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Diversity and molecular evolution of aquaporins in amphibians

Research Project

Project/Area Number 26440165
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Morphology/Structure
Research InstitutionShizuoka University

Principal Investigator

Suzuki Masakazu  静岡大学, 理学部, 教授 (60280913)

Co-Investigator(Kenkyū-buntansha) 宇根 ユミ  麻布大学, 獣医学部, 教授 (40160303)
Research Collaborator Hillyard Stanley D.  University of Nevada, Professor
Youssoufou Ouedraogo  University of Ouagadougou, Lecturer
Project Period (FY) 2014-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywordsアクアポリン / 両生類 / 無尾類 / 有尾類 / 水輸送 / 国際研究者交流
Outline of Final Research Achievements

Our study suggested that in some African toads, AQP6/a2U may be involved in water reabsorption from the urinary bladder. Further, our analysis of the skin of tropical clawed frogs suggested that AQP6/a2S may play an important role in the acclimation of this species to dry environments. It was also suggested that the molecular machinery for antidiuretic hormone-regulated transepithelial water transport may originate in a common ancestor to anurans and urodeles.

Report

(4 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • Research Products

    (31 results)

All 2017 2016 2015 2014 Other

All Int'l Joint Research (4 results) Journal Article (8 results) (of which Peer Reviewed: 6 results,  Acknowledgement Compliant: 2 results) Presentation (13 results) (of which Int'l Joint Research: 1 results,  Invited: 3 results) Book (6 results)

  • [Int'l Joint Research] ネバダ大学(米国)

    • Related Report
      2016 Annual Research Report
  • [Int'l Joint Research] ワガドゥグー大学(ブルキナファソ)

    • Related Report
      2016 Annual Research Report
  • [Int'l Joint Research] ネバダ大学(米国)

    • Related Report
      2015 Research-status Report
  • [Int'l Joint Research] ワガドゥグー大学(ブルキナファソ)

    • Related Report
      2015 Research-status Report
  • [Journal Article] Molecular machinery for vasotocin-dependent transepithelial water movement in amphibians: aquaporins and evolution2015

    • Author(s)
      M. Suzuki, Y. Shibata, Y. Ogushi, & R. Okada
    • Journal Title

      The Biological Bulletin

      Volume: 229 Pages: 109-119

    • Related Report
      2015 Research-status Report
    • Peer Reviewed
  • [Journal Article] Molecular cloning of cDNA encoding an aquaglyceroporin, AQP-h9, in the Japanese tree frog, Hyla japonica: possible roles of AQP-h9 as a glycerol transporter in freeze tolerance2015

    • Author(s)
      Hirota A, Takiya Y, Sakamoto J, Shiojiri N, Suzuki M, Tanaka S, Okada R.
    • Journal Title

      Zoolog Sci.

      Volume: 32 Issue: 3 Pages: 296-306

    • DOI

      10.2108/zs140246

    • Related Report
      2015 Research-status Report 2014 Research-status Report
    • Peer Reviewed
  • [Journal Article] Aquaporins and water homeostasis in Xenopus2015

    • Author(s)
      Y. Shibata & M. Suzuki
    • Journal Title

      Advances in Animal Science and Zoology

      Volume: 7

    • Related Report
      2014 Research-status Report
    • Acknowledgement Compliant
  • [Journal Article] Molecular and cellular characterization of urinary bladder-type aquaporin in Xenopus laevis2014

    • Author(s)
      Yuki Shibata, Izumi Katayama, Yuji Ogushi, Takashi Nakakura, Reiko Okada, Shigeyasu Tanaka, Masakazu Suzuki.
    • Journal Title

      Gen Comp Endocrinol.

      Volume: 222 Pages: 11

    • DOI

      10.1016/j.ygcen.2014.09.001

    • URL

      https://pure.teikyo.jp/en/publications/ebee320d-4860-43d8-8d2f-dc47031c40fb

    • Related Report
      2015 Research-status Report 2014 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Gene expression, function, and diversity of Nkx2-4 in the rainbow trout, Oncorhynchus mykiss2014

    • Author(s)
      Youj Uemae, Joe Sakamoto, Yoshie Hidaka, Ai Hiratsuka, Takao Susa, Yukio Kato, Masakazu Suzuki.
    • Journal Title

      Gen Comp Endocrinol.

      Volume: 206 Pages: 193

    • DOI

      10.1016/j.ygcen.2014.07.007

    • Related Report
      2014 Research-status Report
    • Peer Reviewed
  • [Journal Article] Gene expression and localization of two types of AQP5 in Xenopus tropicalis under hydration and dehydration.2014

    • Author(s)
      Yuki Shibata, Junya Hara, Takahiro Sano, Masakazu Suzuki, Reiko Okada, Hiroshi Mochida, and Shigeyasu Tanaka.
    • Journal Title

      Am J Physiol Regul lntegr Comp Physiol

      Volume: (In press) Issue: 1 Pages: R44-R56

    • DOI

      10.1152/ajpregu.00186.2013

    • Related Report
      2014 Research-status Report
    • Peer Reviewed
  • [Journal Article] Novel vasotocin-regulated aquaporins expressed in the ventral skin of semigaquatic anuran amphibians: evolution of cutaneous water-absorbing mechanisms.2014

    • Author(s)
      Saitoh, Y., Ogushi, Y., Shibata, Y., Okada, R., Tanaka, S., Suzuki, M
    • Journal Title

      Endocrinology

      Volume: in press Issue: 6 Pages: 2166-2177

    • DOI

      10.1210/en.2013-1928

    • Related Report
      2014 Research-status Report
    • Peer Reviewed
  • [Journal Article] 水中および乾燥順応時のネッタイツメガエル(Xenopus tropicalis)における2種類のAQP5(AQP-xt5aおよびAQP-xt5b)の遺伝子発現と局在.2014

