| Project/Area Number |
26350945
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Childhood science (childhood environment science)
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| Research Institution | Kyoto Women's University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
中山 貴夫 京都女子大学, 現代社会学部, 准教授 (00379158)
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| Co-Investigator(Renkei-kenkyūsha) |
MURAI Toshiya 京都大学, 医学研究科, 教授 (30335286)
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| Project Period (FY) |
2014-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | 児童精神医学 / 統合失調症 / スクリーニング / 予防医学 / 包括的介入モデル / 精神保健 / 環境保健 |
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| Outline of Final Research Achievements |
This study is a retrospective report of childhood neurobehavioral assessment in patients with schizophrenia and healthy controls in their twenties using the CBCL4-18 to elucidate the subclinical characteristics of schizophrenic children and to find out indicators which predict later development of schizophrenia. A logistic regression using the eight CBCL syndrome subscale T-scores adequately classified 85.8％ of the population and suggests that subclinical neurobehavioral characteristics of schizophrenia already exist in the patients' childhood. The Combination Pattern of these subclinical characteristics (Withdrawal, Thought problems and Lack of aggression ) would predict later development of schizophrenia. We have developed the early screening system for the risk of psychosis in childhood using obtained logistic regression model and constructed a comprehensive intervention model incorporating this screening system.
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