| Budget Amount *help |
¥16,120,000 (Direct Cost: ¥12,400,000、Indirect Cost: ¥3,720,000)
Fiscal Year 2016: ¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2015: ¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2014: ¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
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| Outline of Final Research Achievements |
The intestinal immune system is involved in the maintenance of immunological homeostasis in the gut. It is known that Peyer’s patches play a central role in regulating intestinal immunity, which is at least partly regulated by intestinal bacteria. In this study, we aim to clarify the function of Alcaligenes, a symbiotic bacteria found in Peyer's patches, in the regulation of intestinal immunity and found that Alcaligenes itself and Alcaligenes LPS possess unique features to moderately regulate intestinal immunity without induction of excessive inflammation.
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