Effcts of voluntary exercise on neurotransmitters in the preoptic area and anterior hypothalamus and thermoregulation in rats
| Project/Area Number |
26350822
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Sports science
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| Research Institution | Rikkyo University |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
HASEGAWA Hiroshi 広島大学, 総合科学研究科, 教授 (70314713)
YANAGITA Shinya 東京理科大学, 理工学部, 助教 (80461755)
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| Research Collaborator |
SUZUKI Kota
MATSUMURA Takeru
NAKAGAWA Hikaru
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| Project Period (FY) |
2014-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2015: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2014: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
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| Keywords | 脳内神経伝達物質 / 自発運動 / 体温調節 / 深部体温 / 心拍数 / 活動量 / 神経伝達物質 |
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| Outline of Final Research Achievements |
The preoptic area and anterior hypothalamus (PO/AH) is considered to be the primary locus for thermoregulatory system. In addition, serotonin (5-HT), dopamine (DA) and norepinephrine (NE) are very important monoaminergic neurotransmitter and its system has been involved in the regulation of thermoregulation. In this study, we investigated in the effects of voluntary exercise on brain monoaminergic neurotransmitters and thermoregulation in rats. Results showed that the heart rate in the voluntary exercise group were lower level compared with control group. Furthermore, core body temperature in the exercise group also showed clear circadian rhythm during the day compared with control group. The levels of NE and DA in the PO/AH in voluntary exercise group were higher than control group significantly. These results indicate that voluntary exercise may affect on the health and condition in the brain neurotransmitters.
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Report
(5 results)
Research Products
(12 results)
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[Journal Article] The Prevalence and Clinicopathological Characteristics of High-Grade Pancreatic Intraepithelial Neoplasia: Autopsy Study Evaluating the Entire Pancreatic Parenchyma.2017
Author(s)
1.Matsuda Y, Furukawa T, Yachida S, Nishimura M, Seki A, Nonaka K, Aida J, Takubo K, Ishiwata T, Kimura W, Arai T, Mino-Kenudson M.
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Journal Title
Ｐａｎｃｒｅａｓ
Volume: 46
Issue: 5
Pages: 658-664
DOI
Related Report
Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
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