| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2015: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2014: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
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| Outline of Final Research Achievements |
DNA binding proteins such as RecA proteins and single-stranded DNA binding (SSB) proteins were reacted with various carbon nanotube (CNT) surfaces that were wrapped with DNA and polymers in order to study bio-recognition functions of the protein molecules and interactions among the molecules. Styles of protein adsorption and binding was significantly changed due to surface conditions of CNTs. Especially, two different interactions were competitive. One is interactions between proteins and DNA, and the other is those between proteins and CNTs. This suggests that interactions of DNA and DNA binding proteins are well controlled. In addition, regulation of the two interactions is probably one of the important factors for developing nanobiodevices using CNTs.
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