| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Outline of Final Research Achievements |
The present study examined the role of dopaminergic functions in the lateral hypothalamus (LH) in the regulation of feeding behavior. The results in the present study have indicated that dopamine neurons in the LH are activated by food intake, which inhibits food intake by activating dopamine D1 and D2 receptors. In addition, it is suggested that dopamine D1 and D2 receptors in the LH have an inhibitory role in the regulation of feeding behavior through agouti-related peptide (AgRP) / neuropeptide Y (NPY) neurons and orexin neurons, respectively.
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