Research for risk factors and potential therapeutic targets of musculoskeletal disorders caused by spinal disease and comorbidities

• Project/Area Number: 26293329
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Partial Multi-year Fund
• Section: 一般
• Research Field: Orthopaedic surgery
• Research Institution: National Rehabilitation Center for Persons with Disabilities
• Principal Investigator: AKUNE Toru 国立障害者リハビリテーションセンター(研究所), 病院(併任研究所), 副院長 (60282662)
• Co-Investigator(Kenkyū-buntansha): 村木 重之 東京大学, 医学部附属病院, 登録研究員 (40401070) ; 吉村 典子 東京大学, 医学部附属病院, 特任教授 (60240355) ; 岡 敬之 東京大学, 医学部附属病院, 特任准教授 (60401064)
• Project Period (FY): 2014-04-01 – 2018-03-31
• Project Status: Completed (Fiscal Year 2017)
• Budget Amount: ¥15,730,000 (Direct Cost: ¥12,100,000、Indirect Cost: ¥3,630,000); Fiscal Year 2017: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000); Fiscal Year 2016: ¥6,110,000 (Direct Cost: ¥4,700,000、Indirect Cost: ¥1,410,000); Fiscal Year 2015: ¥6,630,000 (Direct Cost: ¥5,100,000、Indirect Cost: ¥1,530,000); Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
• Keywords: 医療・福祉

Outline of Final Research Achievements

This study investigated epidemiologic evidence of spinal diseases and comorbidities using database of the ROAD (Research on Osteoarthritis/ osteoporosis Against Disability) and the Wakayama Spine Study. Data collection of musculoskeletal diseases and disorders including spinal diseases in population-based cohort of Japanese men and women was performed in the ROAD cohort and the Wakayama Spine Study cohort, which was a sub-cohort of the ROAD. Prevalence of cervical myelopathy, diffuse idiopathic skeletal hyperostosis, lumbar disc degeneration, tandem spinal stenosis, and acetabular dysplasia was examined, and association of pain and indices of spinal diseases and comorbidities was investigated and reported. Further, incidence and risk factors of lumbar spondylosis, lumbar disc degeneration, sarcopenia, and certified need of care in the long-term care insurance system was investigated and reported.

Research Products

• [Journal Article] Association of Lumbar Spondylolisthesis with Low Back Pain and Symptomatic Lumbar Spinal Stenosis in a Population-based Cohort: The Wakayama Spine Study. (2017)
  • Author(s): Ishimoto Y, Yoshimura N, Muraki S, Yamada H, Nagata K, Hashizume H, Takiguchi N, Minamide A, Oka H, Tanaka S, Kawaguchi H, Nakamura K, Akune T, Yoshida M.
  • Journal Title: Spine Volume: 印刷中 Issue: 11 Pages: E666-E671
  • DOI: 10.1097/brs.0000000000001960
  • Peer Reviewed
• [Journal Article] Progression, incidence, and risk factors for intervertebral disc degeneration in a longitudinal population-based cohort: the Wakayama Spine Study. (2017)
  • Author(s): Teraguchi M, Yoshimura N, Hashizume H, Yamada H, Oka H, Minamide A, Nagata K, Ishimoto Y, Kagotani R, Kawaguchi H, Tanaka S, Akune T, Nakamura K, Muraki S, Yoshida M.
  • Journal Title: Osteoarthritis Cartilage Volume: 印刷中 Issue: 7 Pages: 1122-1131
  • DOI: 10.1016/j.joca.2017.01.001
  • NAID: 40021443587
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Serum Levels of Matrix Metalloproteinase-3 and Autoantibodies Related to 2 Rheumatoid Arthritis in the General Japanese Population and their Association with Osteoporosis and Osteoarthritis: The ROAD Study (2017)
  • Author(s): Kodama R, Muraki S, Iidaka T, Oka H, Teraguhi M, Kagotani R, Asai Y, Hashizume H, Yoshida M, Kawaguchi H, Nakamura K, Akune T, Tanaka S, Yoshimura N.
  • Journal Title: J Bone Miner Metab Volume: in press Issue: 2 Pages: 246-253
  • DOI: 10.1007/s00774-017-0834-7
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] The prevalence of tandem spinal stenosis and its characteristics in a population-based MRI study: The Wakayama Spine Study (2017)
  • Author(s): Nagata K, Yoshimura N, Hashizume H, Ishimoto Y, Muraki S, Yamada H, Oka H, Kawaguchi H, Akune T, Tanaka S, Nakamura K, Yoshida M
  • Journal Title: Eur Spine J Volume: in press Issue: 10 Pages: 2529-2535
  • DOI: 10.1007/s00586-017-5072-0
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Sagittal spino-pelvic alignment in adults (2017)
  • Author(s): Asai Y, Tsutsui S, Oka H, Yoshimura N, Hashizume H, Yamada H, Akune T, Muraki S, Matsudaira K, Kawaguchi H, Nakamura K, Tanaka S, Yoshida M.
  • Journal Title: PLoS One Volume: Jun 6;12(6) Issue: 6 Pages: e0178697-e0178697
  • DOI: 10.1371/journal.pone.0178697
  • Peer Reviewed / Open Access
• [Journal Article] Radiographic measurements of the hip joint and their associations with hip pain in Japanese men and women: the Research on Osteoarthritis/osteoporosis Against Disability (ROAD) study. (2017)
  • Author(s): Iidaka T, Muraki S, Oka H, Kodama R, Tanaka S, Kawacughi H, Nakamura K, Akune T, Yoshimura N
  • Journal Title: Osteoarthritis Cartilage Volume: 25 Issue: 12 Pages: 2072-2079
  • DOI: 10.1016/j.joca.2017.08.008
  • Peer Reviewed / Open Access
• [Journal Article] MRI-defined paraspinal muscle morphology in Japanese population: The Wakayama Spine Study. (2017)
  • Author(s): Sasaki T, Yoshimura N, Hashizume H, Yamada H, Oka H, Matsudaira K, Iwahashi H, Shinto K, Ishimoto Y, Nagata K, Teraguchi M, Kagotani R, Muraki S, Akune T, Tanaka S, Kawaguchi H, Nakamura K, Minamide A, Nakagawa Y, Yoshida M.
  • Journal Title: PLoS One Volume: 12 Issue: 11 Pages: e0187765-e0187765
  • DOI: 10.1371/journal.pone.0187765
  • Peer Reviewed / Open Access
• [Journal Article] Is osteoporosis a predictor for future sarcopenia, or vice-versa? Four-year observations between the second and third ROAD study surveys. (2017)
  • Author(s): Yoshimura N, Muraki S, Oka H, Iidaka T, Kodama R, Kawaguchi H, Nakamura K, Tanaka S, Akune T:
  • Journal Title: Osteoporos Int Volume: 28 Issue: 1 Pages: 1-7
  • DOI: 10.1007/s00198-016-3823-0
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Prevalence of hand osteoarthritis and its relationship to hand pain and grip strength in Japan: The third survey of the ROAD study. (2016)
  • Author(s): Kodama R, Muraki S, Oka H, Iidaka T, Teraguchi M, Kagotani R, Asai Y, Yoshida M, Morizaki Y, Tanaka S, Kawaguchi H, Nakamura K, Akune T, Yoshimura N.
  • Journal Title: Mod Rheumatol Volume: 26 Issue: 5 Pages: 767-773
  • DOI: 10.3109/14397595.2015.1130673
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] The Association between the Cross-Sectional Area of the Dural Sac and Low Back Pain in a Large Population: The Wakayama Spine Study. (2016)
  • Author(s): Iwahashi H, Yoshimura N, Hashizume H, Yamada H, Oka H, Matsudaira K, Shinto K, Ishimoto Y, Nagata K, Teraguchi M, Kagotani R, Muraki S, Akune T, Tanaka S, Kawaguchi H, Nakamura K, Minamide A, Nakagawa Y, Yoshida M.
