Development of NGS Data Analysis Softwares Considering the Data Profile of Each Platform
Project/Area Number |
26430199
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
System genome science
|
Research Institution | Maebashi Institute of Technology |
Principal Investigator |
|
Project Period (FY) |
2014-04-01 – 2017-03-31
|
Project Status |
Completed (Fiscal Year 2016)
|
Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
|
Keywords | 次世代シーケンサー / イルミナ / Gef-seq / 相同組換変異解析 / 転写因子 / 解析プログラム開発 / エラープロファイル / ゲノムアセンブル / マッピング / バイオインフォマティクス / 相同組換え / 変異解析 / 機器特異的エラープロファイル / Illumina / 相同組み替え / 酵母 / プログラム開発 / 微生物ゲノム / ChIP-seq |
Outline of Final Research Achievements |
I have been developing a mapping program "maps" suite for next generation sequencing. I was able to achieve the following accomplishment during the 3 years period. (1) I have contributed the establishment of Gef-seq (Genome footprint sequence) analysis method, which is an improved method of ChIP-seq analysis, by preparing the computational analysis pipeline. (2) I continued the error-profile analysis of Illumina Next generation sequencer. (3) I have contributed the analysis of homologous/non-homologous rearrangements occuring in a part of organera genomes. (4) I contributed a comparative genome analysis of several yeast strains by genome assembling. For (1), we published a apaper and made our program public, and preparing another manuscript to describe the protocol. For (2), I made a couple of presentations. For (3) and (4), we are preparing for a publication.
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Report
(4 results)
Research Products
(5 results)