| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Outline of Final Research Achievements |
A basic study of activation of cerebral endothelial progenitor cells by physical training were studied in a mouse brain ischemia model. The results were as follows. In acute cerebral ischemia group, the capillary density of ischemic cerebral hemisphere increased by 1.9 times in a week, and increased by 2.7 times in two weeks from the beginning of physical training, compared with control. In chronic cerebral ischemia group, the capillary density of ischemic cerebral hemisphere increased by 2.0 times in two weeks, compared with control. We suppose neovascularization in the cerebral ischemic hemisphere would be accelerated by physical training, and associated with activation of cerebral endothelial progenitor cells.
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