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Heterogeneity in age-related functional changes in later life and its association with social serucity needs

Research Project

Project/Area Number 26310111
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypePartial Multi-year Fund
Section特設分野
Research Field Neo-Gerontology
Research InstitutionTokyo Metropolitan Geriatric Hospital and Institute of Gerontology

Principal Investigator

SHINKAI Shoji  地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 副所長 (60171063)

Co-Investigator(Kenkyū-buntansha) 谷口 優  地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 研究員 (40636578)
清野 諭  地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 研究員 (50725827)
西 真理子  地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 研究員 (70543601)
天野 秀紀  地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 研究助手 (90260306)
村山 洋史  地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 研究員 (00565137)
北村 明彦  地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 研究部長 (80450922)
Project Period (FY) 2014-07-18 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥16,250,000 (Direct Cost: ¥12,500,000、Indirect Cost: ¥3,750,000)
Fiscal Year 2016: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2015: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2014: ¥6,110,000 (Direct Cost: ¥4,700,000、Indirect Cost: ¥1,410,000)
Keywords生活機能 / 高齢者 / 加齢変化 / 個人差 / 社会保障ニーズ / 類型化 / 心身機能
Outline of Final Research Achievements

This study was the first to show the heterogeneity of age-related functional change in later life. 36.3% and 40.1% of older adults remained independent until 85 and 80 years of age on the average in terms of higher order functional capacity as assessed by TMIG-IC. On the other hand, 17.4% of older adults became frail(as defined by TMIG-IC less than 10 scores) around the age of 75 years and 6.1% of those were already frail at the age of 65 years. The former two groups consumed more health care cost with advancing ages, but consumed very low cost of long-term care until 90 years of age. The total cost of health care and long-term care in the two groups did not increase so much and remained relatively low even at very advanced ages. In the super-aged society, Japan, we can expect more potential of productivity for 75% of older population. On the other hand, one fourth of older population had high social security need even in young old ages and need the special attention.

Report

(4 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Annual Research Report
  • 2014 Annual Research Report
  • Research Products

    (40 results)

All 2017 2016 2015 2014

All Journal Article (23 results) (of which Int'l Joint Research: 5 results,  Peer Reviewed: 22 results,  Open Access: 11 results,  Acknowledgement Compliant: 9 results) Presentation (17 results) (of which Int'l Joint Research: 8 results,  Invited: 9 results)

  • [Journal Article] Changes in health behaviors and the trajectory of body mass index among older Japanese: a 19-year longitudinal study2017

    • Author(s)
      Murayama H, Liang J, Shaw BA, Botoseneanu A, Kobayashi E, Fukaya T, Shinkai S
    • Journal Title

      Geriatr Gerontol Int

      Volume: 印刷中 Issue: 11 Pages: 2008-2016

    • DOI

      10.1111/ggi.13008

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Mini-Mental State Examination Score Trajectories and Incident Disabling Dementia Among Community-Dwelling Older Japanese2017

    • Author(s)
      Taniguchi Y, Kitamura A, Murayama H, Amano H, Shinozaki T, Yokota I, Seino S, Nofuji Y, Nishi M, Yokoyama Y, Matsuyama Y, Fujiwara Y, Shinkai S
    • Journal Title

      Geriatr Gerontol Int

      Volume: 印刷中 Issue: 11 Pages: 1928-1935

    • DOI

      10.1111/ggi.12996

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Gait performance trajectories and incidence of dementia2017

    • Author(s)
      Taniguchi Y, Kitamura A, Seino S, Murayama H, Amano H, Nofuji Y, Nishi M, Yokoyama Y, Shinozaki T, Yokota I, Matsuyama Y, Fujiwara Y, Shinkai S
    • Journal Title

      J Am Med Dir Assoc

      Volume: 印刷中 Issue: 2 Pages: 192.e13-192.e20

    • DOI

      10.1016/j.jamda.2016.10.015

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Albumin, hemoglobin, and the trajectory of cognitive function in community-dwelling older Japanese: a 13-year longitudinal study2017

