• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Development of New Methods for the Synthesis of Complex Interlocked Compounds

Research Project

Project/Area Number 26410125
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Synthetic chemistry
Research InstitutionTokyo University of Science

Principal Investigator

SAITO Shinichi  東京理科大学, 理学部第一部化学科, 教授 (80283076)

Project Period (FY) 2014-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywordsインターロック化合物 / ロタキサン / 触媒反応 / 動的挙動 / カップリング反応 / CDスペクトル / 銅触媒 / 大環状化合物
Outline of Final Research Achievements

Interlocked compounds are molecules which consist of two or more components, which were connected by mechanical bonds. In this study we synthesized interlocked compounds composted of three components by applying the synthetic methodologies we recently developed. For example, we synthesized [3]rotaxanes which consist of two axle components and one ring component. Rotacatenanes, which were composed of one axle component and two ring components, were efficiently prepared. We also studied the properties of the interlocked compounds we synthesized.

Report

(4 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • Research Products

    (42 results)

All 2017 2016 2015 2014 Other

All Journal Article (8 results) (of which Peer Reviewed: 7 results,  Open Access: 2 results,  Acknowledgement Compliant: 7 results) Presentation (33 results) (of which Int'l Joint Research: 4 results,  Invited: 1 results) Remarks (1 results)

  • [Journal Article] Synthesis of Interlocked Compounds Utilizing Bond-Forming Reactions Mediated by Macrocyclic Phenanthroline-Cu Complexes2017

    • Author(s)
      Yukari Yamazaki, Yuichiro Mutoh, and Shinichi Saito
    • Journal Title

      Chem. Lett.

      Volume: 印刷中

    • NAID

      130005709506

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Synthesis and the Shuttling Behavior of [2]Rotaxanes with Pyrrole Moiety2016

    • Author(s)
      Matsuoka, Yusuke Mutoh, Yuichiro Azumaya, Isao Kikkawa, Shoko Kasama, Takeshi Saito, Shinichi
    • Journal Title

      JOURNAL OF ORGANIC CHEMISTRY

      Volume: 81 Issue: 9 Pages: 3479-3487

    • DOI

      10.1021/acs.joc.5b02911

    • Related Report
      2015 Research-status Report
    • Open Access / Acknowledgement Compliant
  • [Journal Article] Sequence-Selective Synthesis of Rotacatenane Isomers2016

    • Author(s)
      Ryuto Hayashi, Petr Slavik, Yuichiro Mutoh, Takeshi Kasama, and Shinichi Saito
    • Journal Title

      JOURNAL OF ORGANIC CHEMISTRY

      Volume: 81 Issue: 3 Pages: 1175-1184

    • DOI

      10.1021/acs.joc.5b02697

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Synthesis of a Homochiral [2]Rotaxane from a BINOL-derived Macrocyclic Phenanthroline2015

    • Author(s)
      Saito, S.; Hirano, Y.; Mutoh, Y.; Kasama, T.
    • Journal Title

      CHEMISTRY LETTERS

      Volume: 44 Issue: 11 Pages: 1509-1511

    • DOI

      10.1246/cl.150693

    • NAID

      130005108083

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] A Macrocyclic Phenanthroline-Copper Complex with Less Steric Hindrance: Synthesis, Structure, and Application to the Synthesis of a [2]Rotaxane2015

    • Author(s)
      Shinichi Saito, Takanori Ohkubo, Yukari Yamazaki, Tatsuyuki Yokoyama, Yuichiro Mutoh, Ryu Yamasaki, and Takeshi Kasama
    • Journal Title

      BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN

      Volume: 88 Issue: 9 Pages: 1323-1330

    • DOI

      10.1246/bcsj.20150168

    • NAID

      130005099088

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Synthesis of [3]Rotaxanes by the Combination of Copper-Mediated Coupling Reaction and Metal-Template Approach2015

    • Author(s)
      Ryuto Hayashi, Yuichiro Mutoh, Takeshi Kasama, and Shinichi Saito
    • Journal Title

      JOURNAL OF ORGANIC CHEMISTRY

      Volume: 80 Issue: 15 Pages: 7536-7546

    • DOI

      10.1021/acs.joc.5b01120

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Synthesis of interlocked compounds utilizing the catalytic activity of macrocyclic phenanthroline-Cu complexes2015

    • Author(s)
      S. Saito
    • Journal Title

      JOURNAL OF INCLUSION PHENOMENA AND MACROCYCLIC CHEMISTRY

      Volume: 82 Issue: 3-4 Pages: 437-451

    • DOI

      10.1007/s10847-015-0511-1

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Synthesis of [3]Rotaxanes Utilizing the Catalytic Activity of Macrocyclic Phenanthroline-Cu Complex: Remarkable Effect of the Length of the Axle Precursor2015

    • Author(s)
      Yamashita, Y.; Mutoh, Y.; Yamasaki, R.; Kasama, T.; Saito, S.
    • Journal Title

      Chem.―Eur. J.

