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Neural mechanism of the effect of neurorehabilitation for pain

Research Project

Project/Area Number 26350643
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Rehabilitation science/Welfare engineering
Research InstitutionKio University

Principal Investigator

Morioka Shu  畿央大学, 健康科学部, 教授 (20388903)

Project Period (FY) 2014-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2016: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2015: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywords疼痛 / 疼痛緩和 / EEG / ニューロリハビリテーション / 運動錯覚 / 振動刺激 / 神経メカニズム / 急性痛 / 脳活動 / 視線認知 / 運動観察 / 運動イメージ / 脳波 / LORETA解析 / 脳イメージング
Outline of Final Research Achievements

We showed that illusory kinesthesia by vibratory tendon stimulation as neurorehabilitation for a distal radius fracture reduces pain (Imai 2016). The purpose of this study was to examine the activate motor cortex of patients suffering from pain during illusory kinesthesia by vibratory tendon stimulation using EEG, and we investigated the relevance of motor cortex and post-operated pain to clarify analgesia mechanism. As a results, we showed it became clear that the activity of the bilateral sensorimotor area (C3, C4) was provided when I brought about an illusory kinesthesia by the tendon vibration stimulation after surgery of distal radius fracture next day with. In addition, we revealed that pain at rest and movement at pain was improved after intervention. A negative correlation was seen in the C3 and C4ch ERD value and the amount of change in pain at rest. These results suggest that sensorimotor areas activated by the illusory kinesthesia may be involved in pain relief.

Report

(4 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • Research Products

    (42 results)

All 2017 2016 2015 2014 Other

All Journal Article (21 results) (of which Int'l Joint Research: 11 results,  Peer Reviewed: 20 results,  Open Access: 16 results,  Acknowledgement Compliant: 2 results) Presentation (17 results) (of which Int'l Joint Research: 12 results,  Invited: 5 results) Book (3 results) Remarks (1 results)

  • [Journal Article] Effect of illusory kinesthesia on hand function in patients with distal radius fractures: A quasi-randomized controlled study.2017

    • Author(s)
      Imai R, Osumi M, Ishigaki T, Morioka S
    • Journal Title

      Clinical Rehabilitation

      Volume: 31 Issue: 5 Pages: 696-701

    • DOI

      10.1177/0269215516688048

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Optimal control of reaching is disturbed in complex regional pain syndrome: a single-case study.2017

    • Author(s)
      Osumi M, Sumitani M, Kumagaya SI, Morioka S.
    • Journal Title

      Journal of Pain Research

      Volume: 10 Pages: 167-173

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Effects of wheelchair propulsion on neuropathic pain and resting electroencephalography after spinal cord injury.2017

    • Author(s)
      Sato G, Osumi M, Morioka S
    • Journal Title

      Journal of Rehabilitation Medicine

      Volume: 31 Issue: 2 Pages: 136-143

    • DOI

      10.2340/16501977-2185

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Dysesthesia symptoms produced by sensorimotor incongruence in healthy volunteers: an electroencephalogram study.2016

    • Author(s)
      Katayama O, Osumi M, Kodama T, Morioka S
    • Journal Title

      Journal of Pain Research

      Volume: 9 Pages: 1197-1204

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Restoring movement representation and alleviating phantom limb pain through short-term neurorehabilitation with a virtual reality system.2016

    • Author(s)
      M. Osumi, A. Ichinose, M. Sumitani, N. Wake, Y. Sano, A. Yozu, S. Kumagaya,Y. Kuniyoshi, S. Morioka
    • Journal Title

      European Journal of Pain

      Volume: 21 Issue: 1 Pages: 140-147

    • DOI

      10.1002/ejp.910

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Incongruence between Verbal and Non-Verbal Information Enhances the Late Positive Potential.2016

    • Author(s)
      Morioka S, Osumi M, Shiotani M, Nobusako S, Maeoka H, Okada Y, Hiyamizu M, Matsuo A
    • Journal Title

