| Project/Area Number |
26293444
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Partial Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Fundamental nursing
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| Research Institution | Kanazawa University |
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Principal Investigator |
SUGAMA JUNKO 金沢大学, 新学術創成研究機構, 教授 (00203307)
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| Co-Investigator(Kenkyū-buntansha) |
真田 弘美 東京大学, 医学(系)研究科(研究院), 教授 (50143920)
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| Co-Investigator(Renkei-kenkyūsha) |
YOKOGAWA Masami 金沢大学, 保健学系, 准教授 (80303288)
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| Research Collaborator |
TAWARA Mariko 北陸学院大学短期大学部, 食物栄養学科, 助教
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥13,910,000 (Direct Cost: ¥10,700,000、Indirect Cost: ¥3,210,000)
Fiscal Year 2016: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2015: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2014: ¥5,980,000 (Direct Cost: ¥4,600,000、Indirect Cost: ¥1,380,000)
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| Keywords | 肥満 / 皮膚 / 超音波診断装置 / 酸化ストレス / 前向き観察研究 / スキンケア / 男性 / 運動教室 / 看護工学 / 減量 / 真皮 / 看護技術 |
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| Outline of Final Research Achievements |
The purpose of this study was to clarify the skin changes in overweight and obese Japanese males participated in the 1-year walking program. This study was approved by the Medical Ethics Committee of Kanazawa University (No.430). Subcutaneous thickness was assessed by using the ultrasound device with the 18-MHz frequency and dermal echogenicity was also assessed by ultrasound device with the 20-MHz frequency. Moreover, skin oxidative stress was assessed by measuring the mRNA expression level of heme oxygenase-1 (HO-1) in hair follicles. There were 18 males who successfully lost body weight and 11 of their BMI were equal or less 25. Dermal echogenicity increase was found in 38.8% (7/18) lose weight males’ abdomen images and in 61.1% (11/18) thigh images. HO-1 expression level decrease was found in 66.7% (6/9) lose weight males’ abdomen samples and in 50% (4/88) thigh samples.
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