      Volume: 21 Issue: 5 Pages: 2139-2145

    • DOI

      10.1002/chem.201405090

    • Related Report
      2014 Research-status Report
    • Peer Reviewed
  • [Presentation] らせん構造を有するフェナントロリン誘導体の合成2017

    • Author(s)
      山﨑 由香里、武藤 雄一郎、斎藤 慎一
    • Organizer
      日本化学会第97春季年会
    • Place of Presentation
      慶應義塾大
    • Year and Date
      2017-03-17
    • Related Report
      2016 Annual Research Report
  • [Presentation] 面不斉[2]ロタキサンの合成とそのラセミ化2017

    • Author(s)
      望月 雄太、池谷 克彦、武藤 雄一郎、笠間 健嗣、斎藤 慎一
    • Organizer
      日本化学会第97春季年会
    • Place of Presentation
      慶應義塾大
    • Year and Date
      2017-03-16
    • Related Report
      2016 Annual Research Report
  • [Presentation] 銅触媒反応と金属テンプレート法を利用した[3]カテナンの合成2017

    • Author(s)
      伊藤 健、細谷 祥一、武藤 雄一郎、斎藤 慎一
    • Organizer
      日本化学会第97春季年会
    • Place of Presentation
      慶應義塾大
    • Year and Date
      2017-03-16
    • Related Report
      2016 Annual Research Report
  • [Presentation] Synthesis of Functionalized Homochiral [2]Rotaxanes from BINOL-derived Macrocyclic Phenanthroline2016

    • Author(s)
      Akihiro Shibuya, Yuichiro Mutoh, Shinichi Saito
    • Organizer
      15th Symposium on Chemical Approaches to Chirality
    • Place of Presentation
      東京理科大学
    • Year and Date
      2016-11-30
    • Related Report
      2016 Annual Research Report
  • [Presentation] 分子内薗頭型反応と金属テンプレート法を組み合わせた[3]カテナンの合成2016

    • Author(s)
      伊藤 健、武藤雄一郎、斎藤 慎一
    • Organizer
      第 63 回 有機金属化学討論会
    • Place of Presentation
      早稲田大学
    • Year and Date
      2016-09-14
    • Related Report
      2016 Annual Research Report
  • [Presentation] 面不斉を有する[2]ロタキサンの合成とその物性2016

    • Author(s)
      望月雄太、池谷克彦、武藤雄一郎、斎藤 慎一
    • Organizer
      第27回基礎有機化学討論会
    • Place of Presentation
      広島国際会議場(広島県広島市)
    • Year and Date
      2016-09-01
    • Related Report
      2016 Annual Research Report
  • [Presentation] ピロール構造で仕切られた[2]ロタキサンの合成とそのシャトリング2016

    • Author(s)
      斎藤 慎一、松岡 雄介、武藤 雄一郎、東屋 功、吉川 晶子、笠間 健嗣
    • Organizer
      第14回ホスト・ゲスト化学シンポジウム
    • Place of Presentation
      高知城ホール(高知県高知市)
    • Year and Date
      2016-06-04
    • Related Report
      2016 Annual Research Report
  • [Presentation] 巨大フェナントロリン誘導体の合成2016

    • Author(s)
      山崎 由香里、武藤 雄一郎、斎藤 慎一
    • Organizer
      日本化学会第96春季年会
    • Place of Presentation
      同志社大学(京都府京田辺市)
    • Year and Date
      2016-03-26
    • Related Report
      2015 Research-status Report
  • [Presentation] 分子内薗頭型反応を用いた[2]カテナンの合成2016

    • Author(s)
      伊藤 健、武藤 雄一郎、斎藤 慎一
    • Organizer
      日本化学会第96春季年会
    • Place of Presentation
      同志社大学(京都府京田辺市)
    • Year and Date
      2016-03-24
    • Related Report
      2015 Research-status Report
  • [Presentation] [2]ロタキサン-銅錯体の合成およびこれを用いたヘテロ[3]ロタキサンの合成2016

    • Author(s)
      山下 義明、武藤 雄一郎、山崎 龍、笠間 健嗣、斎藤 慎一
    • Organizer
      日本化学会第96春季年会
    • Place of Presentation
      同志社大学(京都府京田辺市)
    • Year and Date
      2016-03-24
    • Related Report
      2015 Research-status Report
  • [Presentation] ロタカテナン異性体の選択的合成2016

    • Author(s)
      林 竜人、SLAVIK Petr、武藤 雄一郎、笠間 健嗣、斎藤 慎一
    • Organizer
      日本化学会第96春季年会
    • Place of Presentation
      同志社大学(京都府京田辺市)
    • Year and Date
      2016-03-24
    • Related Report
      2015 Research-status Report
  • [Presentation] Synthesis of functionalized [2]rotaxanes from macrocyclic phenanthroline-Cu complexes2015