      PLoS One

      Volume: 11 Issue: 10 Pages: e0164633-e0164633

    • DOI

      10.1371/journal.pone.0164633

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] 疼痛の神経心理学 -身体性と社会性の観点から-2016

    • Author(s)
      森岡周
    • Journal Title

      神経心理学

      Volume: 32 Pages: 208-215

    • NAID

      130005268787

    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Journal Article] Structured movement representations of a phantom limb associated with phantom limb pain.2015

    • Author(s)
      Osumi M, Sumitani M, Wake N, Sano Y, Ichinose A, Kumagaya SI, Kuniyoshi Y, Morioka S.
    • Journal Title

      Neurosci Lett

      Volume: 605 Pages: 7-11

    • DOI

      10.1016/j.neulet.2015.08.009

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] The influence of repeated pain stimulation on the emotional aspect of pain: a preliminary study in healthy volunteers.2015

    • Author(s)
      Maeoka H, Hiyamizu M, Matsuo A, Morioka S.
    • Journal Title

      J Pain Res

      Volume: 8 Pages: 431-436

    • DOI

      10.2147/jpr.s86732

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] The effect of virtual visual feedback on supernumerary phantom limb pain in a patient with high cervical cord injury: a single-case design study.2015

    • Author(s)
      Katayama O, Iki H, Sawa S, Osumi M, Morioka S.
    • Journal Title

      Neurocase

      Volume: 21 Pages: 786-792

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Effects of Facial Expression and Language on Trustworthiness and Brain Activities.2015

    • Author(s)
      Morioka S, Osumi M, Okamoto M, Matsuo A.
    • Journal Title

      Int J Brain Res

      Volume: 2015 Pages: 719213-719213

    • DOI

      10.1155/2015/719213

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] 脊髄損傷後の疼痛と破局的思考ならびに疼痛への態度との関係.2015

    • Author(s)
      佐藤剛介,田中陽一,大住倫弘,森岡 周
    • Journal Title

      日本運動器疼痛学会誌

      Volume: 7 Pages: 159-166

    • Related Report
      2015 Research-status Report
    • Peer Reviewed
  • [Journal Article] ビデオを用いた患者教育による術後痛および破局的思考の改善効果.2015

    • Author(s)
      平川善之,原 道也,藤原 明,花田弘文,問田純一,平賀勇貴,森岡 周.
    • Journal Title

      Pain Research

      Volume: 30 Pages: 158-166

    • NAID

      130005093933

    • Related Report
      2015 Research-status Report
    • Peer Reviewed
  • [Journal Article] 橈骨遠位端骨折術後患者に対する腱振動刺激に運動錯覚が急性疼痛に与える影響-手術翌日からの早期介入-2015

    • Author(s)
      今井亮太,大住倫弘,平川善之,中野英樹,福本貴彦,森岡 周.
    • Journal Title

      理学療法学

      Volume: 42 Pages: 1-7

    • Related Report
      2015 Research-status Report
    • Peer Reviewed
  • [Journal Article] he effect of virtual visual feedback on supernumerary phantom limb pain in a patient with high cervical cord injury: a single-case design study2015

    • Author(s)
      Katayama O, Iki H, Sawa S, Osumi M, Morioka S
    • Journal Title

      Neurocase

      Volume: Epub ahead of print Pages: 1-7

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] actors associated with the modulation of pain by visual distortion of body size2014

    • Author(s)
      Osumi M, Imai R, Ueta K, Nakano H, Nobusako S, Morioka S
    • Journal Title

      Front Hum Neurosci

      Volume: 8 Pages: 00137-00137

    • DOI

      10.3389/fnhum.2014.00137

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Activation of the serotonergic system by pedaling exercise changes anterior cingulate cortex activity and improves negative emotion2014

    • Author(s)
      Ohmatsu S, Nakano H, Tominaga T, Terakawa Y, Murata T, Morioka S
    • Journal Title