  • Journal Title: PLoS One Volume: 11 Issue: 8 Pages: e0160002-e0160002
  • DOI: 10.1371/journal.pone.0160002
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Classification of High Intensity Zones of the Lumbar Spine and Their Association with Other Spinal MRI Phenotypes: The Wakayama Spine Study. (2016)
  • Author(s): Teraguchi M, Samartzis D, Hashizume H, Yamada H, Muraki S, Oka H, Cheung JP, Kagotani R, Iwahashi H, Tanaka S, Kawaguchi H, Nakamura K, Akune T, Cheung KM, Yoshimura N, Yoshida M.
  • Journal Title: PLoS One Volume: 11 Issue: 9 Pages: e0160111-e0160111
  • DOI: 10.1371/journal.pone.0160111
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Metabolic Syndrome Components Are Associated with Intervertebral Disc Degeneration: The Wakayama Spine Study. (2016)
  • Author(s): Teraguchi M, Yoshimura N, Hashizume H, Muraki S, Yamada H, Oka H, Minamide A, Ishimoto Y, Nagata K, Kagotani R, Tanaka S, Kawaguchi H, Nakamura K, Akune T, Yoshida M.
  • Journal Title: PLoS One Volume: 11 Issue: 2 Pages: e0147565-e0147565
  • DOI: 10.1371/journal.pone.0147565
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Prevalence of radiographic hip osteoarthritis and its association with hip pain in Japanese men and women: The ROAD study. (2016)
  • Author(s): Iidaka T, Muraki S, Akune T, Oka H, Kodama R, Tanaka S, Kawaguchi H, Nakamura K, Yoshimura N
  • Journal Title: Osteoarthritis Cartilage Volume: 24 Issue: 1 Pages: 117-123
  • DOI: 10.1016/j.joca.2015.07.017
  • Peer Reviewed
• [Journal Article] The association of combination of disc degeneration, endplate signal change, and Schmorl node with low back pain in a large population study: the Wakayama Spine Study (2015)
  • Author(s): Teraguchi M, Yoshimura N, Hashizume H, Muraki S, Yamada H, Oka H, Minamide A, Nakagawa H, Ishimoto Y, Nagata K, Kagotani R, Tanaka S, Kawaguchi H, Nakamura K, Akune T, Yoshida M.
  • Journal Title: Spine J Volume: 15 Issue: 4 Pages: 622-628
  • DOI: 10.1016/j.spinee.2014.11.012
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Quadriceps muscle strength, radiographic knee osteoarthritis and knee pain: The ROAD study. (2015)
  • Author(s): Muraki S, Akune T, Teraguchi M, Kagotani R, Asai Y, Yoshida M, Tokimura F, Tanaka S, Oka H, Kawaguchi H, Nakamura K, Yoshimura N
  • Journal Title: BMC musculoskeltal disorders Volume: 16 Issue: 1 Pages: 305-305
  • DOI: 10.1186/s12891-015-0737-5
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Joint space narrowing, body mass index and knee pain: The ROAD study. (2015)
  • Author(s): Muraki S, Akune T, En-yo Y, Yoshida M, Suzuki T, Yoshida H, Ishibashi H, Tokimura F, Yamamoto S, Tanaka S, Nakamura K, Kawaguchi H, Oka H, Yoshimura N
  • Journal Title: Osteoarthritis Cartilage Volume: 23 Issue: 6 Pages: 874-881
  • DOI: 10.1016/j.joca.2015.01.011
  • Peer Reviewed
• [Journal Article] Does osteophytosis at the knee predict health-related quality of life decline? A 3-year follow-up of the ROAD study. (2015)
  • Author(s): Muraki S, Akune T, Nagata K, Ishimoto Y, Yoshida M, Tokimura F, Tanaka S, Kawaguchi H, Nakamura K, Oka H, Yoshimura N.
