Project/Area Number |
26350876
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Applied health science
|
Research Institution | Prefectural University of Hiroshima |
Principal Investigator |
Iida Tadayuki 県立広島大学, 保健福祉学部(三原キャンパス), 教授 (50290549)
|
Co-Investigator(Kenkyū-buntansha) |
八谷 寛 藤田保健衛生大学, 医学部, 教授 (30324437)
伊藤 康宏 藤田保健衛生大学, 保健学研究科, 教授 (40176368)
井上 顕 高知大学, 教育研究部医療学系臨床医学部門, 教授 (40469036)
巽 あさみ 浜松医科大学, 医学部, 教授 (90298513)
|
Project Period (FY) |
2014-04-01 – 2018-03-31
|
Project Status |
Completed (Fiscal Year 2017)
|
Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2016: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2015: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2014: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
|
Keywords | 睡眠 / 自律神経活動 / ストレス / u-8-OHdG / u-5-HT / SDS / STAI / ストレス関連バイオマーカー / 心理的ストレス / 自律神経 / 感情 |
Outline of Final Research Achievements |
The percentage of people with work- and life-related anxiety, worry, and stress is increasing every year, and it is said to exceed 60%. The relationship between psychological stress and oxidative stress has become a focus of interest, and the mechanism by which psychological stress increases reactive oxygen species (ROS) is slowly being elucidated. This study focused on [Association between the Profile of Mood States and Autonomic Nervous System Activity during Sleep] and [Effects of psychological stress on the urine 8-hydroxy-deoxyguanosine levels in young female students, taking into account the menstrual cycle]. Mood changes showed an association with sympathetic and parasympathetic nervous system activities during sleep, suggesting the possibility of these activities influencing moods.This study also showed that U8-OHdG levels increased with the psychological stress of a national license examination.
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