| Budget Amount *help |
¥16,770,000 (Direct Cost: ¥12,900,000、Indirect Cost: ¥3,870,000)
Fiscal Year 2016: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2015: ¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2014: ¥8,840,000 (Direct Cost: ¥6,800,000、Indirect Cost: ¥2,040,000)
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| Outline of Final Research Achievements |
In order to contribute to anti-aging through autophagy regulation by nutrition, we searched nutrients, especially amino acids and antioxidants, and rice protein as a possible regulatory food factors of autophagy, and investigated their regulatory mechanisms, i.e., signaling mechanisms at the formation step of autophagosome, the transcription step, and the relationship with aging gene, SIRT1 including acetylation. These findings will give the evidence for food functions on elderly people.
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