• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Relationship between brain migration and anti-anxiety-like effect in inhalation administration of essential oil

Research Project

Project/Area Number 26350873
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Applied health science
Research InstitutionToho University

Principal Investigator

SATOU Tadaaki  東邦大学, 薬学部, 准教授 (80287549)

Project Period (FY) 2014-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2014: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywords植物精油 / 脳内移行性 / 吸入投与 / 情動 / 炎症 / ストレス / 揮発成分 / 抗不安作用 / 鎮静作用 / 脳内移行
Outline of Final Research Achievements

Patients with psychiatric disorders with disabilities in the heart and brain have increased in recent years. Therefore, if people can effectively utilize aromatic plant therapy using plant essential oil at the stage of pre-illness, we think that it is sufficiently possible to reduce the number of patients with mental illness. However, recently, since the use standards of aromatic plant therapy are not clear, many cases have been reported that deteriorate physical condition due to excessive scent. It is necessary to prepare scientific usage standards for urgent aromatic plant therapy. In this study, research was conducted with the objective of acquiring scientific basic data for using criteria for aromatic plant therapy. As a result, it was revealed that by inhaling plant essential oil, volatile components easily migrated into the brain, thereby affecting emotion.

Report

(4 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • Research Products

    (8 results)

All 2017 2016 2015

All Journal Article (5 results) (of which Peer Reviewed: 5 results,  Acknowledgement Compliant: 5 results) Presentation (3 results) (of which Int'l Joint Research: 2 results)

  • [Journal Article] Mouse brain concentrations of α-pinene, limonene, linalool, and 1,8-cineole following inhalation.2017

    • Author(s)
      Satou T., Hayakawa M., Kasuya H., Masuo Y., Koike K.
    • Journal Title

      Flavour and Fragrance Journal

      Volume: 32(2) Issue: 1 Pages: 36-39

    • DOI

      10.1002/ffj.3342

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Anti-fatigue activity of essential oil from thyme (linalool chemotype) in the polyriboinosinic: polyribocytidylic acid-induced brain fatigue mouse.2016

    • Author(s)
      Hayakawa M., Satou T., Masuo Y., Koike K.
    • Journal Title

      Flavour and Fragrance Journal

      Volume: 31(5) Issue: 5 Pages: 395-399

    • DOI

      10.1002/ffj.3328

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Intracerebral Distribution of α-Pinene and the Anxiolytic-like Effect in Mice Following Inhaled Administration of Essential Oil from Chamaecyparis obtusa2015

    • Author(s)
      Hikaru Kasuya, Sayuka Iida, Kurumi Ono, Tadaaki Satou, Kazuo Koike
    • Journal Title

      Natural Product Communications

      Volume: 10 (8) Pages: 1479-1482

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Relationship Between Emotional Behavior in Mice and the Concentration of (+)-α-Santalol in the Brain2015

    • Author(s)
      Tadaaki Satou, Yuko Ogawa, Kazuo Koike
    • Journal Title

      Phytotherapy Research

      Volume: 29 (8) Issue: 8 Pages: 1246-1250

    • DOI

      10.1002/ptr.5372

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Relationship between emotional behavior in mice and the concentration of (+)-α-santalol in the brain.2015

    • Author(s)
      Tadaaki Satou, Yuko Ogawa, Kazuo Koike.
    • Journal Title

      Phytotherapy Research

      Volume: 29

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Presentation] Intracerebral distribution of α-pinene and the anxiolytic-like effect in mice following inhaled administration of essential oil from Chamaecyparis obtusa2015

    • Author(s)
      Tadaaki Satou, Hikaru Kasuya, Sayuka Iida, Kurumi Ono, Kazuo Koike
    • Organizer
      9th Joint Seminar on Biomedical Sciences 2015
    • Place of Presentation
      Chiang Mai(Thailand)
    • Year and Date
      2015-11-04
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] Relationship Between Emotional Behavior in Mice and the Concentration of (+)-α-Santalol in the Brain2015

    • Author(s)
      Tadaaki Satou, Yuko Ogawa, Kazuo Koike
    • Organizer
      Inaugural Symposium Phytochemical Society of Asia (PSA) 2015
    • Place of Presentation
      Tokushima Bunri University (Nishihama, Yamashiro-cho, Tokushima)
    • Year and Date
      2015-08-30
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] (+)-α-Santarolがマウスの情動に及ぼす影響と脳内移行性2015

    • Author(s)
      小川優子,佐藤忠章,小池一男
    • Organizer
      東邦大学4学部合同学術集会
    • Place of Presentation
      東邦大学(千葉県,船橋市)
    • Year and Date
      2015-03-14
    • Related Report
      2014 Research-status Report

URL: 

Published: 2014-04-04   Modified: 2018-03-22  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi