| Budget Amount *help |
¥16,250,000 (Direct Cost: ¥12,500,000、Indirect Cost: ¥3,750,000)
Fiscal Year 2017: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2016: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Fiscal Year 2015: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Fiscal Year 2014: ¥8,970,000 (Direct Cost: ¥6,900,000、Indirect Cost: ¥2,070,000)
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| Outline of Final Research Achievements |
Follicular lymphoma is one of the most frequent lymmphoma, and it has increased in number of patients: approximately 6000 new patients a year and it is almost 20% of all lymphoma. Although this lymphoma is quite indolent clinical course, it recurres so freqently, and high-grade transformation is the serious problem to control. We revealed that cancer initiating cells are present in this lymphoma which is closely associated with high frequent recurrence, and examined the role of c-MYC and BCL2 translocation at the course of high-grade transformation.
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