• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Effects of dietary forage and calf starter on ruminal farmentation, microbiota and epithelial adaptation in calves during weaning transition

Research Project

Project/Area Number 26292156
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypePartial Multi-year Fund
Section一般
Research Field Veterinary medical science
Research InstitutionIwate University

Principal Investigator

Sato Shigeru  岩手大学, 農学部, 教授 (50455755)

Co-Investigator(Kenkyū-buntansha) 櫛引 史郎  国立研究開発法人農業・食品産業技術総合研究機構, その他部局等, 研究員 (30355218)
Project Period (FY) 2014-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥16,120,000 (Direct Cost: ¥12,400,000、Indirect Cost: ¥3,720,000)
Fiscal Year 2016: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2015: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2014: ¥5,980,000 (Direct Cost: ¥4,600,000、Indirect Cost: ¥1,380,000)
Keywords潜在性ルーメンアシドーシス / 子牛 / ルーメン / 離乳 / エンドトキシン / 代謝・内分泌機能 / 免疫機能 / SARA / 第一胃 / SARA(潜在性ルーメンアシドーシス) / ルーメン(第一胃) / pH / 内分泌機能 / 免疫機構 / pH
Outline of Final Research Achievements

The objective of this study was to investigate the effects of dietary forage and calf starter on the risks for subacute ruminal acidosis (SARA), immune ability, and metabolic capacity in weaning calves. The ruminal pH was significantly higher in the HAY group, and total VFA concentration was not significant between the two groups. The 454 pyrosequencing analysis revealed that the bacterial diversity was significantly higher, and recovered more rapidly from damages during weaning transition in the HAY group compared with the CON group. Ruminal bacterial communities of the two groups distinctly separate from each other after weaning in the PCoA analysis. Meanwhile, 212 DEGs (P<0.05, fold change >2) could be mapped to a known molecular function in the top upstream regulator and top network analyses by the IPA software, and the proliferation of the rumen epithelium cells was suggested to be regulated by growth factors (TGFB1) and signaling pathways (EGF and IGFBP).

Report

(4 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Annual Research Report
  • 2014 Annual Research Report
  • Research Products

    (13 results)

All 2016 2015 2014

All Journal Article (3 results) (of which Int'l Joint Research: 2 results,  Peer Reviewed: 3 results,  Open Access: 3 results,  Acknowledgement Compliant: 2 results) Presentation (10 results) (of which Int'l Joint Research: 2 results,  Invited: 1 results)

  • [Journal Article] Effects of dietary forage and calf starter on ruminal pH and bacteria in Holstein calves during weaning transition.2016

    • Author(s)
      Yo-Han Kim, Nagata R., Ohtani N., Ichijo T., Ikuta K. and Sato S.
    • Journal Title

      Front Microbiol.

      Volume: 7 Pages: 1-12

    • DOI

      10.3389/fmicb.2016.01575

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Effects of dietary forage and calf starter on ruminal pH and transcriptomic adaptation of the rumen epithelium in Holstein calves during the weaning transition.2016

    • Author(s)
      Yo-Han Kim, Touji N., Kizaki K., Kushibiki S., Ichijo T. and Sato S.
    • Journal Title

      Physiol. Genomics

      Volume: 48 Issue: 11 Pages: 803-809

    • DOI

      10.1152/physiolgenomics.00086.2016

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Subacute ruminal acidosis (SARA) challenge, ruminal condition and cellular immunity in cattle2015

    • Author(s)
      Shigeru Sato
    • Journal Title

      Japanese Journal of Veterinary Research

      Volume: 63 Issue: 1 Pages: none

    • DOI

      10.14943/jjvr.63.suppl.s25

    • NAID

      120005540301

    • ISSN
      0047-1917
    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Presentation] 黒毛和種下痢子牛の前胃液および糞便における細菌叢構成2016

    • Author(s)
      中村聡一郎, 高嶋恵輔, 木村 淳, 生田健太郎, 長井和哉, 一條俊浩, 佐藤 繁
    • Organizer
      第159回日本獣医学会学術集会
    • Place of Presentation
      日本大学生物資源科学部(神奈川県藤沢市)
    • Year and Date
      2016-09-06
    • Related Report
      2016 Annual Research Report
  • [Presentation] 活性型酵母製剤投与牛における実験的亜急性第一胃アシドーシス (SARA) 誘発の影響2016