    • Author(s)
      Murayama H, Shinkai S, Nishi M, Taniguchi Y, Amano H, Seino S, Yokoyama Y, Yoshida H, Fujiwara Y, Ito H
    • Journal Title

      J Prev Alzheimer's Dis

      Volume: 印刷中

    • Related Report
      2016 Annual Research Report
  • [Journal Article] Dietary variety and decline in lean mass and physical performance in community-dwelling older Japanese: A 4-year follow-up study.2016

    • Author(s)
      Yokoyama Y, Nishi M, Murayama H, Amano H, Taniguchi Y, Nofuji Y, Narita M, Matsuo E, Seino S, Kawano Y, Shinkai S.
    • Journal Title

      Journal of Nutrition, Health and Aging

      Volume: 印刷中 Issue: 1 Pages: 11-16

    • DOI

      10.1007/s12603-016-0726-x

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Prospective study of trajectories of physical performance and mortality among community-dwelling older Japanese2016

    • Author(s)
      Taniguchi Y, Fujiwara Y, Murayama H, Yokota I, Matsuo E, Seino S, Nofuji Y, Nishi M, Matsuyama Y, Shinkai S
    • Journal Title

      J Gerontol A Biol Sci Med Sci

      Volume: 71 Pages: 1492-1499

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Association of dietary variety with body composition and physical function in community-dwelling elderly Japanese.2016

    • Author(s)
      Yokoyama Y, Nishi M, Murayama H, Amano A, Taniguchi Y, Nofuji Y, Narita M, Matsuo E, Seino S, Kawano Y, Shinkai S.
    • Journal Title

      Journal of Nutrition, Health and Aging

      Volume: 印刷中 Issue: 7 Pages: 691-696

    • DOI

      10.1007/s12603-015-0632-7

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Associations of Walking Speed, Grip Strength, and Standing Balance with Total and Cause-Specific Mortality in a General Population of older Japanese2016

    • Author(s)
      Nofuji Y, Shinkai S, Taniguchi Y, Amano H, Nishi M, Murayama H, Fujiwara Y, Suzuki T
    • Journal Title

      J Am Med Dir Assoc

      Volume: 7 Issue: 2 Pages: 184-184

    • DOI

      10.1016/j.jamda.2015.11.003

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Public health approach to preventing frailty in the community and its effect on healthy aging in Japan2016

    • Author(s)
      Shinkai S, Yoshida H, Taniguchi Y, Murayama H, Nishi M, Amano H, Nofuji Y, Seino S, Fujiwara Y
    • Journal Title

      Geriatr Gerontol Int

      Volume: 16 Issue: S1 Pages: 87-97

    • DOI

      10.1111/ggi.12726

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Associations of walking speed, grip strength, and standing balance with total and cause-specific mortality in a general population of Japanese elders2016

    • Author(s)
      Nofuji Y, Shinkai S, Taniguchi Y, Amano H, Nishi M, Murayama H, Fujiwara Y, Suzuki T
    • Journal Title

      Journal of American Directors Association

      Volume: 17

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Public health approach to preventing frailty in the community and its effects on healthy aging in Japan2016

    • Author(s)
      Shinkai S, Yoshida H, Taniguchi Y, Murayama H, Nishi M, Amano H, Nofuji Y, Seino S, Fujiwara Y
    • Journal Title

      Geriatrics Gerontology International

      Volume: 16 (Suppl.1) Pages: 87-97

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] 高齢者向けの集団健診が余命および健康余命に及ぼす影響-草津町介護予防事業10年間の効果評価の試み-2016

    • Author(s)
      西真理子, 吉田裕人, 藤原佳典, 深谷太郎, 天野秀紀, 熊谷修, 渡辺修一郎, 村山洋史, 谷口優, 干川なつみ, 土屋由美子, 新開省二
    • Journal Title

      厚生の指標

      Volume: 63 (2) Pages: 2-11

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Reference values and age differences in body composition of community-dwelling older Japanese men and women: A pooled analysis of four cohort studies2015

