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Effect of ultrasonic irradiation on bacterial biofilms

Research Project

Project/Area Number 26350543
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Medical systems
Research InstitutionJichi Medical University

Principal Investigator

Koibuchi Harumi  自治医科大学, 医学部, 講師 (20382848)

Co-Investigator(Kenkyū-buntansha) 藤井 康友  京都大学, 医学研究科, 教授 (00337338)
Project Period (FY) 2014-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Keywords超音波 / 細菌 / バイオフィルム / 表皮ブドウ球菌 / カテーテル関連血流感染症 / 中心静脈カテーテル / 検査 / 治療
Outline of Final Research Achievements

Ultrasonic irradiation (US) can decrease the amount of Staphylococcus epidermidis (S. epidermidis) biofilm when the duration of US irradiation is sufficiently long even if the acoustic intensity is low.
In addition, US irradiation can inhibit the formation of S.epidermidis biofilm. And the inhibitory effect of US irradiation at the early stage can reduced the biofilm formation even if the duration time of US irradiation was short.The inhibitory effect of duplicated irradiation on biofilm effect had nearly twice as high as single irradiation, however, the single irradiation at early stage can also reduce the biofilm formation by 17.9 %.

Report

(5 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • 2014 Research-status Report
  • Research Products

    (9 results)

All 2018 2017 2016 2015

All Journal Article (1 results) (of which Peer Reviewed: 1 results,  Open Access: 1 results) Presentation (8 results) (of which Int'l Joint Research: 1 results)

  • [Journal Article] Effect of ultrasonic irradiation on bacterial biofilms2018

    • Author(s)
      Harumi Koibuchi
    • Journal Title

      Journal of Medical Ultrasonics

      Volume: 45 Pages: 25-29

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Presentation] 超音波エネルギーが細菌のバイオフィルムに及ぼす影響2017

    • Author(s)
      鯉渕 晴美
    • Organizer
      日本超音波医学会関東甲信越地方会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 超音波エネルギーが細菌のバイオフィルムに及ぼす影響2017

    • Author(s)
      鯉渕 晴美
    • Organizer
      日本臨床検査医学会学術集会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Inhibitory effect of ultrasonic irradiation on bacterial biofilm formation2017

    • Author(s)
      鯉渕 晴美
    • Organizer
      International Conference on Biomedical Ultrasound
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 超音波エネルギーが細菌のバイオフィルムに与える影響(第2報)2016

    • Author(s)
      鯉渕 晴美
    • Organizer
      日本超音波医学会
    • Place of Presentation
      国立京都国際会館(京都,京都市)
    • Year and Date
      2016-05-27
    • Related Report
      2016 Research-status Report
  • [Presentation] 超音波エネルギーが細菌のバイオフィルに与える影響ー第2報ー2016

    • Author(s)
      鯉渕 晴美
    • Organizer
      日本超音波医学会
    • Place of Presentation
      京都
    • Year and Date
      2016-05-27
    • Related Report
      2015 Research-status Report
  • [Presentation] Staphylococcus epidermidis のバイオフィルム作成方法と超音波エネルギーが細菌のバイオフィルムに与える影響2015

    • Author(s)
      鯉渕 晴美
    • Organizer
      日本臨床検査医学会
    • Place of Presentation
      岐阜
    • Year and Date
      2015-11-19
    • Related Report
      2015 Research-status Report
  • [Presentation] 超音波エネルギーが細菌のバイオフィルム破壊に及ぼす影響2015

    • Author(s)
      鯉渕 晴美
    • Organizer
      日本超音波医学会
    • Place of Presentation
      東京
    • Year and Date
      2015-05-22 – 2015-05-24
    • Related Report
      2014 Research-status Report
  • [Presentation] 超音波エネルギーが細菌のバイオフィルムに与える影響2015

    • Author(s)
      鯉渕 晴美
    • Organizer
      日本超音波医学会
    • Place of Presentation
      東京
    • Year and Date
      2015-05-22
    • Related Report
      2015 Research-status Report

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Published: 2014-04-04   Modified: 2019-03-29  

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