| Budget Amount *help |
¥16,510,000 (Direct Cost: ¥12,700,000、Indirect Cost: ¥3,810,000)
Fiscal Year 2016: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2015: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2014: ¥8,710,000 (Direct Cost: ¥6,700,000、Indirect Cost: ¥2,010,000)
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| Outline of Final Research Achievements |
Fetal growth retardation is the cause of small-for-gestational age (SGA) and is a high-risk group of neurological post-injury. Various therapeutic interventions have been done to prevent post-neurological impairment, but none of them have been effective. In this study, SGA rats were inferior in early behavioral evaluation of neonates, and immune-histological analysis showed that nerve cells decreased. Intravenous administration of umbilical cord blood after birth improved behavior early in the neonatal period and also significantly increased neuronal cells immunologically. This suggested the possibility of novel therapy for neurological development of children with SGA.
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