Synthesis of Nitroaniline Derivatives by a Built-in Method of Unstable Nitromalonaldehyde
| Project/Area Number |
26410123
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Synthetic chemistry
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| Research Institution | Kochi University of Technology |
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Principal Investigator |
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2016: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2015: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2014: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
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| Keywords | 環変換反応 / ニトロピリジン / ニトロアニリン / ビシクロ中間体 / ジニトロピリドン / 酢酸アンモニウム / 三成分系反応 / アルケニルピリジン / アルキニルピリジン / 多成分系反応 |
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| Outline of Final Research Achievements |
Three component ring transformation of dinitropyridone, ketone, and ammonium acetate proceeded to afford nitropyridines and nitroanilines. These products are not easily available by alternative methods. To the contrary, the present method requires only simple experimental manipulations. In addition, modification of the product can be easily perfomed by only changing the ketone. Hence, it is applicable to various purposes.
The synthesized products have both electron-donating and -withdrawing groups, which brings about the biased electron density. Such frameworks are often used for biologically compounds and optical materials. Hence, the present method facilitates the development of new functional materials.
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Report
(4 results)
Research Products
(10 results)
