| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Outline of Final Research Achievements |
Many GTP coupled receptors exits as homodetic and heterodetic dimeric forms on the biological membrane and the functions of two protomers of dimeric GPCR have not been elucidated. To understand the functions of protomers of formyl peptide receptors, heterodetic dimeric peptides of peptides with the high selectivities for two receptor subtypes were synthesized. From the results of biological assays, dimeric peptides interact with the two protomers.
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