    • Author(s)
      渡部祐未, 櫛引史郎, 生田健太郎, 長井和哉, 一條俊浩, 佐藤 繁
    • Organizer
      第159回日本獣医学会学術集会
    • Place of Presentation
      日本大学生物資源科学部(神奈川県藤沢市)
    • Year and Date
      2016-09-06
    • Related Report
      2016 Annual Research Report
  • [Presentation] Effects of dietary forage and calf starter on ruminal pH and transcriptomic adaptation of rumen epithelium in Holstein calves during weaning transition.2016

    • Author(s)
      Kim Yohan, 渡部祐未, 田路矩之, 木崎景一郎, 一條俊浩, 佐藤 繁
    • Organizer
      第159回日本獣医学会学術集会
    • Place of Presentation
      日本大学生物資源科学部(神奈川県藤沢市)
    • Year and Date
      2016-09-06
    • Related Report
      2016 Annual Research Report
  • [Presentation] Changes in ruminal pH, VFA, and microbial composition of cattle with repeated SARA challenges2015

    • Author(s)
      Shigeru SATO, Rie NAGATA, Natsuki OHTANI, Kentaro IKUTA and Keiji OKADA
    • Organizer
      32th World Veterinary Congress
    • Place of Presentation
      Istanbul, Turkey
    • Year and Date
      2015-09-13
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 亜急性第一胃アシドーシス反復誘発牛における第一胃液pHと細菌叢の変化2015

    • Author(s)
      大谷夏輝,永田利恵,Kim Yohan,渡部祐未,生田健太郎,岡田啓司,佐藤 繁
    • Organizer
      第158回日本獣医学会学術集会
    • Place of Presentation
      北里大学(十和田市)
    • Year and Date
      2015-09-07
    • Related Report
      2015 Annual Research Report
  • [Presentation] Effects of dietary forage and calf starter on ruminal pH and bacterial community in Holstein calves during weaning transition2015

    • Author(s)
      Kim Yohan, Natsuki Ohtani, Yu-mi Watanabe, Keiji Okada, and Shigeru Sato
    • Organizer
      第158回日本獣医学会学術集会
    • Place of Presentation
      北里大学(十和田市)
    • Year and Date
      2015-09-07
    • Related Report
      2015 Annual Research Report
  • [Presentation] Changes in pH and microbial composition in the ruminal and reticular fluids of SARA cattle2015

    • Author(s)
      Shigeru SATO, Rie NAGATA, Akira OHKUBO and Keiji OKADA
    • Organizer
      66th annual meeting of the European Federation of Animal Science
    • Place of Presentation
      Warsaw, Polamd
    • Year and Date
      2015-08-31
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 亜急性第一胃アシドーシス牛における第一胃液性状と細胞性免疫機能2015

    • Author(s)
      佐藤 繁
    • Organizer
      栄養、代謝、免疫並びに遺伝学の応用による乳牛の疾病予防と生産性向上のためにグローバル・アプローチ
    • Place of Presentation
      岡山コンベンションセンター(岡山市)
    • Year and Date
      2015-02-13 – 2015-02-14
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] Effect of hay feeding on pH and volatile fatty acid (VFA) in the ruminal fluid of Holstein calves at weaning2014

    • Author(s)
      Shigeru SATO, Rie NAGATA, Kentaro IKUTA, Shiro KUSHIBIKI and Keiji OKADA
    • Organizer
      World Congress on Controversies, Debates and Consensus in Veterinary Medicine
    • Place of Presentation
      Prague (Czech Republic)
    • Year and Date
      2014-10-23 – 2014-10-25
    • Related Report
      2014 Annual Research Report
  • [Presentation] 離乳期子牛における給与飼料と第一胃液pHの関係2014

    • Author(s)
      佐藤 繁, 永田利恵, 桃田優子, 生田健太郎, 櫛引史郎, 岡田啓司
    • Organizer
      第157回日本獣医学会学術集会
    • Place of Presentation
      北海道大学(札幌市)
    • Year and Date
      2014-09-09 – 2014-09-11
    • Related Report
      2014 Annual Research Report

URL: 

Published: 2014-04-04   Modified: 2018-03-22  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi