションセンター(新潟県新潟市)
Year and Date
2015-09-08
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[Presentation] 外界環境変化による細胞内pH動態解析2015
Author(s)
栗田和貴, 坂本卓也, 金鍾明, 関原明, 松永幸大
Organizer
日本植物形態学会第27回総会・大会
Place of Presentation
朱鷺メッセ:新潟コンベンションセンター(新潟県新潟市)
Year and Date
2015-09-05
Related Report
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