    • Author(s)
      Seino S, Shinkai S, Iijima K, Obuchi S, Fujiwara Y, Yoshida H, Kawai H, Nishi M, Murayama H, Taniguchi Y, Amano H, Takahashi R
    • Journal Title

      PLos ONE

      Volume: 10 Issue: 7 Pages: e0131975-e0131975

    • DOI

      10.1371/journal.pone.0131975

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Trajectories of body mass index and their associations with morality among older Japanese: Do they differ from Western populations?2015

    • Author(s)
      Murayama H, Liang J, Bennett JM, Shaw BA, Botoseneanu A, Kobayashi E, Fukaya T, Shinkai S
    • Journal Title

      American Journal of Epidemiology

      Volume: 182 Issue: 7 Pages: 597-605

    • DOI

      10.1093/aje/kwv107

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Longitudinal association between neighborhood cohesion and depressive mood in old age: A Japanese prospective study2015

    • Author(s)
      Murayama H, Nishi M, Nofuji Y, Matsuo E, Taniguchi Y, Amano H, Yokoyama Y, Fujiwara Y, Shinkai S
    • Journal Title

      Health & Place

      Volume: 34 Pages: 270-278

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Cardiometabolic risk, socio-psychological factors, and trajectory of grip strength among older adults2015

    • Author(s)
      Botoseneanu A, Bennett JM, Nyquist L. Shinkai S, Fujiwara Y, Yoshida H, Aiello A, Cigolle CT, Liang J
    • Journal Title

      Journal of Aging and Health

      Volume: 27 Issue: 7 Pages: 1123-1146

    • DOI

      10.1177/0898264315577587

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Prospective Study of Arterial Stiffness and Subsequent Cognitive Decline Among Community-Dwelling Older Japanese2015

    • Author(s)
      Yu Taniguchi、Yoshinori Fujiwara、Mariko Nishi、Hiroshi Murayama、Yu Nofuji、Satoshi Seino、Rika Tajima、Yutaka Matsuyama、Shoji Shinkai.
    • Journal Title

      Journal of Epidemiology

      Volume: 25 Issue: 9 Pages: 592-599

    • DOI

      10.2188/jea.JE20140250

    • NAID

      130005096831

    • ISSN
      0917-5040, 1349-9092
    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] 地域在住高齢者に対する虚弱予防教室による虚弱および食習慣の改善効果2015

    • Author(s)
      川畑輝子, 武見ゆかり, 村山洋史, 西真理子, 清水由美子, 成田美紀, 金美芝, 新開省二
    • Journal Title

      日本公衆衛生学雑誌

      Volume: 62 Pages: 169-181

    • NAID

      130005076411

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Are neighborhood bonding and bridging social capital protective against depressive mood in old age? A multilevel analysis in Japan2015

    • Author(s)
      Murayama H, Nofuji Y, Matsuo E, Nishi M, Taniguchi Y, Fujiwara Y, Shinkai S
    • Journal Title

      Social Science and Medicine

      Volume: 124 Pages: 171-179

    • DOI

      10.1016/j.socscimed.2014.11.042

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Does social support buffer the effect of financial strain on the trajectory of smoking in older Japanese? A 19-year longitudinal study2015

    • Author(s)
      Murayama, H., Bennett, J. M., Shaw, B. A., Liang, J., Krause, N., Kobayashi, E., Fukaya, T., & Shinkai, S.
    • Journal Title

      Journal of Gerontology Series B: Psychological Sciences and Social Sciences

      Volume: 70(3) Issue: 3 Pages: 367-376

    • DOI

      10.1093/geronb/gbt103

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Reference Values and Age and Sex Differences in Physical Performance Measures for Community-Dwelling Older Japanese: A Pooled Analysis of Six Cohort Studies2014

    • Author(s)
      Seino S, Shinkai S, Fujiwara Y, Obuchi S, Yoshida H, Hirano H, Kim HK, Ishizaki T, Takahashi R; TMIG-LISA Research Group
    • Journal Title

