Analysis of cardiac field development in a model squid, Idiosepius paradoxus
Project/Area Number |
26440117
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Developmental biology
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Research Institution | Toyo University (2016) The University of Tokyo (2014-2015) |
Principal Investigator |
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Co-Investigator(Renkei-kenkyūsha) |
MORIYAMA Yuuta 東京大学, 分子細胞生物学研究所, 特別研究員 (40646212)
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Research Collaborator |
KASUGAI Takashi
YOSHIDA Masa-aki
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Project Period (FY) |
2014-04-01 – 2017-03-31
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Project Status |
Completed (Fiscal Year 2016)
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Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2015: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2014: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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Keywords | 頭足類 / 心臓 / 発生 / 形態進化 / 器官形成 |
Outline of Final Research Achievements |
Cephalopod has three hearts; one is a systemic heart and others are branchial hearts. The systemic heart has a role to circulate blood flow to the entire body, while the branchial heart is an organ to send the blood specifically to the branchial. Although a unique circulation system of cephalopod is well known, the developmental process of these hearts in the cephalopod embryo is still unclear. In this study, the squid homologues to cardiac specific transcription factor genes in vertebrate were isolated to examine the expression patterns in heart development by using Idiosepius paradoxus embryos. The cardiac transcription factor genes were specifically expressed in the presumptive cardiac region in squid embryo suggesting that both systemic and branchial hearts would be derived from the same cardiac field.
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Report
(4 results)
Research Products
(31 results)
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[Journal Article] Sall1 transiently marks undifferentiated heart precursors and regulates their fate2016
Author(s)
Yuika Morita,Peter Andersen,Akitsu Hotta,Yuko Tsukahara,Noriko Sasagawa,Naoko Hayashida,Chizuko Koga,Misato Nishikawa,Yumiko Saga,Sylvia M. Evans, Kazuko Koshiba-Takeuchi,Ryuichi Nishinakamura,Yoshinori Yoshida,Chulan Kwon,Jun K. Takeuchi
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Journal Title
Journal of Molecular and Cellular Cardiology
Volume: 192
Pages: 158-162
DOI
Related Report
Peer Reviewed / Open Access / Int'l Joint Research
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[Presentation] 心臓運命をプログラムする因子とその発展性2015
Author(s)
森田唯加, 堀田秋津, Peter Andersen, 小川英知, 吉田善紀, 塚原由布子, 黒川洵子, 相賀裕美子, Sylvia Evans, 西中村隆一, 小柴和子, Chulan Kwon, 竹内 純
Organizer
第38回日本分子生物学会年会
Place of Presentation
神戸ポートアイランド(兵庫県・神戸市)
Year and Date
2015-12-04
Related Report
Invited
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