| Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2015: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2014: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Outline of Final Research Achievements |
Gibberellins (GAs) are essential regulates of plant development, including seed germination, stem elongation and flowering. In GA signaling, DELLA protein are negative regulators and degraded by GA. We identified a DELLA-binding transcription factor GAF1. We found that GAF1 interact with corepressor TOPLESS RELATED (TPR) and that DELLAs and TPR act as coactivator and a corepressor of GAF1, respectively. GA converts the GAF1 complex from transcriptional activator to repressor via degradation of DELLAs. This complex is a major components in GA feedback regulation. We found that post-translational modification of GAF1 complex might be involved in GA signaling.
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