| Project/Area Number |
26440117
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Developmental biology
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| Research Institution | Toyo University (2016)
The University of Tokyo (2014-2015) |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
MORIYAMA Yuuta 東京大学, 分子細胞生物学研究所, 特別研究員 (40646212)
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| Research Collaborator |
KASUGAI Takashi
YOSHIDA Masa-aki
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2015: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2014: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | 頭足類 / 心臓 / 発生 / 形態進化 / 器官形成 |
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| Outline of Final Research Achievements |
Cephalopod has three hearts; one is a systemic heart and others are branchial hearts. The systemic heart has a role to circulate blood flow to the entire body, while the branchial heart is an organ to send the blood specifically to the branchial. Although a unique circulation system of cephalopod is well known, the developmental process of these hearts in the cephalopod embryo is still unclear.
In this study, the squid homologues to cardiac specific transcription factor genes in vertebrate were isolated to examine the expression patterns in heart development by using Idiosepius paradoxus embryos. The cardiac transcription factor genes were specifically expressed in the presumptive cardiac region in squid embryo suggesting that both systemic and branchial hearts would be derived from the same cardiac field.
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