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A Study on Numerical Simulation of Alveolar Bone Regeneration and Angiogenesis

Research Project

Project/Area Number 26420202
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Intelligent mechanics/Mechanical systems
Research InstitutionKyushu Institute of Technology

Principal Investigator

Nagayama Katsuya  九州工業大学, 大学院情報工学研究院, 教授 (70363398)

Co-Investigator(Renkei-kenkyūsha) MATSUO Masato  神奈川歯科大学, 大学院歯学研究科, 教授 (30190416)
Project Period (FY) 2014-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2016: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2015: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2014: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
KeywordsNumerical Simulation / Alveolor Bone / Regeneration / Angiogenesis / Alveolar Bone / バイオメカニクス / シミュレーション / 歯槽骨 / 血管新生
Outline of Final Research Achievements

In the study of implant treatment, alveolar bone regeneration is required due to an increase in nutritional supply accompanying angiogenesis, but the evaluation of bone formation is dependent on experiments and has not been predicted by analysis. The overall concept of this study is to construct a numerical simulation to predict the degree of surrounding alveolar bone formation and visualize it.In the procedure, a fundamental series of analytical models was completed by first constructing the basic model of analysis, applying it to the formation of young bone from extraction of the tooth, and analyzing the trabecular bone formation.The method used a particle model that can handle complicated phenomena. Although the basic model has been completed, there are many parameters in the analysis, and optimization and verification of them are subjects in the future. We hope to contribute to the improvement of the quality of vascular implant treatment in the future.

Report

(4 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • Research Products

    (12 results)

All 2016 2015 2014 Other

All Journal Article (2 results) (of which Peer Reviewed: 1 results,  Acknowledgement Compliant: 1 results) Presentation (7 results) (of which Int'l Joint Research: 1 results) Remarks (3 results)

  • [Journal Article] Numerical Simulation of Alveolar Bone Regeneration and Angiogenesis - Building a Coupled Model -2015

    • Author(s)
      A. Kitamoto, Katsuya Nagayama, and Masato Matsuo
    • Journal Title

      Proceedings of The 6th TSME International Conference on Mechanical Engineering

      Volume: BME007

    • NAID

      120006664882

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] 歯槽骨再生と血管新生の数値シミュレーション―応力・拡散による骨形成―2015

    • Author(s)
      北本旭央,永山勝也,松尾雅斗
    • Journal Title

      日本機械学会(No-15-40) 第26回バイオフロンティア講演会論文集

      Volume: B214 Pages: 127-128

    • Related Report
      2015 Research-status Report
  • [Presentation] Numerical Simulation of Alveolar Bone Regeneration and Angiogenesis - Trabecular Bone Formation -2016

    • Author(s)
      Y. Fukuda, Katsuya Nagayama and Masato Matsuo
    • Organizer
      The 7th TSME International Conference on Mechanical Engineering
    • Place of Presentation
      Thailand
    • Year and Date
      2016-12-13
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 歯槽骨再生と血管新生の数値シミュレーション-骨梁形成まで-2016

    • Author(s)
      福田 圭寿,永山勝也,松尾雅斗
    • Organizer
      機械学会年次大会
    • Place of Presentation
      九州大学
    • Related Report
      2016 Annual Research Report
  • [Presentation] 粒子モデルによる歯槽骨再生と血管新生の数値シミュレーション ―応力因子の導入―2015

    • Author(s)
      北本旭央,永山勝也,松尾雅斗
    • Organizer
      日本機械学会 九州支部第68期総会講演会論文集
    • Place of Presentation
      福岡大学
    • Year and Date
      2015-03-13
    • Related Report
      2014 Research-status Report
  • [Presentation] Numerical Simulation of Alveolar Bone Regeneration and Angiogenesis - Implementing the Stress Factor -2015

    • Author(s)
      Akio Kitamoto, Katsuya Nagayama, Masato Matuo
    • Organizer
      The Third BMIRC International Symposium for Virtual Physiological Human
    • Place of Presentation
      Kyushu Institute of Technology, Fukuoka, Japan
    • Year and Date
      2015-03-05 – 2015-03-06
    • Related Report
      2014 Research-status Report
  • [Presentation] Particle Simulation of Alveolar Bone Regeneration and Angiogenesis -treated with Platelet-Rich Plasma2014

    • Author(s)
      Akio Kitamoto, Katsuya Nagayama, Masato Matuo
    • Organizer
      2014 World Congress on Preventive and Regenerative Medicine
    • Place of Presentation
      Chientan Youth Activity Center, Taipei, Taiwan
    • Year and Date
      2014-11-04 – 2014-11-07
    • Related Report
      2014 Research-status Report
  • [Presentation] Particle Simulation of Alveolar Bone Regeneration and Angiogenesis -Effect of stress on bone formation2014

    • Author(s)
      Katsuya Nagayama, Akio Kitamoto, Masato Matuo
    • Organizer
      2014 World Congress on Preventive and Regenerative Medicine
    • Place of Presentation
      Chientan Youth Activity Center, Taipei, Taiwan
    • Year and Date
      2014-11-04 – 2014-11-07
    • Related Report
      2014 Research-status Report
  • [Presentation] Particle Simulation of Alveolar Bone Regeneration and Angiogenesis-Study on Stress Model-2014

    • Author(s)
      Akihiro Kitamoto,Katsuya Nagayama, Masato Matsuo
    • Organizer
      International Conference on Biofabrication
    • Place of Presentation
      PosTech Pohang Korea
    • Year and Date
      2014-09-28 – 2014-09-30
    • Related Report
      2014 Research-status Report
  • [Remarks] 再生医療支援の画像処理・数値解析

    • URL

      http://www.nl.mse.kyutech.ac.jp/publication.htm#g

    • Related Report
      2016 Annual Research Report
  • [Remarks] 永山研究室

    • URL

      http://www.nl.mse.kyutech.ac.jp/08_regen-med.htm

    • Related Report
      2015 Research-status Report
  • [Remarks] 再生医療支援の数値解析

    • URL

      http://www.nl.mse.kyutech.ac.jp/08_regen-med.htm

    • Related Report
      2014 Research-status Report

URL: 

Published: 2014-04-04   Modified: 2018-03-22  

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