Empirical study on pulmonary rehabilitation using phasic electrical stimulation during expiration of COPD patients

• Project/Area Number: 26350627
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Rehabilitation science/Welfare engineering
• Research Institution: Osaka Prefecture University
• Principal Investigator: Ito Kenichi 大阪府立大学, 総合リハビリテーション学研究科, 研究員 (30342223)
• Co-Investigator(Kenkyū-buntansha): 野中 紘士 京都橘大学, 健康科学部, 助教C (00565327) ; 堀江 淳 京都橘大学, 健康科学部, 教授 (60461597) ; 川村 博文 甲南女子大学, 看護リハビリテーション学部, 教授 (20326432)
• Project Period (FY): 2014-04-01 – 2018-03-31
• Project Status: Completed (Fiscal Year 2017)
• Budget Amount: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000); Fiscal Year 2016: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000); Fiscal Year 2015: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000); Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
• Keywords: COPD / リハビリテーション / 呼息時電気刺激 / 刺激部位 / 動的肺過膨張 / 慢性呼吸器疾患 / 歩行 / 呼気延長 / 電気刺激 / 最大換気量 / スパイロメトリ / マウスピース / マスク / 妥当性 / 再現性 / 最大吸気量 / 換気効率 / 機序

Outline of Final Research Achievements

To date, we have reported that phasic electrical stimulation during expiration (PESE) in the rehabilitation of patients with chronic obstructive pulmonary disease (COPD) improves ventilation efficiency. In this study, our aim was to elucidate the mechanism of action of PESE for its clinical application, and to identify the optimum site for stimulation. In addition, we examined the effect of dynamic hyperinflation, which is a cause of shortness of breath. From the results of this study, it became evident that the mechanism by which ventilation efficiency improves is the effect of awareness due to PESE. Moreover, the potential of the forearm to be readily exposed makes it a good site for stimulation. On the other hand, we found that PESE does not improve inspiratory capacity, which is an index of dynamic hyperinflation.

Research Products

• [Journal Article] Surface electromyography activity of the rectus abdominis, internal oblique, and external oblique muscles during forced expiration in healthy adults (2016)
  • Author(s): Kenichi Ito
  • Journal Title: Journal of Electromyography and Kinesiology Volume: 28 Pages: 76-81
  • Peer Reviewed / Open Access
• [Journal Article] Electrically stimulated ventilation feedback improves the ventilation pattern in patients with COPD (2015)
  • Author(s): KENICHI ITO etc
  • Journal Title: Journal of Physical Therapy Science Volume: 27 Pages: 325-330
  • NAID: 130004835154
  • Peer Reviewed / Open Access
• [Presentation] Assessment of the mechanism underlying the improvement in ventilation efficiency induced by phasic electrical stimulation during expiration in patients with chronic obstructive pulmonary disease. (2017)
  • Author(s): Ito,K.
  • Organizer: European Respiratory Society Annual Congress 2017 (Milan)
  • Int'l Joint Research
• [Presentation] COPD患者の換気効率を改善する呼息時電気刺激はどこを刺激すべきか (2017)
  • Author(s): 伊藤健一
  • Organizer: 第27回呼吸ケア・リハビリテーション学会学術集会（仙台）
• [Presentation] Validity and Intra-class Reliability of Spirometry Using a Mask Instead of a Mouthpiece (2016)
  • Author(s): Kenichi Ito
  • Organizer: European Respiratory Society Annual Congress 2016
  • Place of Presentation: London
  • Year and Date: 2016-09-03
  • Int'l Joint Research
• [Presentation] Electromyography Activity of the Rectus Abdominis, Internal Oblique, and External Oblique Muscles During Forced Expiration in Healthy Adults (2015)
  • Author(s): Kenichi Ito, Koji Nonaka, Shinya Ogaya, Jun Horie
  • Organizer: European Respiratory Society Annual Congress 2015
  • Place of Presentation: Amsterdam RAI, Amsterdam, Netherlands
  • Year and Date: 2015-09-27
  • Int'l Joint Research