  • Journal Title: Clin Rheumatol. Volume: 34 Issue: 9 Pages: 1589-1597
  • DOI: 10.1007/s10067-014-2687-y
  • Peer Reviewed
• [Journal Article] Association between new indices in the locomotive syndrome risk test and decline in mobility: third survey of the ROAD study. (2015)
  • Author(s): Yoshimura N, Musaki S, Oka H, Tanaka S, Ogata T, Kawaguchi H, Akune T, Nakamura K
  • Journal Title: J Orthop Sci Volume: 20 Issue: 5 Pages: 896-905
  • DOI: 10.1007/s00776-015-0741-5
  • Peer Reviewed / Open Access
• [Journal Article] Factors affecting changes in the serum levels of 25-hydroxyvitamin D: A 3-year follow-up of the ROAD study. (2015)
  • Author(s): Yoshimura N, Muraki S, Oka H, Nakamura K, Kawaguchi H, Tanaka S, Akune T
  • Journal Title: Osteoporos Int Volume: 26 Issue: 11 Pages: 2597-605
  • DOI: 10.1007/s00198-015-3184-0
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Urinary 8-iso-prostaglandin F2a as a marker of metabolic risks in the general Japanese population: The ROAD study. (2015)
  • Author(s): Mure K, Yoshimura N, Hashimoto M, Muraki S, Oka H, Tanaka S, Kawaguchi H, Nakamura K, Akune T, Takeshita T
  • Journal Title: Obesity 23:1517-1524, 2015. Volume: 23 Issue: 7 Pages: 1517-1524
  • DOI: 10.1002/oby.21130
  • Peer Reviewed
• [Journal Article] Mutual associations among musculoskeletal diseases and metabolic syndrome components: A 3-year follow-up of the ROAD study. (2015)
  • Author(s): Yoshimura N, Muraki S, Oka H, Tanaka S, Kawaguchi H, Nakamura K, Akune T.
  • Journal Title: Mod Rheumatol. Volume: 25 Issue: 3 Pages: 438-448
  • DOI: 10.3109/14397595.2014.972607
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Serum levels of 25-hydroxyvitamin D and occurrence of musculoskeletal diseases, such as osteoporosis, knee osteoarthritis and lumbar spondylosis: A three-year follow-up of the road study. (2015)
  • Author(s): Yoshimura N, Muraki S, Oka H, Nakamura K, Kawaguchi H, Tanaka S, Akune T
  • Journal Title: Osteoporos Int Volume: 26 Issue: 1 Pages: 151-161
  • DOI: 10.1007/s00198-014-2844-9
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Incidence of disability and its associated factors in Japanese men and women: the Longitudinal Cohorts of Motor System Organ (LOCOMO) study. (2015)
  • Author(s): Yoshimura N, Akune T, Fujiwara S, Shimizu Y, Yoshida H, Nishiwaki Y, Sudo A, Omori G, Yoshida M, Shimokata H, Suzuki T, Muraki S, Oka H, Nakamura K.
  • Journal Title: J Bone Miner Metab Volume: 33 Issue: 2 Pages: 186-191
  • DOI: 10.1007/s00774-014-0573-y
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Prevalence of diffuse idiopathic skeletal hyperostosis (DISH) of the whole spine and its association with lumbar spondylosis and knee osteoarthritis: the ROAD study. (2015)
  • Author(s): Kagotani R, Yoshida M, Muraki S, Oka H, Hashizume H, Yamada H, Enyo Y, Nagata K, Ishimoto Y, Teraguchi M, Tanaka S, Nakamura K, Kawaguchi H, Akune T, Yoshimura N.
