Deep rTMS on medial cortex for acute stroke patients
| Project/Area Number |
26350589
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Rehabilitation science/Welfare engineering
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| Research Institution | International University of Health and Welfare |
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Principal Investigator |
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Fiscal Year 2016: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2015: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | 経頭蓋磁気刺激 / 脳卒中 / リハビリテーション / 下肢麻痺 / 自発性 / 高次脳機能障害 / 片麻痺 / アパシー / 急性期 / 非侵襲的脳刺激 |
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| Outline of Final Research Achievements |
No study has examined the usefulness of repetitive transcranial magnetic stimulation (rTMS) for lower limb hemiparesis and post stroke apathy in patients with acute stroke. 21 acute stroke patients were randomly assigned into two groups: the high frequency (HF)-rTMS group and the sham stimulation group. Patients received rTMS for 5 consecutive days. The improvement in paretic leg motor function was significant in the HF-rTMS group.
13 chronic stroke patients were assigned randomly to two groups: rTMS group and sham stimulation group. The patients received 5 sessions of either HF-rTMS over the region spanning from the dorsal anterior cingulate cortex (dACC) to medial prefrontal cortex (mPFC) or sham stimulation for 5 days. The severity of apathy was significantly improved in the rTMS group. This rTMS application was also safe and feasible for recovery of apathy in acute phase.
Application of rTMS has potential to be a new rehabilitation therapy for patients in the acute phase of stroke.
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Report
(4 results)
Research Products
(15 results)
