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Development of gustatory BMI using common marmoset brain.

Research Project

Project/Area Number 26350592
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Rehabilitation science/Welfare engineering
Research InstitutionKanazawa Medical University

Principal Investigator

SONOMURA Takahiro  金沢医科大学, 医学部, 講師 (40347092)

Co-Investigator(Kenkyū-buntansha) 古田 貴寛  京都大学, 医学研究科, 准教授 (60314184)
松田 和郎  獨協医科大学, 医学部, 准教授 (80444446)
本間 智  金沢医科大学, 医学部, 教授 (40285581)
木南 利栄子  金沢医科大学, 医学部, 助教 (60163672)
安高 悟  金沢医科大学, 医学部, 助教 (30139787)
Project Period (FY) 2014-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2015: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2014: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Keywords味覚回路 / ブレインマシンインターフェイス / コモン・マーモセット / Juxtacellular Recording法 / 味覚 / BMI / juxtacellular recording法 / juxtacellular Recording法 / ブレイン・マシン-インターフェース / 三次元再構築 / 中枢神経系 / Juxtacellular recording法
Outline of Final Research Achievements

The progress in brain-machine interface in recent years is remarkable. For example, the artificial arms which move freely as thought in the brain, and the artificial cochleas which recover deafness persons have been developed. However, the trial of the gustatory BMI to those who have lost the taste is not yet performed. Although the main functions of oral cavity are ingestion of nutrition, it is very important for improvement in QOL that people taste foods through the mouth deliciously and safely until the last day of the life. So, in the present research, we tried to provide the fundamental informations for development of the gustatory BMI using the newly developed Juxtacellular Recording method in common marmoset brain.

Report

(4 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • Research Products

    (9 results)

All 2017 2016 2015 2014

All Journal Article (4 results) (of which Peer Reviewed: 4 results,  Open Access: 4 results,  Acknowledgement Compliant: 3 results) Presentation (4 results) (of which Invited: 3 results) Patent(Industrial Property Rights) (1 results)

  • [Journal Article] The effect of repeated stress on KCC2 and NKCC1 immunoreactivity in the hippocampus of female mice2016

    • Author(s)
      Tsukahara T, Masuhara M, Iwai H, Sonomura T and Sato T.
    • Journal Title

      Data in Brief.

      Volume: 6 Pages: 521-525

    • DOI

      10.1016/j.dib.2015.12.041

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Three-dimensional structure of seminiferous tubules in the adult mouse.2015

    • Author(s)
      4.Nakata H, Wakayama T, Sonomura T, Honma S, Hatta T, Iseki S.
    • Journal Title

      J Anat.

      Volume: 227 Issue: 5 Pages: 686-694

    • DOI

      10.1111/joa.12375

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Repeated stress-induced expression pattern alterations of the hippocampal chloride transporters KCC2 and NKCC1 associated with behavioral abnormalities in female mice2015

    • Author(s)
      Tsukahara T, Masuhara M, Iwai H, Sonomura T and Sato T.
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 465 Issue: 1 Pages: 145-151

    • DOI

      10.1016/j.bbrc.2015.07.153

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Ascending parabrachio-thalamo-striatal pathways: Potential circuits for integration of gustatory and oral motor functions.2015

    • Author(s)
      Iwai H, Kuramoto E, Yamanaka A, Sonomura T, Uemura M, Goto T.
    • Journal Title

      Neuroscience

      Volume: 294 Pages: 1-13

    • DOI

      10.1016/j.neuroscience.2015.02.045

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Presentation] ヒト海馬に特異的に見られる分節構造の三次元的解析2017

    • Author(s)
      羽藤沙恵、丸山香李、野田博志、薗村貴弘、木南利栄子、安高悟、本間智
    • Organizer
      第122回日本解剖学会総会・全国学術集会
    • Place of Presentation
      長崎大学坂本キャンパス(長崎県長崎市)
    • Related Report
      2016 Annual Research Report
  • [Presentation] 中枢神経系における共焦点レーザー顕微鏡とFIB-SEMを用いた3D-CLEM2015

    • Author(s)
      薗村貴弘
    • Organizer
      第57回歯科基礎医学会学術大会サテライトシンポジウム
    • Place of Presentation
      朱鷺メッセ(新潟県新潟市)
    • Year and Date
      2015-09-11
    • Related Report
      2015 Research-status Report
    • Invited
  • [Presentation] 免疫染色下での共焦点レーザー顕微鏡とFIB-SEMを用いた相関観察の試み2014

    • Author(s)
      薗村貴弘,古田貴寛,中谷郁子,山本洋,本間智,金子武嗣
    • Organizer
      日本顕微鏡学会 第58回シンポジウム
    • Place of Presentation
      九州大学医学部百年講堂(福岡県福岡市)
    • Year and Date
      2014-11-17
    • Related Report
      2014 Research-status Report
    • Invited
  • [Presentation] 中枢神経組織におけるFIB-SEMと共焦点レーザー顕微鏡のCorrelative3次元再構築法2014

    • Author(s)
      薗村貴弘,古田貴寛,中谷郁子,山本洋,本間智,金子武嗣
    • Organizer
      第56回歯科基礎医学会学術大会サテライトシンポジウム
    • Place of Presentation
      福岡国際会議場(福岡県福岡市)
    • Year and Date
      2014-09-25
    • Related Report
      2014 Research-status Report
    • Invited
  • [Patent(Industrial Property Rights)] ブレードホルダー、試料ホルダー及びトリミング方法2017

    • Inventor(s)
      薗村貴弘
    • Industrial Property Rights Holder
      薗村貴弘
    • Industrial Property Rights Type
      特許
    • Filing Date
      2017-03-31
    • Related Report
      2016 Annual Research Report

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Published: 2014-04-04   Modified: 2018-03-22  

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