      PLOS ONE

      Volume: 9 Issue: 6 Pages: e99487-e99487

    • DOI

      10.1371/journal.pone.0099487

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Nutritional biomarkers and subsequent cognitive decline among community-dwelling older Japanese: A prospective study.2014

    • Author(s)
      Taniguchi Y, Shinkai S, et al (他5名)
    • Journal Title

      Journal of Gerontology: Biological Sciences & Medical Sciences

      Volume: 印刷中 Issue: 10 Pages: 1276-1283

    • DOI

      10.1093/gerona/glt286

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Regional cerebral glucose metabolism and gait speed in healthy community-dwelling older women.2014

    • Author(s)
      Sakurai R, Fujiwara Y, Yasunaga M, Takeuchi R, Murayama Y, Ohba H, Sakuma N, Suzuki H, Oda K, Sakata M, Toyohara J, Ishiwata K, Shinkai S, Ishii K
    • Journal Title

      J Gerontol A Biol Sci Med Sci

      Volume: 69 Issue: 12 Pages: 1519-27

    • DOI

      10.1093/gerona/glu093

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Presentation] Short and long-term effects of a multifactorial intervention for pre-frail and frail elderly on their functional health: a randomized, controlled, crossover trial within a cohort study2017

    • Author(s)
      Shinkai S, Seino S
    • Organizer
      The 12th International Symposium on Geriatrics and Gerontology entitled "Frailty and dementia- From its pathogenesis to prevention and treatment-"
    • Place of Presentation
      Obu, Aichi, Japan
    • Year and Date
      2017-03-04
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Knowledge transition about frailty prevention- From prevention to practice2016

    • Author(s)
      Shinkai S
    • Organizer
      Second Mexico-Japan Meeting on Healthy Ageing
    • Place of Presentation
      Mexico City, Mexico
    • Year and Date
      2016-06-20
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Community based strategy for preventing frailty2016

    • Author(s)
      Shinkai S, Seino S
    • Organizer
      International Seminar on Frailty Cohort & Intervention Study
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2016-05-16
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] How to build an age-friendly city through social participation2016

    • Author(s)
      Shinkai S
    • Organizer
      Conference for Age-Friendly City Strategies of Busan
    • Place of Presentation
      Busan, Korea
    • Year and Date
      2016-05-12
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] A public health approach for frailty prevention in community and its impact upon healthy aging in Japan2015

    • Author(s)
      Shinkai S, Nishi M, Taniguchi Y, Murayama H, Amano H, Nofuji Y, Seino S, Fujiwara H, Ikeuchi T
    • Organizer
      The 68th Annual Scientific Meeting of Gerontological Society of America (GSA)
    • Place of Presentation
      Orland, USA
    • Year and Date
      2015-11-18
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Gerontology in Japan and state-of-art projects in Japan.2015

    • Author(s)
      Shinkai S, Ikeuchi T
    • Organizer
      Japan-UK Reseach and Education Network for Knowledge Economy Initiatives Workshop at Osaka University
    • Place of Presentation
      Osaka University (Suita, Japan)
    • Year and Date
      2015-10-23
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Public health approach for frailty prevention in a community and its impact upon healthy aging: A 10-year community intervention in Japan2015

    • Author(s)
      Shinkai S
    • Organizer
      The 21th Congress of the International Association of Gerontology and Geriatrics (IAGG)
    • Place of Presentation
      Chiang Mai, Thailand
    • Year and Date
      2015-10-19
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 草津町における介護予防共同研究事業からみた高齢者保健の課題2015

    • Author(s)
      新開省二, 吉田裕人, 藤原佳典, 天野秀樹, 西真理子, 村山洋史, 谷口優, 野藤悠, 清野諭, 岡部たづる, 干川なつみ
    • Organizer
      第74回日本公衆衛生学会総会
    • Place of Presentation
      長崎ブリックホールほか(長崎県・長崎市)
    • Year and Date
      2015-10-04
    • Related Report
      2015 Annual Research Report
  • [Presentation] 地域における介護予防10年間の取り組み、その成果と課題2015

