| Budget Amount *help |
¥16,380,000 (Direct Cost: ¥12,600,000、Indirect Cost: ¥3,780,000)
Fiscal Year 2018: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2017: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2016: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2015: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2014: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
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| Outline of Final Research Achievements |
The aim of this study was the development of novel methods for estimation of age and for screening of trait-related CNVs. Consequently, the following results were obtained: (1) Methods for the determination of age-related biomolecules such as M-LPH at the RNA levels were developed. (2) Proteins that interact with M-LPH (H2AX etc.) were identified and it was suggested that M-LPH is involved in the maintenance of mtDNA and protects cells from mitochondrial dysfunction. (3) A simple method for screening of trait-related CNVs, which is useful for forensic casework, was developed.
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