  • Journal Title: J Bone Miner Metab Volume: 33 Issue: 2 Pages: 221-229
  • DOI: 10.1007/s00774-014-0583-9
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] The prevalence of cervical myelopathy among subjects with narrow cervical spinal canal in a population-based MRI study: The Wakayama Spine Study. (2014)
  • Author(s): 52. Nagata K, Yoshimura N, Hashizume H, Muraki S, Ishimoto Y, Yamada H, Takiguchi N, Nakagawa Y, Minamide A, Oka H, Kawaguchi H, Nakamura K, Akune T, Yoshida M
  • Journal Title: Spine J Volume: in press Issue: 12 Pages: 2811-2817
  • DOI: 10.1016/j.spinee.2014.03.051
  • Peer Reviewed / Open Access
• [Journal Article] Association of knee osteoarthritis with onset and resolution of pain and physical functional disability: the ROAD study. (2014)
  • Author(s): Muraki S, Akune T, Nagata K, Ishimoto Y, Yoshida M, Tokimura F, Tanaka S, Oka H, Kawaguchi H, Nakamura K, Yoshimura N
  • Journal Title: Mod Rheumatol. Volume: 24 Issue: 6 Pages: 966-973
  • DOI: 10.3109/14397595.2014.883055
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Incidence of certified need of care in the long-term care insurance system and its risk factors in the elderly of Japanese population-based cohorts: The ROAD study. (2014)
  • Author(s): Akune T, Muraki S, Oka H, Tanaka S, Kawaguchi H, Tokimura F, Yoshida H, Suzuki T, Nakamura K, Yoshimura N
  • Journal Title: Geriatr Gerontol Int Volume: 14 Issue: 3 Pages: 695-701
  • DOI: 10.1007/s00776-014-0537-z
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Incidence of certified need of care in the long-term care insurance system and its risk factors in the elderly of Japanese population-based cohorts: The ROAD study. (2014)
  • Author(s): Akune T, Muraki S, Oka H, Tanaka S, Kawaguchi H, Tokimura F, Yoshida H, Suzuki T, Nakamura K, Yoshimura N.
  • Journal Title: Geriatr Gerontol Int Volume: in press Issue: 3 Pages: 695-701
  • DOI: 10.1111/ggi.12155
  • Peer Reviewed / Open Access
• [Journal Article] Prevalence, incidence and progression of lumbar spondylosis by gender and age strata. (2014)
  • Author(s): Muraki S, Yoshimura N, Akune T, Tanaka S, Takahashi I, Fujiwara S
  • Journal Title: Mod Rheumatol Volume: 24 Issue: 4 Pages: 657-661
  • DOI: 10.3109/14397595.2013.843761
