| Project/Area Number |
26292059
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Partial Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Bioorganic chemistry
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| Research Institution | Shizuoka University |
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Principal Investigator |
Watanabe Naoharu 静岡大学, 創造科学技術大学院, 特任教授 (90230979)
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| Co-Investigator(Renkei-kenkyūsha) |
MASE Nobuyuki 静岡大学, 工学部, 教授 (40313936)
OHNISHI Toshiyuki 静岡大学, 農学部, 准教授 (60542165)
NARUMI Tetsuo 静岡大学, 工学部, 准教授 (50547867)
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥16,250,000 (Direct Cost: ¥12,500,000、Indirect Cost: ¥3,750,000)
Fiscal Year 2016: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Fiscal Year 2015: ¥5,980,000 (Direct Cost: ¥4,600,000、Indirect Cost: ¥1,380,000)
Fiscal Year 2014: ¥7,670,000 (Direct Cost: ¥5,900,000、Indirect Cost: ¥1,770,000)
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| Keywords | 花芽誘導 / オキシリピン / レムナ / 構造活性相関 / 構造要求性 / 代謝経路 / アオウキクサ / 全合成 / 花芽誘導物質 / 有機合成 / 代謝抵抗性 / 合成 / 遺伝子発現 |
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| Outline of Final Research Achievements |
We have isolated a flower-inducing compound, LDS1, from a free-floating aquatic plant, Lemna paucicostata. To afford the sufficient amounts of LDS1, we successfully synthesized LDS1. We also synthesized LDS1 analogs by modifying carbon-chain length, number of hydroxyl groups, kept-reduction, position of double bounds to investigate structure-activity relationships. By using the LDS1 chemically synthesized, we have analyzed metabolic pathways for LDS1 in Lemna plants. One of the metabolites was tentatively identified as a reduction product of LDS1 in its double bound. Substantial amounts of LDS1 was produced in Lemna plants grown in the high-density stress conditions.
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