Development of self-aligned nano-carbon biosensors using glycan for the highly pathogenic avian influenza virus
| Project/Area Number |
26390030
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Multi-year Fund |
|---|
| Section | 一般 |
|---|
| Research Field |
Nanomaterials engineering
|
|---|
| Research Institution | Chubu University |
|---|
Principal Investigator |
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
鈴木 康夫 中部大学, 生命健康科学部, 客員教授 (00046278)
|
|---|
| Co-Investigator(Renkei-kenkyūsha) |
MAEHASHI Kenzo 東京農工大学, 大学院・工学研究院, 教授 (40229323)
OKAMOTO Kazumasa 北海道大学, 大学院・工学研究院, 助教 (10437353)
|
|---|
| Project Period (FY) |
2014-04-01 – 2017-03-31
|
| Project Status |
Completed (Fiscal Year 2016)
|
| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2014: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
|
|---|
| Keywords | ナノカーボン応用 / バイオセンサー / ナノカーボン成長制御 / 自己組織化成長 / 電気伝導率制御 / 糖鎖の評価・最適化 / インフルエンザ感染性 |
|---|
| Outline of Final Research Achievements |
We have developed a self-alignment process for nano-carbon field effect transistors (FETs) using a carbon nanowall (CNW). Higher growth temperature enlarges the grain size in CNWs, and this results in a decrease in carrier scattering at the grain boundary. Using the low temperature buffer, we can improve the electric properties of channels. We also discussed about the plasma processes to improve the device properties of CNW-FETs. And we measured the pH dependence of the device properties. The binding molecules are known to be the key components for bio-sensors. We estimated the size of detection molecules of glycan for influenza viruses using atomic force microscopy. The typical molecule size is around 1 nm, and this may be suitable for electronic detection using a FET structure. We have also checked the selectivity of the graphene bio sensor. Furthermore, we have also evaluated the specific binding properties for the wild type of influenza virus in Egypt, Indonesia, and so forth.
|
Report
(4 results)
Research Products
(32 results)
-
-
-
-
-
-
-
-
-
-
-
[Presentation] ヒト感染性の即時鑑別のための糖鎖機能化グラフェンを用いたインフルエンザウイルスの検出2017
Author(s)
川田拓哉, 小野尭生, 金井康, 大野恭秀, 前橋兼三, 井上恒一, 渡邊洋平, 河原敏男, 鈴木康夫, 中北愼一, 松本和彦
Organizer
第64回応用物理学会春季学術講演会
Place of Presentation
パシフィコ横浜 (神奈川県横浜市)
Year and Date
2017-03-15
Related Report
-
-
[Presentation] カーボンナノウォールFETのためのプラズマプロセス2016
Author(s)
河原敏男, Singh R. Kumar, 大野恭秀, 前橋兼三, 松本和彦, 岡本一将, 宇都宮里佐, 松葉晃明
Organizer
第57回真空に関する連合講演会・第36回表面科学学術講演会
Place of Presentation
名古屋国際会議場 (愛知県名古屋市)
Year and Date
2016-11-30
Related Report
-
-
-
-
[Presentation] Developments of the nano-carbon bio sensors using glycan for influenza virus2016
Author(s)
Toshio Kawahara, Hiroaki Hiramatsu, Yasuo Suzuki, Shin-ichi Nakakita, Yasuhide Ohno, Kenzo Maehashi, Kazuhiko Matsumoto, Kazumasa Okamoto, Teruaki Matsuba, Risa Utsunomiya
Organizer
13th International Conference on Atomically Controlled Surfaces, Interfaces and Nanostructures (ACSIN2016)
Place of Presentation
Frascati National Laboratories (Rome, Italy)
Year and Date
2016-10-14
Related Report
Int'l Joint Research
-
[Presentation] 糖鎖機能化グラフェンFET を用いた抗ウイルス薬効評価のためのノイラミニダーゼ反応計測2016
Author(s)
鎌田果歩, 小野尭生, 金井康, 大野恭秀, 前橋兼三, 井上恒一, 渡邊洋平, 河原敏男, 鈴木康夫, 中北愼一, 松本和彦
Organizer
第77回応用物理学会秋季学術講演会
Place of Presentation
朱鷺メッセ (新潟県新潟市)
Year and Date
2016-09-15
Related Report
Invited
-
-
-
-
-
-
-
-
-
[Presentation] Spreading of Influenza Virus in North Africa and Southeast Asia2015
Author(s)
T. Kawahara, Y. Suzuki, A. Tamada, N. Sriwilaijaroen, K. Matsumoto
Organizer
The 5th Asia-Africa Sustainable Energy Forum Jointly with 7th International Workshop on Sahara Solar Breeder
Place of Presentation
30th Anniversary Hall, University of Tsukuba, Tsukuba, Japan （茨城県つくば市）
Year and Date
2015-05-11
Related Report
Int'l Joint Research / Invited
-
[Presentation] 糖鎖修飾グラフェンFETを用いたインフルエンザウイルスセンサの開発2015
Author(s)
麻植丈史, 生田昂, 林亮太, 金井康, 大野恭秀, 前橋兼三, 井上恒一, 松本和彦, 渡邊洋平, 河原敏男, 鈴木康夫, 中北愼一
Organizer
第62回応用物理学会春季学術講演会
Place of Presentation
東海大学湘南キャンパス(神奈川県平塚市)
Year and Date
2015-03-11 – 2015-03-14
Related Report
-
[Presentation] Electrical detection of lectin using glycan-modified graphene field-effect transistors for highly sensitive influenza virus sensor2014
Author(s)
T. Oe, Y. Kanai, Y. Ohno, K. Maehashi, K. Inoue, K. Matsumoto, Y. Watanabe, T. Kawahara, Y. Suzuki, S. Nakakita
Organizer
27th International Microprocesses and Nanotechnology Conference (MNC2014)
Place of Presentation
Hilton Fukuoka Sea Hawk, Fukuoka, Japan (福岡県福岡市)
Year and Date
2014-11-04 – 2014-11-07
Related Report
-
-
-