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Prevalence of knee pain, lumbar pain and its coexistence in Japanese men and women : The Longitudinal Cohorts of Motor System Organ (LOCOMO) study (2013)
  • Author(s): Yoshimura N, Akune T, Fujiwara S, Shimizu Y, Yoshida H, Omori G, Sudo A, Nishiwaki Y, Yoshida M, Shimokata H, Suzuki T, Muraki S, Oka H, Nakamura K
  • Journal Title: J Bone Miner Metab Volume: 32 Issue: 5 Pages: 524-532
  • DOI: 10.1007/s00774-013-0522-1
  • Peer Reviewed / Open Access
• [Presentation] びまん性特発性骨増殖症と腰痛の関連 (2017)
  • Author(s): 籠谷 良平, 吉田 宗人, 村木 重之, 岡 敬之, 橋爪 洋, 山田 宏, 阿久根 徹, 吉村 典子
  • Organizer: 第46回日本脊椎脊髄病学会学術集会
• [Presentation] 一般住民におけるRA関連血清マーカーの陽性率および骨粗鬆症、変形性関節症との関連 The ROAD study (2017)
  • Author(s): 児玉 理恵, 村木 重之, 飯高 世子, 田中 栄, 岡 敬之, 川口 浩, 中村 耕三, 阿久根 徹, 吉村 典子
  • Organizer: 第90回日本整形外科学会学術総会
• [Presentation] 寛骨臼形成不全の疫学 有病率と股関節痛との関連 (2017)
  • Author(s): 飯高 世子, 村木 重之, 岡 敬之, 児玉 理恵, 田中 栄, 川口 浩, 中村 耕三, 阿久根 徹, 吉村 典子
  • Organizer: 第35回日本骨代謝学会学術集会
• [Presentation] 変形性股関節症と職業との関連 (2017)
  • Author(s): 飯高 世子, 村木 重之, 岡 敬之, 堀井 千彬, 田中 栄, 川口 浩, 中村 耕三, 阿久根 徹, 吉村 典子
  • Organizer: 第19回日本骨粗鬆症学会
• [Presentation] 椎間板変性と再生医療 一般住民コホートにおけるTHBS2と椎間板変性との相関解析 (2017)
  • Author(s): 出口 剛士, 橋爪 洋, 中島 正宏, 寺口 真年, 阿久根 徹, 山田 宏, 田中 栄, 吉村 典子, 野島 正寛, 池川 志郎, 吉田 宗人
  • Organizer: 第32回日本整形外科学会基礎学術集会
• [Presentation] サルコペニアと骨粗鬆症を合併した有病者の特徴 ROAD studyより (2016)
  • Author(s): 吉村 典子, 村木 重之, 岡 敬之, 川口 浩, 中村 耕三, 阿久根 徹, 田中 栄
  • Organizer: 第34回日本骨祖鬆症学会
  • Place of Presentation: 仙台勝山館（仙台市）
  • Year and Date: 2016-10-06
• [Presentation] わが国における臼蓋形成不全の有病率 The ROAD study (2016)
  • Author(s): 飯高 世子, 村木 重之, 岡 敬之, 児玉 理恵, 田中 栄, 川口 浩, 中村 耕三, 阿久根 徹, 吉村 典子
  • Organizer: 第89回日本整形外科学会学術総会
  • Place of Presentation: パシフィコ横浜（横浜市）
  • Year and Date: 2016-05-12
• [Presentation] 股関節における関節裂隙幅およびCE角と股関節痛との関連 The ROAD study (2016)
  • Author(s): 飯高 世子, 村木 重之, 岡 敬之, 児玉 理恵, 田中 栄, 川口 浩, 中村 耕三, 阿久根 徹, 吉村 典子
  • Organizer: 第89回日本整形外科学会学術総会
  • Place of Presentation: パシフィコ横浜（横浜市）
  • Year and Date: 2016-05-12
• [Presentation] びまん性特発性骨増殖症の有病率と脊椎矢状面アライメントとの関連 population-based cohort (2016)
  • Author(s): 籠谷 良平, 吉田 宗人, 村木 重之, 岡 敬之, 橋爪 洋, 山田 宏, 筒井 俊二, 浅井 宣樹, 阿久根 徹, 吉村 典子
  • Organizer: 第45回日本脊椎脊髄病学会学術集会
  • Place of Presentation: 幕張メッセ（千葉市）
  • Year and Date: 2016-04-14
• [Presentation] 非特異的腰痛の基礎と臨床 腰椎単純MRI上の加齢変性所見は腰痛の原因か? The Wakayama Spine Study (2016)
