Budget Amount *help |
¥16,120,000 (Direct Cost: ¥12,400,000、Indirect Cost: ¥3,720,000)
Fiscal Year 2016: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2015: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2014: ¥5,980,000 (Direct Cost: ¥4,600,000、Indirect Cost: ¥1,380,000)
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Outline of Final Research Achievements |
The objective of this study was to investigate the effects of dietary forage and calf starter on the risks for subacute ruminal acidosis (SARA), immune ability, and metabolic capacity in weaning calves. The ruminal pH was significantly higher in the HAY group, and total VFA concentration was not significant between the two groups. The 454 pyrosequencing analysis revealed that the bacterial diversity was significantly higher, and recovered more rapidly from damages during weaning transition in the HAY group compared with the CON group. Ruminal bacterial communities of the two groups distinctly separate from each other after weaning in the PCoA analysis. Meanwhile, 212 DEGs (P<0.05, fold change >2) could be mapped to a known molecular function in the top upstream regulator and top network analyses by the IPA software, and the proliferation of the rumen epithelium cells was suggested to be regulated by growth factors (TGFB1) and signaling pathways (EGF and IGFBP).
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