Development of phase-contrast CT reconstruction algorithm for biological samples including hard tissues
| Project/Area Number |
26350494
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Biomedical engineering/Biomaterial science and engineering
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| Research Institution | Yamagata University |
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Principal Investigator |
Tetsuya Yuasa 山形大学, 大学院理工学研究科, 教授 (30240146)
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| Co-Investigator(Renkei-kenkyūsha) |
SUNAGUCHI Naoki 名古屋大学, 大学院医学系研究科, 准教授 (60536481)
ANDO Masami 東京理科大学, 総合研究機構, 教授 (30013501)
ICHIHARA Shu 名古屋医療センター, 臨床研究センター, 室長 (30426499)
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| Project Period (FY) |
2014-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | 位相コントラスト / コンピューテッド・トモグラフィ / X線角度アナライザー / アーチファクト / 放射光X線 / 屈折コントラスト / Ｘ線角度アナライザー / 放射光Ｘ線 |
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| Outline of Final Research Achievements |
Phase-contrast computed tomography using Laue-type angular analyzer can non-destructively delineate biological soft tissues samples at a high contrast and a spatial resolution of a few tens of micron. However, for samples including hard tissues such as bones and calcified plaques the imaging method suffers from deterioration of reconstructed image quarity by remarkable streak artifacts caused by hard tissues. In this research, we devised a novel reconstruction algorithm to improve the image quality by suppressing the artifacts. We demonstrated the efficacy of the proposed method by computer simulation and experiments using biological samples including hard tissues.
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Report
(5 results)
Research Products
(29 results)
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[Journal Article] Evaluation of retinal nerve fiber layer defect using wide-field en-face swept-source OCT images by applying the inner limiting membrane flattening2017
Author(s)
Naoki Miura, Kazuko Omodaka, Koudai Kimura, Akiko Matsumoto, Tsutomu Kikawa, Seri Takahashi, Naoko Takada, Hidetoshi Takahashi, Kazuichi Maruyama, Masahiro Akiba, Tetsuya Yuasa, Toru Nakazawa
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Journal Title
PloS one
Volume: 12
Issue: 10
Pages: e0185573-e0185573
DOI
Related Report
Peer Reviewed / Open Access
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[Journal Article] Evaluating retinal vessel diameter with optical coherence tomography in normal-tension glaucoma patients2017
Author(s)
Takeshi Yabana, Yukihiro Shiga, Ryo Kawasaki, Kazuko Omodaka, Hidetoshi Takahashi, Koudai Kimura, Kyosuke Togashi, Takaaki Horii, Kei Sasaki, Testuya Yuasa, Toru Nakazawa
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Journal Title
Japanese journal of ophthalmology
Volume: 61
Issue: 5
Pages: 378-387
DOI
Related Report
Peer Reviewed
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[Journal Article] Dark-Field Imaging: Recent developments and potential clinical2016
Author(s)
M. Ando, N. Sunaguchi , D. Shimao, A. Pan, T. Yuasa , K. Mori, Y. Suzuki, G. Jin, J. K. Kim, J. H. Lim, S. J. Seo, S. Ichihara, N. Ohura, R. Gupta
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Journal Title
Physica Medica
Volume: 32
Issue: 12
Pages: 1801-1812
DOI
Related Report
Peer Reviewed / Int'l Joint Research
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[Journal Article] Synchrotron-based phase-contrast images of zebrafish and its anatomical structures2014
Author(s)
Venkateswara Rao Donepudi, Bhaskaraiah Melumai, Balasaidulu Thallapaka, Konam Sandeep, Roberto Cesareo, Antonio Brunetti, Zhong Zhong, Takao Akatsuka, Tetsuya Yuasa, Tohoru Takeda, Giovanni E Gigante
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Journal Title
The European Physical Journal Applied Physics
Volume: 67
Issue: 2
Pages: 20701-20701
DOI
Related Report
Peer Reviewed
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