| Budget Amount *help |
¥15,860,000 (Direct Cost: ¥12,200,000、Indirect Cost: ¥3,660,000)
Fiscal Year 2016: ¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2015: ¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2014: ¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
|
|---|
| Outline of Final Research Achievements |
The honeybee mushroom bodies comprise 4 subtypes of class I Kenyon cells (KCs): the large-, middle- and small-type KCs, of which middle-type KCs preferentially express mKast. In the present study, we analyzed the function and evolution of the KC subtypes.
1)mKast was suggested to be involved in various brain functions in adult honeybees. 2)We first succeeded to establish genome-editing technique in the honeybee. 3)The number of KC subtypes increased from 1 in the sawflies to 2 in the parasitic wasps and then 3 in the hornets and honeybees, suggesting its relationship with the evolution of behavioral traits in Hymenopteran insects.
Our findings are internationally of most importance, that contribute not only to the understanding of the function of middle-type KCs but also to the progress of neurobiology in general.
|
