Microbial production of the useful C4 key compound
| Project/Area Number |
26292042
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Partial Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Applied microbiology
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| Research Institution | Osaka Prefecture University |
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Principal Investigator |
KATAOKA Michihiko 大阪府立大学, 生命環境科学研究科(系), 教授 (90252494)
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥16,510,000 (Direct Cost: ¥12,700,000、Indirect Cost: ¥3,810,000)
Fiscal Year 2016: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2015: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2014: ¥6,500,000 (Direct Cost: ¥5,000,000、Indirect Cost: ¥1,500,000)
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| Keywords | 微生物酵素 / 微生物 / 応用微生物 / 酵素 / 発酵 / バイオテクノロジー |
|---|
| Outline of Final Research Achievements |
Using recombinant Escherichia coli, the fermentative production of the useful C4 key compound was examined. For this purpose, a novel biosynthetic pathway of the useful C4 key compound was designed, and then the enzymes catalyzing each reaction step were introduced into same E. coli cells. Furthermore, the gene disruption of the host E. coli cells and the optimization of fermentation were also examined.
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Report
(4 results)
Research Products
(7 results)