    • Author(s)
      S. Saito, K. Ikeyatsu, Y. Matsuoka, Y. Mutoh
    • Organizer
      2015 International Chemical Congress of Pacific Basin Societies
    • Place of Presentation
      Honolulu, USA
    • Year and Date
      2015-12-20
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] Synthesis of a [2]rotaxane from a less sterically hindered phenanthroline-copper complex2015

    • Author(s)
      Y. Yamazaki, T. Ohkubo, T. Yokoyama, Y. Mutoh, R. Yamasaki, T. Kasama, S. Saito
    • Organizer
      2015 International Chemical Congress of Pacific Basin Societies
    • Place of Presentation
      Honolulu, USA
    • Year and Date
      2015-12-19
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] Synthesis of rotacatenanes using transition metal catalysis and metal-template approach2015

    • Author(s)
      R. Hayashi, K. Wakatsuki, P. Slavik, R. Yamasaki, Y. Mutoh, T. Kasama, S. Saito
    • Organizer
      2015 International Chemical Congress of Pacific Basin Societies
    • Place of Presentation
      Honolulu, USA
    • Year and Date
      2015-12-18
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] Synthesis of [3]rotaxanes which consist of one ring and two axles2015

    • Author(s)
      Y. Yamashita, Y. Mutoh, R. Yamasaki, T. Kasama, S. Saito
    • Organizer
      2015 International Chemical Congress of Pacific Basin Societies
    • Place of Presentation
      Honolulu, USA
    • Year and Date
      2015-12-18
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] ピロール含有[2]ロタキサンの合成とそのシャトリング挙動2015

    • Author(s)
      松岡雄介、武藤雄一郎、東屋 功、吉川晶子、笠間健嗣、斎藤慎一
    • Organizer
      第26回基礎有機化学討論会
    • Place of Presentation
      愛媛大学・松山大学(愛媛県松山市)
    • Year and Date
      2015-09-25
    • Related Report
      2015 Research-status Report
  • [Presentation] アルキル基で置換された末端アルキンと銅錯体との反応による[2]ロタキサンの合成2015

    • Author(s)
      山崎由香里、丸山裕樹、武藤雄一郎、斎藤慎一
    • Organizer
      第 62 回 有機金属化学討論会
    • Place of Presentation
      関西大学千里山キャンパス(大阪府吹田市)
    • Year and Date
      2015-09-07
    • Related Report
      2015 Research-status Report
  • [Presentation] 大環状フェナントロリンー銅錯際を用いた[3]ロタキサンの合成2015

    • Author(s)
      山下義明、武藤雄一郎、山崎龍、笠間健嗣、斎藤慎一
    • Organizer
      第 62 回 有機金属化学討論会
    • Place of Presentation
      関西大学千里山キャンパス(大阪府吹田市)
    • Year and Date
      2015-09-07
    • Related Report
      2015 Research-status Report
  • [Presentation] 遷移金属触媒反応とテンプレート法を組み合わせたロタカテナン異性体の選択的合成2015

    • Author(s)
      林竜人、SLAVIK Petr、武藤雄一郎、笠間健嗣、斎藤慎一
    • Organizer
      第13回ホスト・ゲスト化学シンポジウム
    • Place of Presentation
      東北大学(宮城県仙台市)
    • Year and Date
      2015-06-06
    • Related Report
      2015 Research-status Report
  • [Presentation] ピロール含有ロタキサンの合成とその構造2015

    • Author(s)
      松岡 雄介・武藤 雄一郎・斎藤 慎一・笠間 健嗣
    • Organizer
      日本化学会第95春季年会
    • Place of Presentation
      千葉 日本大学
    • Year and Date
      2015-03-26
    • Related Report
      2014 Research-status Report
  • [Presentation] Synthesis of [3]Rotaxanes by the Combination of Transition Metal-catalyzed Coupling Reaction and Metal-template Method2015

    • Author(s)
      HAYASHI, Ryuto; MUTOH, Yuichiro; KASAMA, Takeshi; SAITO, Shinichi
    • Organizer
      日本化学会第95春季年会
    • Place of Presentation
      千葉 日本大学
    • Year and Date
      2015-03-26
    • Related Report
      2014 Research-status Report
  • [Presentation] BINOL骨格を有する大環状フェナントロリンを用いたホモキラル [2]ロタキサンの合成2015

    • Author(s)
      平野 義宏・武藤 雄一郎・斎藤 慎一
    • Organizer
      日本化学会第95春季年会
    • Place of Presentation
      千葉 日本大学
    • Year and Date
      2015-03-26
    • Related Report
      2014 Research-status Report
  • [Presentation] Synthesis of [3] rotaxanes from the [2]rotaxane-Cu Complex2015

