| Budget Amount *help |
¥15,990,000 (Direct Cost: ¥12,300,000、Indirect Cost: ¥3,690,000)
Fiscal Year 2016: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2015: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2014: ¥7,020,000 (Direct Cost: ¥5,400,000、Indirect Cost: ¥1,620,000)
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| Outline of Final Research Achievements |
We established culture condition to differentiate stromal-vascular cells originated from bovine adipose tissues to brite (brown in white) adipocytes. Retinoic acid had an inhibitory effect on expression of Ucp1, a gene predominantly expressed in brite adipocytes. Feeding vitamin A-restricted diet did not affect expression level in adipose tissues of Japanese Black fattening cattle. However, Ucp1 expression was slightly higher in brite adipocytes differentiated from stromal vascular cells isolated from vitamin A-restricted cattle than in those from control cattle.
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