| Project/Area Number |
26293389
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (B)
|
| Allocation Type | Partial Multi-year Fund |
|---|
| Section | 一般 |
|---|
| Research Field |
Emergency medicine
|
|---|
| Research Institution | National Cardiovascular Center Research Institute |
|---|
Principal Investigator |
Kamiya Atsunori 国立研究開発法人国立循環器病研究センター, 研究所, 室長 (30324370)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
杉町 勝 国立研究開発法人国立循環器病研究センター, 研究所, 部長 (40250261)
|
|---|
| Co-Investigator(Renkei-kenkyūsha) |
KOBAYASHI KAZUTO 福島県立医科大学, 生体情報伝達研究所生体機能研究部門, 教授 (90211903)
|
|---|
| Project Period (FY) |
2014-04-01 – 2017-03-31
|
| Project Status |
Completed (Fiscal Year 2016)
|
| Budget Amount *help |
¥15,990,000 (Direct Cost: ¥12,300,000、Indirect Cost: ¥3,690,000)
Fiscal Year 2016: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2015: ¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2014: ¥5,850,000 (Direct Cost: ¥4,500,000、Indirect Cost: ¥1,350,000)
|
|---|
| Keywords | 自律神経 / 生物・生体工学 |
|---|
| Outline of Final Research Achievements |
Autonomic nervous system is closely related with various diseases, including cardiovascular diseases. However, therapeutic interventions to autonomic nerves remain to be developed. Based on our basic researches about autonomic nervous system, we developed electrical neural treatment (i.e., cervical vagal stimulation) and actually improved survival rate of heart failure model animals. We increased the quality of this neural treatment, and newly developed genetic neural treatment as alternatives of electrical neural treatment, that is useful to explore and expand target diseases of autonomic neural treatment. In addition, based on our circulatory physiology researches, we developed automated medical drug infusion system as a support of critical care medicine, made a multiple-step safety system for practical application and examined an integration of autonomic neural and circulatory treatments.
|
