Analysis of post-traslational modification of GAF1 complex in GA signaling
Project/Area Number |
26440148
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Plant molecular biology/Plant physiology
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Research Institution | Hiroshima University |
Principal Investigator |
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Project Period (FY) |
2014-04-01 – 2017-03-31
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Project Status |
Completed (Fiscal Year 2016)
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Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2015: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2014: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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Keywords | 植物ホルモン / 信号伝達 / 転写因子 / 成長生理 / ジベレリン / 転写制御 / 翻訳後修飾 / 転写調節 |
Outline of Final Research Achievements |
Gibberellins (GAs) are essential regulates of plant development, including seed germination, stem elongation and flowering. In GA signaling, DELLA protein are negative regulators and degraded by GA. We identified a DELLA-binding transcription factor GAF1. We found that GAF1 interact with corepressor TOPLESS RELATED (TPR) and that DELLAs and TPR act as coactivator and a corepressor of GAF1, respectively. GA converts the GAF1 complex from transcriptional activator to repressor via degradation of DELLAs. This complex is a major components in GA feedback regulation. We found that post-translational modification of GAF1 complex might be involved in GA signaling.
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Report
(4 results)
Research Products
(12 results)
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[Journal Article] Binding of GID1 to DELLAs Promotes Dissociation of GAF1 from DELLA in GA Dependent Manner2015
Author(s)
Fukazawa, J., Ito, T., Yoshida, M., Kamiya, Y., Yamaguchi, S., and Takahashi, Y.
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Journal Title
Plant Signaling and Behavior
Volume: 10
Issue: 10
Pages: e1052923-e1052923
DOI
Related Report
Peer Reviewed / Open Access / Acknowledgement Compliant
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