      Behav Brain Res

      Volume: 270 Pages: 112-117

    • DOI

      10.1016/j.bbr.2014.04.017

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] The relationship among psychological factors, neglect-like symptoms and postoperative pain after total knee arthroplasty2014

    • Author(s)
      Hirakawa Y, Hara M, Fujiwara A, Hanada H, Morioka S
    • Journal Title

      Pain Res Manag

      Volume: 19 Pages: 251-256

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Negative body image associated with changes in the visual body appearance increases pain perception2014

    • Author(s)
      Osumi M, Imai R, Ueta K, Nobusako S, Morioka S.
    • Journal Title

      PLoS One

      Volume: 9 Issue: 9 Pages: e107376-e107376

    • DOI

      10.1371/journal.pone.0107376

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Tactile localization training for pain, sensory disturbance, and distorted body image: a case study of complex regional pain syndrome2014

    • Author(s)
      Osumi M, Okuno H, Nishigami T, Ueta K, Morioka S
    • Journal Title

      Neurocase

      Volume: Epub ahead of print Pages: 1-7

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Brain Activity Associated with the Illusion of Motion Evoked by Different Vibration Stimulation Devices: An fNIRS Study2014

    • Author(s)
      Imai R, Hayashida K, Nakano H, Morioka S
    • Journal Title

      Journal of Physical Therapy Science

      Volume: 26 Issue: 7 Pages: 1115-1119

    • DOI

      10.1589/jpts.26.1115

    • NAID

      130004677698

    • ISSN
      0915-5287, 2187-5626
    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Presentation] Effects of illusory kinesthesia by vibratory tendon stimulation on acute pain2017

    • Author(s)
      Morioka S
    • Organizer
      PCS International Conference of Neuroscience
    • Place of Presentation
      リスボン
    • Year and Date
      2017-04-07
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Effects of relationship and gender difference on pain2016

    • Author(s)
      Maeoka H, Matsuo A, Hiyamizu M, Morioka S
    • Organizer
      Society for Neuroscience 2016
    • Place of Presentation
      サンディエゴ
    • Year and Date
      2016-11-13
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] The personality traits contribute to voluntary pain-related avoidance behavior2016

    • Author(s)
      Nishi Y, Osumi M, Nobusako S, Morioka S
    • Organizer
      Society for Neuroscience 2016
    • Place of Presentation
      サンディエゴ
    • Year and Date
      2016-11-13
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Neural network of dysesthesia symptoms produced by sensorimotor incongruence in healthy volunteers. A functional connectivity analysis2016

    • Author(s)
      Katayama O, Osumi M, Imai1 R, Kodama T, Morioka S
    • Organizer
      Society for Neuroscience 2016
    • Place of Presentation
      サンディエゴ
    • Year and Date
      2016-11-13
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Restoring movement representation through neurorehabilitation with a virtual reality system alleviate phantom limb pain2016

    • Author(s)
      Osumi M, Ichinose A, Sumitani M, Wake N, Sano Y, Yozu A, Kumagaya S, Kuniyoshi Y, Morioka S
    • Organizer
      16th World Congress on Pain.
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2016-09-26
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Influence of transcranial direct current stimulation of the right dorsolateral prefrontal cortex on repeated pain stimulation2016

    • Author(s)
      Maeoka H, Hiyamizu M, Matsuo A, Morioka S
    • Organizer
      16th World Congress on Pain.
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2016-09-26
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] The relationship between interoceptive sensitivity and sympathetic variability during pain stimulation2016

    • Author(s)
      Nishi Y, Osumi M, Morioka S
    • Organizer
      16th World Congress on Pain
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2016-09-26
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] The relationship between personality traits and pain-related avoidance learning using voluntary movement paradigm2016

    • Author(s)
      Nishi Y, Osumi M, Nobusako S, Morioka S
    • Organizer
      16th World Congress on Pain
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2016-09-26
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Uncovering the influence of social skills and other psychosociological factors on pain sensitivity using structural equation modeling2016

    • Author(s)
      Tanaka Y, Osumi M, Morioka S
    • Organizer
      16th World Congress on Pain
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2016-09-26
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Pain relief and descending pain inhibitory system in N-back task: a study using electroencephalography and urinary serotonin measurements2016

    • Author(s)
      Yasuda N, Ishigaki T, Nisii Y, Morioka S
    • Organizer
      16th World Congress on Pain
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2016-09-26
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Neural network of dysesthesia produced by sensorimotor incongruence. A functional connectivity analysis2016

    • Author(s)
      Katayama O, Osumi M, Imai1 R, Kodama T, Morioka S
    • Organizer
      16th World Congress on Pain
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2016-09-26
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Influence of illusory kinesthesia by vibratory tendon stimulation on Activities of Daily Living (ADL) after surgery disatl radius fractures2016

    • Author(s)
      Imai R, Osumi M, Morioka S
    • Organizer
      16th World Congress on Pain
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2016-09-26
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] ニューロリハビリテーション -その原則、手段、そして未来-2014

    • Author(s)
      森岡周
    • Organizer
      第32回東北理学療法学術大会
    • Place of Presentation
      山形テルサ
    • Year and Date
      2014-11-29 – 2014-11-30
    • Related Report
      2014 Research-status Report
    • Invited
  • [Presentation] ニューロリハビリテーションの概念とその戦略2014

    • Author(s)
      森岡周
    • Organizer
      九州理学療法士・作業療法士合同学会2014
    • Place of Presentation
      佐賀市文化会館
    • Year and Date
      2014-11-22 – 2014-11-23
    • Related Report
      2014 Research-status Report
    • Invited
  • [Presentation] Effects of inconsistency between facial and verbal expressions on degree of trust and brain activity.2014

    • Author(s)
      Morioka S, Okamoto M, Osumi M, Matsuo A
    • Organizer
      44th Annual Meeting of Society for Neuroscience
    • Place of Presentation
      ワシントンDCコンベンションセンター
    • Year and Date
      2014-11-15 – 2014-11-19
    • Related Report
      2014 Research-status Report
  • [Presentation] 疼痛に対するペインリハビリテーションの確立に向けて2014

    • Author(s)
      森岡周
    • Organizer
      第19回日本ペインリハビリテーション学会
    • Place of Presentation
      大阪産業創造館
    • Year and Date
      2014-09-06 – 2014-09-07
    • Related Report
      2014 Research-status Report
    • Invited
  • [Presentation] 臨床とエビデンスとの対話2014

    • Author(s)
      森岡周
    • Organizer
      第20回岡山県理学療法士学会
    • Place of Presentation
      岡山ロイヤルホテル
    • Year and Date
      2014-06-22
    • Related Report
      2014 Research-status Report
    • Invited
  • [Book] リハビリテーションのための脳・神経科学入門(第2版)2016

    • Author(s)
      森岡周
    • Total Pages
      234
    • Publisher
      協同医書出版社
    • Related Report
      2016 Annual Research Report
  • [Book] 臨床思考を踏まえる理学療法プラクティス /感覚入力で挑む2015

    • Author(s)
      大住倫弘,森岡 周
    • Total Pages
      264
    • Publisher
      文光堂
    • Related Report
      2015 Research-status Report
  • [Book] 脳を学ぶ-「ひと」とその社会がわかる生物学2014

    • Author(s)
      森岡周
    • Total Pages
      128
    • Publisher
      協同医書出版社
    • Related Report
      2014 Research-status Report
  • [Remarks] 畿央大学ニューロリハビリテーション研究センター

    • URL

      http://www.kio.ac.jp/nrc/

    • Related Report
      2016 Annual Research Report 2015 Research-status Report

URL: 

Published: 2014-04-04   Modified: 2018-03-22  

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