  • Author(s): 橋爪 洋, 吉村 典子, 山田 宏, 岡 敬之, 寺口 真年, 岩橋 弘樹, 佐々木 貴英, 村木 重之, 松平 浩, 阿久根 徹, 川口 浩, 南出 晃人, 中川 幸洋, 中村 耕三, 吉田 宗人
  • Organizer: 第45回日本脊椎脊髄病学会学術集会
  • Place of Presentation: 幕張メッセ（千葉市）
  • Year and Date: 2016-04-14
• [Presentation] 25水酸化ビタミンDと骨粗鬆症：ROAD studyから (2015)
  • Author(s): 吉村典子、村木重之、岡敬之、田中栄、川口浩、中村耕三、阿久根徹
  • Organizer: 第17回日本骨粗鬆症学会
  • Place of Presentation: 広島国際会議場（広島市）
  • Year and Date: 2015-09-17
• [Presentation] びまん性特発性骨増殖症と骨密度およびCTX2との関係 (2015)
  • Author(s): 籠谷良平、吉田宗人、村木重之、岡敬之、橋爪洋、山田宏、寺口真年、阿久根徹
  • Organizer: 第88回日本整形外科学会学術総会
  • Place of Presentation: 神戸国際会議場（神戸市）
  • Year and Date: 2015-05-21
• [Presentation] 日本人の加齢性変化に伴う脊柱矢状面アライメントの検討 (2015)
  • Author(s): 浅井宣樹、筒井俊二、山田宏、橋爪洋、吉田宗人、吉村典子、村木重之、阿久根徹、岡敬之
  • Organizer: 第88回日本整形外科学会学術総会
  • Place of Presentation: 神戸国際会議場（神戸市）
  • Year and Date: 2015-05-21
• [Presentation] 一般住民コホートを用いた全脊柱における椎間板変性の有病率と分布について：The Wakayama Spine Study (2015)
  • Author(s): 寺口真年、吉村典子、橋爪洋、村木重之、山田宏、南出晃人、岡敬之、岡敬之、石元優々、長田圭司、籠谷良平、瀧口登、阿久根徹、川口浩、中村耕三、吉田宗人
  • Organizer: 第88回日本整形外科学会学術総会
  • Place of Presentation: 神戸国際会議場（神戸市）
  • Year and Date: 2015-05-21
• [Presentation] 腰椎椎間板周囲の変化と腰痛の関係―The Wakayama Spine Study― (2015)
  • Author(s): 寺口真年、吉村典子、橋爪洋、村木重之、山田宏、岡敬之、南出晃人、阿久根徹、吉田宗人
  • Organizer: 第88回日本整形外科学会学術総会
  • Place of Presentation: 神戸国際会議場（神戸市）
  • Year and Date: 2015-05-21
• [Presentation] 要介護三大原因の因果関係の検討：ロコモとメタボと認知症―ROADスタディ3年後の追跡― (2014)
  • Author(s): 吉村典子、村木重之、岡敬之、田中栄、川口浩、中村耕三、阿久根徹
  • Organizer: 第16回日本骨粗鬆症学会
  • Place of Presentation: 東京京王プラザホテル（新宿区）
  • Year and Date: 2014-10-23 – 2014-10-25
• [Presentation] 変形性膝関節症における骨棘形成の臨床的意義―ROADスタディ3年追跡調査― (2014)
  • Author(s): 村木重之、阿久根徹、田中栄、岡敬之、川口浩、中村耕三、吉村典子
  • Organizer: 第16回日本骨粗鬆症学会
  • Place of Presentation: 東京京王プラザホテル（新宿区）
  • Year and Date: 2014-10-23 – 2014-10-25
• [Presentation] 手指の変形性関節症の有病率と関連因子の検討―The ROAD study― (2014)
  • Author(s): 児玉理恵、岡敬之、村木重之、田中栄、中村耕三、阿久根徹、吉村典子
  • Organizer: 第16回日本骨粗鬆症学会
  • Place of Presentation: 東京京王プラザホテル（新宿区）
  • Year and Date: 2014-10-23 – 2014-10-25
• [Presentation] 糖尿病と全脊椎における椎間板変性との関係―The Wakayama Spine Study― (2014)
  • Author(s): 寺口真年、吉村典子、橋爪洋、村木重之、山田宏、南出晃人、石元優々、長田圭司、籠谷良平、阿久根徹、吉田宗人
  • Organizer: 第29回日本整形外科学会基礎学術集会
  • Place of Presentation: 鹿児島城山観光ホテル（鹿児島市）
  • Year and Date: 2014-10-09 – 2014-10-10
• [Presentation] びまん性特発性骨増殖症と変形性腰椎症および変形性膝関節症との関連 (2014)
  • Author(s): 籠谷良平、吉田宗人、村木重之、岡敬之、橋爪洋、山田宏、長田圭司、石元優々、寺口真年、阿久根徹、吉村典子
  • Organizer: 第29回日本整形外科学会基礎学術集会
  • Place of Presentation: 鹿児島城山観光ホテル（鹿児島市）
  • Year and Date: 2014-10-09 – 2014-10-10
• [Presentation] ロコモとメタボの因果関係：The ROAD Study 3年間の追跡 (2014)
  • Author(s): 吉村典子、村木重之、岡敬之、田中栄、川口浩、中村耕三、阿久根徹
  • Organizer: 第32回日本骨代謝学会学術集会
  • Place of Presentation: 大阪国際会議場（大阪市）
  • Year and Date: 2014-07-24 – 2014-07-26
• [Presentation] 膝痛やADL障害の発生および消失に対する変形性膝関節症の影響：The ROAD Study 3年間の追跡 (2014)
  • Author(s): 村木重之、阿久根徹、岡敬之、田中栄、川口浩、中村耕三、吉村典子
  • Organizer: 第32回日本骨代謝学会学術集会
  • Place of Presentation: 大阪国際会議場（大阪市）
  • Year and Date: 2014-07-24 – 2014-07-26
• [Presentation] 膝関節、運動機能関連項目における要介護移行リスクおよび高リスク者ピックアップツールの検討 The ROAD Study (2014)
  • Author(s): 阿久根 徹, 村木 重之, 岡 敬之, 田中 栄, 川口 浩, 中村 耕三, 吉村 典子
  • Organizer: 第87回日本整形外科学会学術総会
  • Place of Presentation: 神戸国際会議場（神戸市）
  • Year and Date: 2014-05-22 – 2014-05-27
• [Presentation] サルコペニアは膝痛・腰痛と関連し、中年期運動習慣は老年期サルコペニア有病率の低値と関連する The ROAD Study (2014)
  • Author(s): 阿久根 徹, 村木 重之, 岡 敬之, 田中 栄, 川口 浩, 中村 耕三, 吉村 典子
  • Organizer: 第87回日本整形外科学会学術総会
  • Place of Presentation: 神戸国際会議場（神戸市）
  • Year and Date: 2014-05-22 – 2014-05-25
• [Presentation] 中高年一般住民集団の腰椎X線計測指標における腰痛関連因子の解明 The ROAD Study (2014)
  • Author(s): 阿久根 徹, 岡 敬之, 村木 重之, 田中 栄, 川口 浩, 中村 耕三, 吉村 典子
  • Organizer: 第87回日本整形外科学会学術総会
  • Place of Presentation: 神戸国際会議場（神戸市）
  • Year and Date: 2014-05-22 – 2014-05-25
• [Presentation] 変形性膝関節症の疼痛およびADL障害への影響 ROAD追跡調査より (2014)
  • Author(s): 村木 重之, 阿久根 徹, 岡 敬之, 田中 栄, 川口 浩, 中村 耕三, 吉村 典子
  • Organizer: 第87回日本整形外科学会学術総会
  • Place of Presentation: 神戸国際会議場（神戸市）
  • Year and Date: 2014-05-22 – 2014-05-25
• [Presentation] 腰椎すべりの有病率とその腰痛・腰部脊柱管狭窄症の関係について The Wakayama Spine Study (2014)
  • Author(s): 石元 優々, 吉田 宗人, 山田 宏, 長田 圭司, 橋爪 洋, 村木 重之, 岡 敬之, 阿久根 徹, 吉村 典子
  • Organizer: 第44回日本脊椎脊髄病学会学術集会
  • Place of Presentation: 京都国際会館（京都市）
  • Year and Date: 2014-04-17 – 2014-04-19
• [Presentation] 腰椎椎間板周囲の変化と腰痛の関係 The Wakayama Spine Study (2014)
  • Author(s): 寺口 真年, 吉村 典子, 橋爪 洋, 村木 重之, 山田 宏, 岡 敬之, 南出 晃人, 石元 優々, 長田 圭司, 阿久根 徹, 吉田 宗人
  • Organizer: 第44回日本脊椎脊髄病学会学術集会
  • Place of Presentation: 京都国際会館（京都市）
  • Year and Date: 2014-04-17 – 2014-04-19
• [Remarks] 平成26年度 月例報告
  • URL: http://www.rehab.go.jp/monthly/2014_7.html
• [Remarks] 平成26年度 月例報告
  • URL: http://www.rehab.go.jp/monthly/2014_9.html
• [Remarks] 平成26年度 月例報告
  • URL: http://www.rehab.go.jp/monthly/2014_11.html