A genome cohort focusing on psycho-social factors
Project/Area Number |
26293143
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Research Category |
Grant-in-Aid for Scientific Research (B)
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Allocation Type | Partial Multi-year Fund |
Section | 一般 |
Research Field |
Epidemiology and preventive medicine
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Research Institution | Nagoya City University |
Principal Investigator |
Suzuki Sadao 名古屋市立大学, 大学院医学研究科, 教授 (20226509)
|
Co-Investigator(Kenkyū-buntansha) |
西山 毅 名古屋市立大学, 大学院医学研究科, 准教授 (40571518)
|
Project Period (FY) |
2014-04-01 – 2019-03-31
|
Project Status |
Completed (Fiscal Year 2018)
|
Budget Amount *help |
¥17,160,000 (Direct Cost: ¥13,200,000、Indirect Cost: ¥3,960,000)
Fiscal Year 2018: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2017: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2016: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2015: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2014: ¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
|
Keywords | 疫学 / コホート研究 / 分子疫学 / ゲノムコホート |
Outline of Final Research Achievements |
The association between psycho-social factors and public health is still unclear. In order to examine the association, we organized a new cohort with gene information. The investigation aimed to settle the cohort system. To make larger cohort group, we made a compact questionnaire with only validated and essential questions in 4 pages. We also developed work saving system using OCR and PDF documents. Furthermore, to ask corporation to established gene cohort groups by answering our questionnaire, we tried to gather as many persons as possible. As a result, database of about 16,000 participants (12,000 inside, and 4,000 from other cohort groups) was completed.
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Academic Significance and Societal Importance of the Research Achievements |
コホート研究は最もエビデンスが高い観察疫学研究であるが,研究期間がかかることと,大きい研究規模が必要なことから,実施が困難なデザインでもある.また,協力機関(主として検診機関)を探すのが困難なこと,ベースラインの情報量と研究参加者数とがトレードオフ関係にあること,リクルートにマンパワーが必要なこと,追跡のシステム整備が煩雑なこと,同意などの倫理的配慮が必要なことなど,新規のコホート研究を立ち上げるためにはクリアしなければならないハードルは多く,高い.今回,合計約15,000人のデータベースが完成したことは大きい成果であり,今後,このコホートを使用した独自研究が多数出てくることが期待される.
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Report
(6 results)
Research Products
(14 results)
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[Journal Article] Physical Activity Earlier in Life Is Inversely Associated With Insulin Resistance Among Adults in Japan2019
Author(s)
Fujita H, Hosono A, Shibata K, Tsujimura S, Oka K, Okamoto N, Kamiya M, Kondo F, Wakabayashi R, Ichikawa M, Yamada T, Suzuki S
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Journal Title
Journal of Epidemiology
Volume: 29
Issue: 2
Pages: 57-60
DOI
NAID
ISSN
0917-5040, 1349-9092
Year and Date
2019-02-05
Related Report
Peer Reviewed / Open Access
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[Journal Article] Handling missiong data in an FFQ: multiple imputation and nutrient intake estimates2019
Author(s)
Ichikawa M, Hosono A, Tamai Y, Watanabe M, Shibata K, Tsujimura S, Oka K, Fujita H, Okamoto N, Kamiya M, Kondo F, Wakabayashi R, Noguchi T, Isomura T, Imaeda N, Goto C, Tamaki Y, Suzuki S
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Journal Title
Public Health Nutrition
Volume: 26
Issue: 8
Pages: 1-10
DOI
Related Report
Peer Reviewed
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[Journal Article] A genome-wide association study in the Japanese population identifies the 12q24 locus for habitual coffee consumption: The J-MICC Study.2018
Author(s)
Hiroko Nakagawa-Senda, Tsuyoshi Hachiya, Atsushi Shimizu, Satoyo Hosono, Isao Oze, Miki, Watanabe, Keitaro Matsuo, Hidemi Ito, Megumi Hara, Yuichiro Nishida, Kaori Endoh, Kiyonori Kuriki, Sakurako Katsuura-Kamano, Kokichi Arisawa, Yora Nindita, Rie Ibusuki, Sadao Suzuki, Akihiro Hosono, et al.
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Journal Title
Scientific Report
Volume: 8
Issue: 1
Pages: 1493-1493
DOI
Related Report
Peer Reviewed / Open Access
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