    • Author(s)
      新開省二
    • Organizer
      第70回日本体力医学会大会
    • Place of Presentation
      和歌山県民文化会館ほか(和歌山県・和歌山市)
    • Year and Date
      2015-09-18
    • Related Report
      2015 Annual Research Report
  • [Presentation] Good nutrition and physical function as a key component for healthy aging: Results from cohort studies on Japanese older adults2015

    • Author(s)
      Shinkai S
    • Organizer
      The 12th Asian Congress of Nutrition
    • Place of Presentation
      Pacifico Yokohama (Yokohama, Japan)
    • Year and Date
      2015-05-14
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Prevention of frailty and healthy aging: a 10-year community intervention in Japan2015

    • Author(s)
      Shinkai S
    • Organizer
      Mexico-Japan Encounter on Active and Healthy Aging
    • Place of Presentation
      Mexico City, Mexico
    • Year and Date
      2015-02-10
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] A prospective study on nutritional state and active life expectancy in a general population of older Japanese2015

    • Author(s)
      40.Shinkai S, Nishi M, Taniguchi Y, Amano H, Murayama H, Nofuji Y, Seino S, Narita M, Matsuo E, Yokoyama Y, Fujiwara Y
    • Organizer
      第25回日本疫学会総会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-01-21 – 2015-01-23
    • Related Report
      2014 Annual Research Report
  • [Presentation] Physical, nutritional and social aspects of healthy aging in Japan: Longitudinal Interdisciplinary Study on Aging (TMIG-LISA)2014

    • Author(s)
      Shinkai S
    • Organizer
      "Healthy Aging" symposium in 2014 Global Health Forum in Taiwan
    • Place of Presentation
      Taipei, Taiwan
    • Year and Date
      2014-11-30 – 2014-12-01
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] Association between dietary variety and body composition and physical function in community-dwelling elderly Japanese people2014

    • Author(s)
      4.Yokoyama Y, Nishi M, Murayama H, Amano H, Taniguchi Y, Narita M, Kawano Y, Shinkai S
    • Organizer
      The Gerontological Society of America 67th Annual Scientific Meeting
    • Place of Presentation
      Washington DC, USA
    • Year and Date
      2014-11-05 – 2014-11-09
    • Related Report
      2014 Annual Research Report
  • [Presentation] Trajectories of Body Mass Index and All-cause Mortality: Findings from the National Survey of the Japanese Elderly2014

    • Author(s)
      5.Murayama H, Liang J, Bennett JM, Shaw BA, Botoseneanu A, Kobayashi E, Akiyama H, Shinkai S
    • Organizer
      The Gerontological Society of America 67th Annual Scientific Meeting
    • Place of Presentation
      Washington DC, USA
    • Year and Date
      2014-11-05 – 2014-11-09
    • Related Report
      2014 Annual Research Report
  • [Presentation] Risk factors of Cognitive Decline in Japanese Commurity Dwellers : a 10-Year Cohort Study2014

    • Author(s)
      7.Amano H, Yoshida H, Fujiwara Y, Nishi M, Murayama H, Taniguchi Y, Nofuji Y, Shinkai S
    • Organizer
      The Gerontological Society of America 67th Annual Scientific Meeting
    • Place of Presentation
      Washington DC, USA
    • Year and Date
      2014-11-05 – 2014-11-09
    • Related Report
      2014 Annual Research Report
  • [Presentation] Promoting healthy aging. A 10-year community intervention for frailty prevention and its impact upon healthy aging in Japan2014

    • Author(s)
      Shinkai S
    • Organizer
      New Frontiers in Research on Aing and Health, 2014 Joint Symposium of the Graduate School & Institute on Aging, Ajou University School of Medicine
    • Place of Presentation
      Suwon, Korea
    • Year and Date
      2014-09-20
    • Related Report
      2014 Annual Research Report
    • Invited

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Published: 2014-09-09   Modified: 2018-03-22  

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