| Budget Amount *help |
¥16,120,000 (Direct Cost: ¥12,400,000、Indirect Cost: ¥3,720,000)
Fiscal Year 2017: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Fiscal Year 2016: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2015: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2014: ¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
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| Outline of Final Research Achievements |
he pituitary gland is a major endocrine organ for maintenance of vital functions. This project focuses on the characteristics of pituitary stem/progenitor cells and the roles on pituitary organogenesis and maintenance. Our studies have demonstrated following important results: 1) characteristic localizations of several specific factors, 2) isolation of one of two types of stem/progenitor cell niches, 3) demonstration of characteristic differentiation into hormone-producing and non-hormone-producing cells, 4) novel isolation of stem/progenitor cells by using anti-CD9 antibody and differentiation into vascular endothelial cell-like cells, 5) invasion of two types of the neural crest lineage cells into the anterior and posterior lobes of the pituitary gland, respectively.
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