| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2016: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2015: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2014: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
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| Outline of Final Research Achievements |
The inhibition technology against biofilm formation and biofouling has been developed with controlling the activities of complex microbes.
N-acyl homoserine lacton (AHL), a signal molecule of quorum sensing in gram negative bacteria, producing bacteria and also AHL degradation bacteria were isolated from the same biofilm sample. Bacterial biofilm formation and biofouling are regulated by QS. For these reasons, quorum quenching (QQ) bacteria and enhancement there QQ activities should be useful for inhibition of biofilm formation and biofouling under complex microbes condition.
Moreover, several QQ techniques to inhibit biofilm formation have been developed.
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