Conversion of Dinitrogen to Organo-Nitrogen Compounds by Multimetallic Hydride Complexes
| Project/Area Number |
26410082
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Multi-year Fund |
|---|
| Section | 一般 |
|---|
| Research Field |
Inorganic chemistry
|
|---|
| Research Institution | Institute of Physical and Chemical Research |
|---|
Principal Investigator |
SHIMA Takanori 国立研究開発法人理化学研究所, 侯有機金属化学研究室, 専任研究員 (60391976)
|
|---|
| Project Period (FY) |
2014-04-01 – 2017-03-31
|
| Project Status |
Completed (Fiscal Year 2016)
|
| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2014: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
|
|---|
| Keywords | 窒素分子活性化 / チタンヒドリド錯体 / ニトリド錯体 / ニトリル / 酸塩化物 / 窒素活性化 / 含窒素有機化合物 / チタン錯体 / ヒドリド錯体 |
|---|
| Outline of Final Research Achievements |
At present, ammonia, produced by the Haber-Bosch process, is the only nitrogen source for the industrial preparation of nitrogen-containing organic products. Although the activation and functionalization of N2 under milder conditions have received much recent interest, studies on the direct use of N2 as a feedstock for organic synthesis are still in their infancy.
We have found that the titanium diimide/dinitride complex, formed by activation of N2 with H2 and the titanium trialkyl complex, served as a unique platform for the synthesis of nitriles through reaction with acid chlorides. This protocol features simple reaction condition, no requirement for extra reagents, and unprecedented functional group tolerance. 15N-Isotope labeled nitriles can also be efficiently prepared by using the 15N-enriched diimide/dinitride analogue derived from 15N2 gas. The titanium complexes could be recycled by treatment of the crude reaction mixture with HCl.
|
Report
(4 results)
Research Products
(32 results)