    • Author(s)
      YAMASHITA, Yoshiaki; MUTOH, Yuichiro; YAMASAKI, Ryu; KASAMA, Takeshi; SAITO, Shinichi
    • Organizer
      日本化学会第95春季年会
    • Place of Presentation
      千葉 日本大学
    • Year and Date
      2015-03-26
    • Related Report
      2014 Research-status Report
  • [Presentation] ピロール含有ロタキサンの合成とその動的挙動2014

    • Author(s)
      松岡雄介、武藤雄一郎、斎藤慎一
    • Organizer
      第68回有機合成化学協会関東支部シンポジウム
    • Place of Presentation
      新潟大学
    • Year and Date
      2014-11-29
    • Related Report
      2014 Research-status Report
  • [Presentation] Synthesis of a Homochiral Rotaxane from a BINOL-derived Macrocyclic Phenanthroline2014

    • Author(s)
      Yoshihiro Hirano, Yuichiro Mutoh, Shinichi Saito
    • Organizer
      13th Symposium on Chemical Approaches to Chirality
    • Place of Presentation
      家の光会館、東京
    • Year and Date
      2014-11-12
    • Related Report
      2014 Research-status Report
  • [Presentation] 大環状銅錯体の触媒活性を利用した高次インターロック化合物の創製2014

    • Author(s)
      斎藤 慎一
    • Organizer
      第15回 リング・チューブ超分子研究会シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2014-10-28
    • Related Report
      2014 Research-status Report
    • Invited
  • [Presentation] 金属触媒反応を用いた[2]ロタキサン合成における大環状フェナントロリン分子のサイズ限界について2014

    • Author(s)
      池谷 克彦、武藤 雄一郎、斎藤 慎一
    • Organizer
      第15回 リング・チューブ超分子研究会シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2014-10-27
    • Related Report
      2014 Research-status Report
  • [Presentation] 遷移金属触媒反応と金属テンプレート法を組み合わせることによる[3]ロタキサンの合成2014

    • Author(s)
      林 竜人、武藤 雄一郎、笠間 健嗣、斎藤 慎一
    • Organizer
      第15回 リング・チューブ超分子研究会シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2014-10-27
    • Related Report
      2014 Research-status Report
  • [Presentation] アルキル基で置換された末端アルキンを用いるロタキサンの合成2014

    • Author(s)
      山﨑由香里・武藤雄一郎・斎藤慎一
    • Organizer
      第4回CSJ化学フェスタ
    • Place of Presentation
      東京
    • Year and Date
      2014-10-16
    • Related Report
      2014 Research-status Report
  • [Presentation] トポロジカルキラリティーを有する[2]ロタキサンの合成とその光学分割2014

    • Author(s)
      池谷 克彦、山崎 龍、武藤 雄一郎、笠間 健嗣、斎藤 慎一
    • Organizer
      第25回基礎有機化学討論会
    • Place of Presentation
      仙台
    • Year and Date
      2014-09-18
    • Related Report
      2014 Research-status Report
  • [Presentation] Application of the Metal-Mediated Reactions for the Synthesis of Complex Interlocked Compounds2014

    • Author(s)
      Shinichi SAITO, Ryuto HAYASHI, Yoshiaki YAMASHITA, Ryu YAMASAKI, and Yuichiro MUTOH
    • Organizer
      XXVI International Conference on Organometallic Chemistry (ICOMC 2014)
    • Place of Presentation
      札幌
    • Year and Date
      2014-07-18
    • Related Report
      2014 Research-status Report
  • [Presentation] 金属触媒反応と金属テンプレート法を利用したロタカテナンおよび[3]ロタキサンの合成2014

    • Author(s)
      斎藤 慎一、林 竜人、若月 公太、山崎 龍、武藤 雄一郎、笠間 健嗣
    • Organizer
      第12回ホスト・ゲスト化学シンポジウム
    • Place of Presentation
      東京 東京工業大学
    • Year and Date
      2014-06-01
    • Related Report
      2014 Research-status Report
  • [Presentation] ロタキサン-銅錯体の触媒活性を利用したヘテロ[3]ロタキサンの合成2014

    • Author(s)
      山下義明、山崎龍、武藤雄一郎、笠間健嗣、斎藤慎一
    • Organizer
      第12回ホスト・ゲスト化学シンポジウム
    • Place of Presentation
      東京 東京工業大学
    • Year and Date
      2014-06-01
    • Related Report
      2014 Research-status Report
  • [Remarks]

    • URL

      http://www.rs.kagu.tus.ac.jp/sslab/publications.htm

    • Related Report
      2015 Research-status Report

URL: 

Published: 2014-04-04   Modified: 2018-03-22  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi