| Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2015: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
|
|---|
| Outline of Final Research Achievements |
This work investigated the gene regulatory mechanism of leaf development in Arabidopsis thaliana. The genetic analysis of miR319 and its target TCP gene families demonstrated the roles of these genes in the formation of leaf serrations and cotyledon boundary. Mutations in MIR319 genes inhibited the formation of leaf serrations and the cotyledon boundary in association with regulator genes of the boundary morphogenesis. In contrast, loss-of-function mutations in these TCP genes induced the formation of serrated leaves in addition to changes in the levels of their downstream gene expression. This works also found that quintuple mutant for class I TCP genes induced irrgularity in its leaf form. Overall, combinations of mutations in TCP transcription factor genes in Arabidopsis thaliana generate various leaf forms.
|
