Polyfunctional carotenoid synthesis toward elucidation of highly efficient energy transfer by marine photosynthetic organisms
Project/Area Number |
26410183
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Bio-related chemistry
|
Research Institution | Osaka City University |
Principal Investigator |
|
Co-Investigator(Kenkyū-buntansha) |
勝村 成雄 大阪市立大学, 大学院理学研究科, 客員教授 (70047364)
|
Co-Investigator(Renkei-kenkyūsha) |
HASHIMOTO HIDEKI 大阪市立大学, 複合先端研究機構, 教授 (50222211)
|
Project Period (FY) |
2014-04-01 – 2017-03-31
|
Project Status |
Completed (Fiscal Year 2016)
|
Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
|
Keywords | フコキサンチン / 海洋光合成初期過程 / 超分子複合体 / ICT準位 / 超効率的エネルギー伝達 / パラセントロン / 光合成初期過程 / 両官能性C5ジエン / クロスカップリング / スフェロイデノン / 両官能性C5ジエンユニット / クロスカップリング反応 / 両官能性ジエン / カロテノイド / エネルギー伝達 |
Outline of Final Research Achievements |
The highly oxidized marine carotenoid fucoxanthin is a representative light-harvesting pigment for photosynthesis in the sea. This carotenoid exhibits exceptionally high-energy transfer efficiency (>85%) in the fucoxanthin -chlorophyll a-protein (FCP) complex. In this project, we succeeded in the synthesis of natural apocarotenoid paracentrone, which was a one cyclohexane-moiety free analogue of fucoxanthin, and its derivatives by the sequential cross coupling reactions of novel bifunctional C5 diene units as key building brocks. The ultrafast time resolved spectra measurement of paracentrone revealed that this carotenoid possessed the intramolecular charge transfer (ICT) state, which contributed to the remarkably high light-harvesting efficiency in marine photosynthesis. Toward elucidation of the mechanism of this super function by marine photosynthetic organisms, reconstitution of the corresponding super complex containing paracentrone is in progress.
|
Report
(4 results)
Research Products
(39 results)
-
-
-
-
[Journal Article] Spectroscopic investigation of the carotenoid deoxyperidinin: direct observation of the forbidden S0 → S1 transition2016
Author(s)
Greco, J. A., LaFountain, A. M., Kinashi, N., Shinada, T., Sakaguchi, K., Katsumura, S., S., Magdaong, S., Niedzwiedzki, D.M.R., Birge, R.H., Frank, A.
-
Journal Title
The Journal of Physiological Chemistry B
Volume: 120
Issue: 10
Pages: 2731-2734
DOI
Related Report
Peer Reviewed / Open Access / Int'l Joint Research
-
-
-
[Journal Article] Excited state properties of a short π-electron conjugated peridinin analogue2014
Author(s)
Magdaong, N. M.; Niedzwiedzki, D. M.; Greco, J. A.; Liu, H.; Yano, K.; Kajikawa, T.; Sakaguchi, K.; Katsumura, S.; Birge, R. R.; Frank, H. A.
-
Journal Title
Chem. Phys. Lett.
Volume: 593
Pages: 132-139
Related Report
Peer Reviewed
-
-
-
-
-
-
-
[Presentation] Energy-transfer efficiency of fucoxanthin reconstituted into the light-harvesting 1 complex from a purple photosynthetic bacterium Rhodospirillum rubrum G9+2016
Author(s)
N. Yukihira, Y. Sugai, M. Fujiwara, C. Uragami, D. Kosumi, K. Sakaguchi, S. Katsumura, A. T. Gardiner, R. J. Cogdell, and H. Hashimoto
Organizer
The 23rd International SPACC (The Society of Pure and Applied Coordination Chemistry) Symposium; Functional complexes and their new applications
Place of Presentation
Okayama University of Science (Okayama, Okayama City)
Year and Date
2016-11-21
Related Report
Int'l Joint Research
-
[Presentation] Total Synthesis of Paracentrone2016
Author(s)
Y. Nishioka, Y. Yano, N. Kinashi, N. Oku, Y. Toriyama, S. Katsumura, T. Shinada, K. Sakaguchi
Organizer
The 10th International Symposium on Integrated Synthesis (ISONIS-10)
Place of Presentation
Awaji Yumebutai International Conference Center (Hyogo, Awaji City)
Year and Date
2016-11-18
Related Report
Int'l Joint Research
-
[Presentation] Total Synthesis of Paracentrone2016
Author(s)
Y. Nishioka, Y. Yano, N. Kinashi, N. Oku, Y. Toriyama, S. Katsumura, T. Shinada, K. Sakaguchi
Organizer
International Symposium on Natural Products for the Future 2016 Tokushima
Place of Presentation
Tokushima Bunri University (Tokushima, Tokushima City)
Year and Date
2016-09-01
Related Report
Int'l Joint Research
-
-
-
-
-
-
-
[Presentation] Total Synthesis of Paracentrone2016
Author(s)
Y. Nishioka, Y. Yano, N. Kinashi, N. Oku, Y. Toriyama, S. Katsumura, T. Shinada, K. Sakaguchi
Organizer
The 2016 OCARINA Annual International Meeting
Place of Presentation
Osaka City University, Media Center, Osaka (Osaka city)
Year and Date
2016-03-17
Related Report
Int'l Joint Research
-
-
[Presentation] Polyfunctional carotenoid synthesis via one-pot strategy: Toward elucidation of highly efficient energy transfer by marine photosynthetic organisms2015
Author(s)
K. Sakaguchi, T. Kajikawa, S. Hananoki, N. Kinashi, D. Kosumi, H. Hashimoto, H. A. Frank, T. Shinada, S. Katsumura
Organizer
2015 International Chemical Congress of Pacific Basin Societies (PACIFICHEM 2015)
Place of Presentation
Hawaii Convention Center, Honolulu, Hawaii, USA
Year and Date
2015-12-12
Related Report
Int'l Joint Research
-
[Presentation] Total Synthesis of Paracentrone2015
Author(s)
N. Oku, Y. Nishioka, Y. Yano, N. Kinashi, S. Katsumura, T. Shinada, and K. Sakaguchi
Organizer
The 19th Osaka City University International Workshop on Advanced Molecular Materials Science
Place of Presentation
Osaka City University, Media Center, Osaka (Osaka city)
Year and Date
2015-11-12
Related Report
Int'l Joint Research
-
-
-
-
-
-
-
-
-
-
-
-
-