Development of methods to determine the energy requirement of adults with motor disabilities: the double-labeled water method and indirect calorimetry system

• Project/Area Number: 26350151
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Eating habits
• Research Institution: Ibaraki Prefectural University of Health Science
• Principal Investigator: IWASAKI NOBUAKI 茨城県立医療大学, 保健医療学部, 教授 (70251006)
• Co-Investigator(Kenkyū-buntansha): 河野 豊 茨城県立医療大学, 保健医療学部, 教授 (10392200) ; 沼野 智一 首都大学東京, 人間健康科学研究科, 准教授 (10399511) ; 大和田 浩子 山形県立米沢栄養大学, 健康栄養学部, 教授 (90316414)
• Research Collaborator: TAKADA Kazuoko 国立健康・栄養研究所, 室長 (80202951)
• Project Period (FY): 2014-04-01 – 2018-03-31
• Project Status: Completed (Fiscal Year 2017)
• Budget Amount: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000); Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000); Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000); Fiscal Year 2014: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
• Keywords: エネルギー代謝 / 運動機能障害 / 間接熱量測定装置 / 通気性フード / 二重標識水法 / DLW法 / エネルギー代謝量 / 開放性キャノピー / 開放型キャノピー

Outline of Final Research Achievements

We aimed to establish a handy technique for calculating individual energy requirements in both children and elderly people with motor disabilities. We developed a new ventilated hood for an indirect calorimetry system that could be used in subjects over a wide range of physical sizes and even in those with a tracheostomy, and could be associated with only minor senses of incompatibility or unpleasant experiences. The resting metabolic rate (RMR) was measured using this indirect calorimetry system and total energy expenditure (TEE) calculated by the double-labeled water method, regarded as the most accurate measurement procedure available at present. Total energy intake was also calculated using dietary records and the RMR and TEE values then compared. The study showed it was possible to determine an individual’s energy requirement with a reasonable degree of accuracy using this indirect calorimetry system.

Research Products

• [Journal Article] 重症心身障害児(者)におけるフードを用いたエネルギー代謝量の測定 (2015)
  • Author(s): 岩崎信明、中山純子、稲田恵美、絹笠英世、中山智博、伊藤達夫
  • Journal Title: 脳と発達 Volume: 47 Pages: 53-54
  • NAID: 130005005753
  • Peer Reviewed
• [Presentation] 気管切開を有する重症心身障害児におけるエネルギー代謝量の測定 (2017)
  • Author(s): 岩崎信明，中山純子，中山智博，大黒春夏
  • Organizer: 第6回茨城小児神経懇話会
• [Presentation] Energy requirement assessed by double-labeled water method in individuals with quadriplegic cerebral palsy (GMFCS level V) (2017)
  • Author(s): Iwasaki N, Takata IK, Nakayama J, Nakayama T, Maeda T, Ohguro H, Ohwasa H
  • Organizer: 14th Asia and oceanian congress of child neurology
  • Int'l Joint Research
• [Presentation] 重度心身障害児（者）における改良した希釈法を用いたエネルギー代謝量の測定 (2017)
  • Author(s): 岩崎信明、中山純子、中山智博、大黒春夏、新健治
  • Organizer: 第59回日本小児神経学会
• [Presentation] 臨床の現場でのDLW法の実際 (2014)
  • Author(s): 岩崎信明
  • Organizer: DLW Workshop 2014
  • Place of Presentation: Tokyo,JAPAN
  • Year and Date: 2014-10-13 – 2014-10-14
  • Invited
• [Presentation] 障害児・者におけるDLW法の実際 (2014)
  • Author(s): 大和田浩子
  • Organizer: DLW Workshop 2014
  • Place of Presentation: Tokyo,JAPAN
  • Year and Date: 2014-10-13 – 2014-10-14
  • Invited