• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Microbial production of the useful C4 key compound

Research Project

Project/Area Number 26292042
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypePartial Multi-year Fund
Section一般
Research Field Applied microbiology
Research InstitutionOsaka Prefecture University

Principal Investigator

KATAOKA Michihiko  大阪府立大学, 生命環境科学研究科(系), 教授 (90252494)

Project Period (FY) 2014-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥16,510,000 (Direct Cost: ¥12,700,000、Indirect Cost: ¥3,810,000)
Fiscal Year 2016: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2015: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2014: ¥6,500,000 (Direct Cost: ¥5,000,000、Indirect Cost: ¥1,500,000)
Keywords微生物酵素 / 微生物 / 応用微生物 / 酵素 / 発酵 / バイオテクノロジー
Outline of Final Research Achievements

Using recombinant Escherichia coli, the fermentative production of the useful C4 key compound was examined. For this purpose, a novel biosynthetic pathway of the useful C4 key compound was designed, and then the enzymes catalyzing each reaction step were introduced into same E. coli cells. Furthermore, the gene disruption of the host E. coli cells and the optimization of fermentation were also examined.

Report

(4 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Annual Research Report
  • 2014 Annual Research Report
  • Research Products

    (7 results)

All 2016 2015 2014

All Journal Article (1 results) (of which Peer Reviewed: 1 results,  Acknowledgement Compliant: 1 results) Presentation (6 results) (of which Int'l Joint Research: 3 results,  Invited: 1 results)

  • [Journal Article] Fermentative production of 1-propanol from D-glucose, L-rhamnose and glycerol using recombinant Escherichia coli2016

    • Author(s)
      Mitsuru Matsubara, Nobuyuki Urano, Shohei Yamada, Ai Narutaki, Misaki Fujii, Michihiko Kataoka
    • Journal Title

      Journal of Bioscience and Bioengineering

      Volume: 印刷中 Issue: 4 Pages: 421-426

    • DOI

      10.1016/j.jbiosc.2016.03.011

    • NAID

      40020966120

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Presentation] Fermentative production of 1-propanol by metabolically engineered Escherichia coli2016

    • Author(s)
      Michihiko Kataoka, Mitsuru Mtsubara
    • Organizer
      The 14th China-Japan-Korea Symposium on Enzyme Engineering
    • Place of Presentation
      Nanning, China
    • Year and Date
      2016-11-16
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 組換え大腸菌を用いたラムノースを出発基質とする1-プロパノール発酵生産2016

    • Author(s)
      松原充, 浦野信行, 鳴滝藍, 山田尚平, 片岡道彦
    • Organizer
      第68回日本生物工学会大会
    • Place of Presentation
      富山市
    • Year and Date
      2016-09-28
    • Related Report
      2016 Annual Research Report
  • [Presentation] 代謝改変した組換え大腸菌による1-プロパノール発酵生産2016

    • Author(s)
      山田尚平, 松原充, 浦野信行, 片岡道彦
    • Organizer
      日本農芸化学会関西支部第495回講演会
    • Place of Presentation
      大阪府堺市
    • Year and Date
      2016-07-09
    • Related Report
      2016 Annual Research Report
  • [Presentation] Fermentative production of 1-propanol from glycerol using metabolically engineered Escherichia coli2015

    • Author(s)
      Michihiko Kataoka, Mitsuru Matsubara, Nobuyuki Urano, Misaki Fujii
    • Organizer
      Enzyme Engineering XXIII
    • Place of Presentation
      St. Petersburg, Florida(米国)
    • Year and Date
      2015-09-06
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Fermentative production of 1-propanol using metabolically engineered Escherichia coli2015

    • Author(s)
      Nobuyuki Urano, Mistura Matsubara, Shohei Yamada, Michihiko Kataoka
    • Organizer
      KMB2015
    • Place of Presentation
      慶州(韓国)
    • Year and Date
      2015-06-24
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Metabolic engineering of Escherichia coli for fermentative production of 1-propanol from glycerol2014

    • Author(s)
      Mitsuru Matsubara, Nobuyuki Urano, Misaki Fujii, Michihiko Kataoka
    • Organizer
      Active Enzyme Molecule 2014
    • Place of Presentation
      富山国際会議場(富山市)
    • Year and Date
      2014-12-17 – 2014-12-19
    • Related Report
      2014 Annual Research Report

URL: 

Published: 2014-04-04   Modified: 2018-03-22  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi