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Development of deep thermal therapy system for joints using noninvasive measurement of temperature distributions by MR thermometry

Research Project

Project/Area Number 26350633
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Rehabilitation science/Welfare engineering
Research InstitutionNippon Medical School

Principal Investigator

Takahashi Kenji  日本医科大学, 医学部, 准教授 (30347447)

Co-Investigator(Kenkyū-buntansha) 黒田 輝  東海大学, 情報理工学部, 教授 (70205243)
加藤 和夫  明治大学, 理工学部, 専任教授 (80115104)
Project Period (FY) 2014-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywords温熱療法 / 関節 / 超音波 / MRI / 温度測定 / 軟骨 / 物理療法
Outline of Final Research Achievements

Feasibility of MR thermometry of the joints using thermal shift of the water proton resonance frequency was confirmed in an animal model. However, reproducibility in human body was poor. Then, Non-Invasive measurement of temperature distributions during hyperthermia treatments using ultrasound B-mode images was investigated. Feasibility of this method was confirmed inside the agar phantom and animal joints. Microwave diathermy utilized in daily medical practice was able to heat the area about 2.5cm from the skin and this diathermy could not increase the temperature of deep area. The heating method using a resonant cavity applicator was developed to heat the deep tissues inside the joints.

Report

(4 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • Research Products

    (13 results)

All 2016 2015 2014

All Journal Article (1 results) (of which Peer Reviewed: 1 results) Presentation (11 results) (of which Int'l Joint Research: 1 results) Book (1 results)

  • [Journal Article] Non-Invasive Measurement of Temperature Distributions During Hyperthermia treatments using Ultrasound B-mode Images2016

    • Author(s)
      Y.Iseki, D. Anan, T. Saito, Y. Shindo, F. Ikuta, K. Takahashi, K.Kato
    • Journal Title

      Thermal Medicine

      Volume: 32 Pages: 17-30

    • NAID

      130005292430

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Presentation] スピン-格子緩和時間による膝関節軟骨の絶対温度分布非侵襲画像化の 可能性2016

    • Author(s)
      木村智也
    • Organizer
      第44回日本磁気共鳴医学会大会
    • Place of Presentation
      さいたま市
    • Year and Date
      2016-09-09
    • Related Report
      2016 Annual Research Report
  • [Presentation] 超音波画像処理によるハイパーサーミア時における温度分布計測2016

    • Author(s)
      阿南大介
    • Organizer
      日本ハイパーサーミア学会第33大会
    • Place of Presentation
      つくば市
    • Year and Date
      2016-09-02
    • Related Report
      2016 Annual Research Report
  • [Presentation] 変形性膝関節症の深部温熱リハビリテーションを目的とした小型空胴共振器加温システムの開発2016

    • Author(s)
      新藤康弘
    • Organizer
      日本ハイパーサーミア学会第33大会
    • Place of Presentation
      つくば市
    • Year and Date
      2016-09-02
    • Related Report
      2016 Annual Research Report
  • [Presentation] スピンー格子緩和時間による膝関節軟骨の絶対温度分布非侵襲画像化の可能性2016

    • Author(s)
      木村智也
    • Organizer
      日本ハイパーサーミア学会第33大会
    • Place of Presentation
      つくば市
    • Year and Date
      2016-09-02
    • Related Report
      2016 Annual Research Report
  • [Presentation] Feasibility of absolute MR thermometry for knee joint cartilage using spin-lattice relaxation time.2016

    • Author(s)
      Kimura K
    • Organizer
      12th International Congress on Hyperthermic Oncology
    • Place of Presentation
      New Orleans
    • Year and Date
      2016-04-11
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 小型空胴共振器を用いた膝関節部の温度分布測定2015

    • Author(s)
      松下拓磨、新藤康弘、加藤和夫、高橋謙治、黒崎弘正
    • Organizer
      第32回日本ハイパーサーミア学会
    • Place of Presentation
      KKRホテル大阪
    • Year and Date
      2015-09-05
    • Related Report
      2015 Research-status Report
  • [Presentation] 変形性関節症の温熱療法のための磁気共鳴による軟骨温度分布の画像化2015

    • Author(s)
      椎名淳史、高橋謙治、加藤和夫
    • Organizer
      第32回日本ハイパーサーミア学会
    • Place of Presentation
      KKRホテル大阪
    • Year and Date
      2015-09-05
    • Related Report
      2015 Research-status Report
  • [Presentation] 変形性膝関節症の温熱治療を目的とした空胴共振器加温システムの加温特性2015

    • Author(s)
      新藤康弘、加藤和夫、高橋謙治、黒崎弘正
    • Organizer
      第32回日本ハイパーサーミア学会
    • Place of Presentation
      KKRホテル大阪
    • Year and Date
      2015-09-04
    • Related Report
      2015 Research-status Report
  • [Presentation] Thermal therapy with a resonant cavity applicator for osteoarthritis.2015

    • Author(s)
      Sato A, Takahashi K, Shindo Y, Kato K, Nakamura H, Takai S
    • Organizer
      61st Annual meeting of the Orthopaedic Research Society
    • Place of Presentation
      ラスベガス、米国
    • Year and Date
      2015-03-28 – 2015-03-31
    • Related Report
      2014 Research-status Report
  • [Presentation] Heating properties of resonant cavity applicator for treatment of osteoarthritis.2014

    • Author(s)
      Matsushita T, Shindo Y, Kato K, Kurosaki H, Takahashi K
    • Organizer
      The 6th Asian congress of hyperthermic oncology & The 31st Japanese congress of thermal medicine
    • Place of Presentation
      福井市
    • Year and Date
      2014-09-05 – 2014-09-06
    • Related Report
      2014 Research-status Report
  • [Presentation] Feasibility of noninvasive magnetic resonance thermometry of the knee joint under thermal therapy.2014

    • Author(s)
      Shiina A, Takahashi K, Nakano J, Kuroda K
    • Organizer
      The 6th Asian congress of hyperthermic oncology & The 31st Japanese congress of thermal medicine
    • Place of Presentation
      福井市
    • Year and Date
      2014-09-05 – 2014-09-06
    • Related Report
      2014 Research-status Report
  • [Book] 変形性関節症の診断と治療2015

    • Author(s)
      高橋謙治、新藤康弘、加藤和夫
    • Total Pages
      222
    • Publisher
      南江堂
    • Related Report
      2014 Research-status Report

URL: 

Published: 2014-04-04   Modified: 2018-03-22  

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