| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Outline of Final Research Achievements |
Probiotic bacteria and their bacterial components are known to keep the host homeostasis and modulate the host immune systems by interacting with intestinal immune cells. Previously we found that a traditional Japanese vinegar kurozu contains acetic acid bacterial components including lipoproteins and lipopolysaccharide, which are considered to contribute to host immune system modulation. In this study, we elucidated chemical structure of the lipopolysaccharide and found that the lipopolysaccharide exist as nano-sized vesicles in kurozu.
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