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Quality assurance of 3 dimensional distribution of 4 beam components of neutron capture therapy - measurement with gel detector -

Research Project

Project/Area Number 26293281
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypePartial Multi-year Fund
Section一般
Research Field Radiation science
Research InstitutionHiroshima University

Principal Investigator

Kenichi Tanaka  広島大学, 工学研究科, 准教授 (70363075)

Co-Investigator(Kenkyū-buntansha) 櫻井 良憲  京都大学, 原子炉実験所, 准教授 (20273534)
遠藤 暁  広島大学, 工学研究科, 教授 (90243609)
梶本 剛  広島大学, 工学研究科, 助教 (70633759)
田中 浩基  京都大学, 原子炉実験所, 助手 (70391274)
高田 純  札幌医科大学, 医療人育成センター, 教授 (00274134)
Project Period (FY) 2014-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥13,260,000 (Direct Cost: ¥10,200,000、Indirect Cost: ¥3,060,000)
Fiscal Year 2016: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2015: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2014: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Keywords医学物理学 / 放射線科学 / 放射線技術学 / 中性子捕捉療法 / 品質保証 / ゲル検出器 / 放射線治療物理学 / ビーム成分 / ゲル / 線量評価 / 弁別
Outline of Final Research Achievements

In neutron capture therapy (NCT), an essential factor is how to control the dimensions of the irradiation field. From the viewpoint of quality assurance and quality control (QA/QC), it is important to measure the three dimensional distribution of the thermal and epithermal neutrons, which are useful in NCT, and fast neutrons and gamma rays, which are not desirable for NCT. This project proposes the utilization of the gel detector as a three-dimensional radiation detector, combined with the enhancers to detect the aimed beam component for this purpose. Consequently, the required condition of the methodology was revealed. The research is still ongoing to realize the method in clinical trials, by evaluating the accuracy and improving the procedure.

Report

(5 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Annual Research Report
  • 2015 Annual Research Report
  • 2014 Annual Research Report
  • Research Products

    (30 results)

All 2018 2017 2016 2015 2014

All Journal Article (15 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 6 results,  Open Access: 1 results,  Acknowledgement Compliant: 8 results) Presentation (15 results) (of which Int'l Joint Research: 4 results,  Invited: 2 results)

  • [Journal Article] “Computational investigation of suitable polymer gel composition for the QA of the beam components of a BNCT irradiation field”2017

    • Author(s)
      K. Tanaka, Y. Sakurai, S. Hayashi T. Kajimoto, R. Uchida, H. Tanaka, T. Takata, G. Bengua, S. Endo,
    • Journal Title

      Applied Radiation and Isotopes

      Volume: 127 Pages: 253-259

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Investigation of 6Li compound suitable for beam component measurement using polymer gel detector for BNCT2017

    • Author(s)
      K. Tanaka, Y. Murakami, R. Maruta, S. Hayashi, T. Kajimoto, Y. Sakurai, H. Tanaka, S. Endo,
    • Journal Title

      Japanese Journal of Medical Physics

      Volume: 37 Pages: 43-43

    • Related Report
      2017 Annual Research Report
  • [Journal Article] Survey on nuclide enhancing sensitivity of gel detector to epithermal neutron for neutron capture therapy2017

    • Author(s)
      Y. Murakami, K. Tanaka, T. Kajimoto, Y. Sakurai, S. Hayashi, H. Tanaka, S. Endo
    • Journal Title

      Japanese Journal of Medical Physics

      Volume: 37 Pages: 155-155

    • Related Report
      2017 Annual Research Report
  • [Journal Article] Calculational survey of converter configuration for quality assurance of beam component distribution at KUR using imaging plate2017

    • Author(s)
      K. Tanaka, Y. Sakurai, T. Kajimoto, H. Tanaka, T. Takata, M. Suzuki, S. Endo
    • Journal Title

      KURRI Progress Report, 2016

      Volume: 1 Pages: 37-37

    • Related Report
      2017 Annual Research Report
  • [Journal Article] Quality assurance of spatial beam component distribution in neutron capture therapy using imaging plate2017

    • Author(s)
      K. Tanaka, Y. Sakurai, T. Kajimoto, H. Tanaka, T. Takata, I. Murata, S. Tamaki , S. Endo
    • Journal Title

      Radiation

      Volume: 43 Pages: 3-7

    • NAID

      40021210712

    • Related Report
      2016 Annual Research Report
    • Acknowledgement Compliant
  • [Journal Article] Design study of multi-imaging plate system for BNCT irradiation field at Kyoto university reactor2016

    • Author(s)
      Kenichi Tanaka, Yoshinori Sakurai, Tsuyoshi Kajimoto, Hiroki Tanaka, Takushi Takata, Satoru Endo
    • Journal Title

      Applied Radiation and Isotopes

      Volume: 115 Pages: 212-220

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] ポリマーゲル検出器を用いた中性子捕捉療法ビーム成分測定法の検討22016

    • Author(s)
      田中憲一、櫻井良憲、林慎一郎、梶本剛、田中浩基、高田卓志、高田純、遠藤暁
    • Journal Title

      Jpn. J. Med. Phys.

      Volume: 36(1) Pages: 94-94

    • Related Report
      2016 Annual Research Report 2015 Annual Research Report
    • Acknowledgement Compliant
  • [Journal Article] ポリマーゲル検出器を用いた中性子捕捉療法ビーム成分測定法の検討2015

    • Author(s)
      田中憲一、櫻井良憲、林慎一郎、梶本剛、田中浩基、高田卓志、高田純、遠藤暁
    • Journal Title

      Jpn. J. Med. Phys.

      Volume: 35(3) Pages: 68-68

    • Related Report
      2015 Annual Research Report
    • Acknowledgement Compliant
  • [Journal Article] “Measurement of spatial distribution of neutrons and gamma rays for BNCT using multi imaging plate system.”,2015

    • Author(s)
      K. Tanaka, Y. Sakurai, H. Tanaka, T. Kajimoto, T. Takata, J. Takada, S. Endo
    • Journal Title

      Applied Radiation and Isotopes

      Volume: 106 Pages: 125-128

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] A comparison of the dose distributions between the brachytherapy 125I source models, STM1251 and Oncoseed 6711, in a geometry lacking radiation equilibrium scatter conditions.2015

    • Author(s)
      K. Tanaka, K. Kamo, K. Tateoka, O. Asanuma, K. Sato, H. Takeda, K. Sakata, J. Takada
    • Journal Title

      Journal of Radiation Research

      Volume: 56 Issue: 2 Pages: 366-371

    • DOI

      10.1093/jrr/rru088

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Measurement of spatial distribution of neutrons and gamma rays for BNCT using multi imaging plate system2015

    • Author(s)
      Kenichi Tanaka, Yoshinori Sakurai, Hiroki Tanaka, Tsuyoshi Kajimoto, Takushi Takata, Jun Takada, Satoru Endo
    • Journal Title

      Applied Radiation and Isotopes

      Volume: 89

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Quality assurance of irradiation field for BNCT using twin imaging plate system2015

    • Author(s)
      1.K. Tanaka, Y. Sakurai, T. Kajimoto, H. Tanaka, T. Takata, J. Takada, M. Suzuki, S. Endo
    • Journal Title

      KURRI Progress Report

      Volume: 2015

    • Related Report
      2014 Annual Research Report
  • [Journal Article] Study on detecting spatial distribution of neutrons and gamma rays using multi imaging plate system2014

    • Author(s)
      K. Tanaka, S. Sakurai, S. Endo, J. Takada
    • Journal Title

      Applied Radiation and Isotopes

      Volume: 88 Pages: 143-146

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Experimental trial of measuring spatial distribution of neutrons and gamma rays in BNCT using multi imaging plate system2014

    • Author(s)
      K. Tanaka, Y. Sakurai, S. Endo, H. Tanaka, J. Takada
    • Journal Title

      Proceedings of 16th International Congress of Neutron Capture Therapy

      Volume: 1 Pages: 109-110

    • Related Report
      2014 Annual Research Report
    • Acknowledgement Compliant
  • [Journal Article] イメージングプレートを用いたビーム成分ごとの二次元強度分布測定法の検討2014

    • Author(s)
      田中憲一、櫻井良憲、遠藤暁、田中浩基、高田純
    • Journal Title

      第11回日本中性子捕捉療法学会学術大会抄録集

      Volume: 1 Pages: 88-88

    • Related Report
      2014 Annual Research Report
  • [Presentation] BNCTに関する測定技術2018

    • Author(s)
      田中憲一
    • Organizer
      日本応用物理学会放射線分科会医療放射線技術研究会「放射線検出器の研究シーズと医療現場ニーズに関するシンポジウム」~ホウ素中性子捕捉療法に関する測定技術と検出器開発~
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] Investigation of 6Li compound suitable for beam component measurement using polymer gel detector for BNCT2017

    • Author(s)
      Y. Murakami, K. Tanaka, T. Kajimoto, Y. Sakurai, S. Hayashi, H. Tanaka, S. Endo
    • Organizer
      8th Japan-Korea Joint meeting on Medical Physics
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Survey on nuclide enhancing sensitivity of gel detector to epithermal neutron for neutron capture therapy2017

    • Author(s)
      Y. Murakami, K. Tanaka, T. Kajimoto, Y. Sakurai, S. Hayashi, H. Tanaka, S. Endo
    • Organizer
      8th Japan-Korea Joint meeting on Medical Physics
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Study on irradiation field monitor for BNCT using multi imaging plate system2016

    • Author(s)
      K. Tanaka, Y. Sakurai, T. Kajimoto, T. Takata, H, Tanaka, S. Endo
    • Organizer
      17th International Congress of Neutron Capture Therapy
    • Place of Presentation
      Missouri, USA
    • Year and Date
      2016-10-08
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Investigation of beam component monitor for BNCT using gel detector2016

    • Author(s)
      K. Tanaka, Y. Sakurai, T. Kajimoto, S. Hayashi, H, Tanaka, T. Takata, J. Takada, S. Endo
    • Organizer
      17th International Congress of Neutron Capture Therapy
    • Place of Presentation
      Missouri, USA
    • Year and Date
      2016-10-08
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] ポリマーゲル検出器を用いた中性子捕捉療法ビーム成分測定法の検討22016

    • Author(s)
      田中憲一、櫻井良憲、林慎一郎、梶本剛、田中浩基、高田卓志、高田純、遠藤暁
    • Organizer
      第111回日本日本医学物理学会学術大会
    • Place of Presentation
      横浜
    • Year and Date
      2016-04-14
    • Related Report
      2016 Annual Research Report
  • [Presentation] ポリマーゲル検出器を用いた中性子捕捉療法ビーム成分測定法の検討22016

    • Author(s)
      田中憲一、櫻井良憲、林慎一郎、梶本剛、田中浩基、高田卓志、高田純、遠藤暁
    • Organizer
      第111回日本医学物理学会学術大会
    • Place of Presentation
      横浜
    • Year and Date
      2016-04-14
    • Related Report
      2015 Annual Research Report
  • [Presentation] 「中性子捕捉療法ビーム成分測定のためのポリマーゲル検出器の検討要旨集、(2016)35-37.2016

    • Author(s)
      村上裕堂、梶本 剛, 田中 憲一, 遠藤 暁
    • Organizer
      日本原子力学会中国・四国支部H28年度研究発表会
    • Place of Presentation
      坂出
    • Related Report
      2016 Annual Research Report
  • [Presentation] イメージングプレートを用いたBNCTビーム成分測定の進展2016

    • Author(s)
      田中憲一
    • Organizer
      第78回日本応用物理学会学術講演会
    • Place of Presentation
      新潟
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] 中性子捕捉療法ビーム成分測定のためのポリマーゲル検出器の検討2015

    • Author(s)
      田中憲一、櫻井良憲、林慎一郎、梶本剛、田中浩基、高田卓志、高田純、遠藤暁
    • Organizer
      第4回3次元ゲル線量計研究会
    • Place of Presentation
      東京
    • Year and Date
      2015-11-22
    • Related Report
      2015 Annual Research Report
  • [Presentation] ポリマーゲル検出器を用いた中性子捕捉療法ビーム成分測定法の検討2015

    • Author(s)
      田中憲一、櫻井良憲、林慎一郎、梶本剛、田中浩基、高田卓志、高田純、遠藤暁
    • Organizer
      第110回日本医学物理学会学術大会
    • Place of Presentation
      札幌
    • Year and Date
      2015-09-17
    • Related Report
      2015 Annual Research Report
  • [Presentation] 中性子捕捉療法ビーム成分分布測定のためのポリマーゲル検出器の設計検討2015

    • Author(s)
      田中憲一、櫻井良憲、林慎一郎、梶本剛、田中浩基、高田卓志、高田純、遠藤暁
    • Organizer
      第12回日本中性子捕捉療法学会学術大会
    • Place of Presentation
      神戸
    • Year and Date
      2015-09-04
    • Related Report
      2015 Annual Research Report
  • [Presentation] Investigation of irradiation field monitor for BNCT using multi imaging plate system.2015

    • Author(s)
      K. Tanaka, Y. Sakurai, H. Tanaka, T. Kajimoto, T. Takata, J. Takada, S. Endo
    • Organizer
      International Congress of Radiation Research 2015
    • Place of Presentation
      Kyoto, Japan.
    • Year and Date
      2015-05-22 – 2015-05-26
    • Related Report
      2014 Annual Research Report
  • [Presentation] イメージングプレートを用いたビーム成分ごとの二次元強度分布測定法の検討2014

    • Author(s)
      田中憲一、櫻井良憲、遠藤暁、田中浩基、高田純
    • Organizer
      第11回日本中性子捕捉療法学会学術大会
    • Place of Presentation
      大阪
    • Year and Date
      2014-07-07 – 2014-07-09
    • Related Report
      2014 Annual Research Report
  • [Presentation] “Experimental trial of measuring spatial distribution of neutrons and gamma rays in BNCT using multi imaging plate system”2014

    • Author(s)
      K. Tanaka, Y. Sakurai, S. Endo, H. Tanaka, J. Takada
    • Organizer
      16th International Congress of Neutron Capture Therapy
    • Place of Presentation
      Helsinki, Finland.
    • Year and Date
      2014-06-22 – 2014-06-26
    • Related Report
      2014 Annual Research Report

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Published: 2014-04-04   Modified: 2019-03-29  

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