    • Author(s)
      柴田侑毅, 鈴木雅一
    • Journal Title

      比較内分泌学

      Volume: 40 Pages: 128-130

    • NAID

      130004700506

    • Related Report
      2014 Research-status Report
  • [Presentation] 両生類の環境適応におけるアクアポリンの役割2017

    • Author(s)
      鈴木雅一
    • Organizer
      第3回「水シグナリングの分子動態から病態へ」研究会
    • Place of Presentation
      アオッサ (福井県福井市)
    • Year and Date
      2017-03-07
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] Furhter characterization of anuran-like aquaporins in the urinary bladder of urodeles, Notopthalmus viridenscens and Cynops phrrhogaster2016

    • Author(s)
      S. Hillyard, Y. Shibata, R. Ishii, T. Nagai, M. Suzuki
    • Organizer
      Experimental Biology 2016
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2016-04-02
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] カエルツボカビ感染が皮膚水吸収に与える影響2016

    • Author(s)
      嘉手苅 将, 柴田 侑毅, 常盤 俊大, 鈴木 雅一, 宇根 有美
    • Organizer
      第3回獣医病理学専門家協会学術集会
    • Place of Presentation
      三鷹市公会堂(東京・三鷹市)
    • Year and Date
      2016-03-29
    • Related Report
      2015 Research-status Report
  • [Presentation] 両生類の水代謝2016

    • Author(s)
      鈴木雅一
    • Organizer
      日本比較内分泌学会大会
    • Place of Presentation
      北里大学 (神奈川県相模原市)
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] 両生類における新規AQPの同定及びAQPの分子進化2015

    • Author(s)
      石井凌, 柴田侑毅, 内山実, 嘉手苅将, 常盤俊大, 宇根有美, スタンリー・ヒルヤード, 長井孝紀, 鈴木雅一
    • Organizer
      日本動物学会第86回新潟大会
    • Place of Presentation
      朱鷺メッセ(新潟・新潟市)
    • Year and Date
      2015-09-17
    • Related Report
      2015 Research-status Report
  • [Presentation] カエルツボカビ(Batrachochytrium dendrobatidis)が無尾両生類の皮膚を介した水透過性に与える影響2014

    • Author(s)
      柴田侑毅, 嘉手苅将, 常盤俊大, 宇根有美, 鈴木雅一
    • Organizer
      平成26年度 日本動物学会中部支部大会能登大会
    • Place of Presentation
      金沢大学 環日本海域環境研究センター 臨海実験施設、能登
    • Year and Date
      2014-11-22 – 2014-11-24
    • Related Report
      2014 Research-status Report
  • [Presentation] Molecular evolution and physiological roles of aquaporins expressed in anuran osmoregulatory organs2014

    • Author(s)
      Masakazu Suzuki, Yuki Shibata, Reiko Okada
    • Organizer
      The 8th International Symposium on Amphibian and Reptilian Endocrinology and Neurobiology
    • Place of Presentation
      National Institute for Basic Biology, Okazaki, Japan
    • Year and Date
      2014-11-07 – 2014-11-09
    • Related Report
      2014 Research-status Report
    • Invited
  • [Presentation] Spatial and temporal expression of aquaporins, AQP2 and AQP3, in the kidney during metamorphosis of the tree frog, Hyla japonica2014

    • Author(s)
      Takayuki Ueno , Yuki Shibata, Haruna Sano, Shiori Yamashita, Masakazu Suzuki
    • Organizer
      The 8th International Symposium on Amphibian and Reptilian Endocrinology and Neurobiology
    • Place of Presentation
      National Institute for Basic Biology, Okazaki, Japan
    • Year and Date
      2014-11-07 – 2014-11-09
    • Related Report
      2014 Research-status Report
  • [Presentation] Molecular cloning of cDNA encoding Na+/I- symporter from the brown hagfish, Paramyxine atami2014

    • Author(s)
      Naoya Segi, Tetsuya Kobayashi, Yasuyuki Muramatsu, Yoichi Kondo, Masakazu Suzuki
    • Organizer
      第39回日本比較内分泌学会大会 (2014年11月)
    • Place of Presentation
      岡崎コンファレンスセンター、岡崎
    • Year and Date
      2014-11-07 – 2014-11-09
    • Related Report
      2014 Research-status Report
  • [Presentation] Expression and function of aquaporins in Xenopus tropicalis under hydration and dehydration2014

    • Author(s)
      Yuki Shibata, Takahiro Sano, Reiko Okada, Shigeyasu Tanaka, Masakazu Suzuki
    • Organizer
      第39回日本比較内分泌学会大会
    • Place of Presentation
      岡崎コンファレンスセンター、岡崎
    • Year and Date
      2014-11-07 – 2014-11-09
    • Related Report
      2014 Research-status Report
  • [Presentation] Anuran-specific aquaporin 2 ortholog in a urodele, evidence for early gene duplication in amphibian evolution2014

    • Author(s)
      Yuki Shibata, Masakazu Suzuki, Takatoshi Nagai, Stanley Hillyard
    • Organizer
      APS fall meeting
    • Place of Presentation
      Town & Country Resort & Convention Center, San Diego, CA
    • Year and Date
      2014-10-05 – 2014-10-08
    • Related Report
      2014 Research-status Report
  • [Presentation] Influence of the chytrid fungus on cutaneous water permeability of anuran amphibians2014

    • Author(s)
      Yuki Shibata, Sho Kadekaru, Toshihiro Tokiwa, Yumi Une, Masakazu Suzuki
    • Organizer
      ELSU symposium 2014
    • Place of Presentation
      B-Nest、静岡
    • Year and Date
      2014-09-29 – 2014-09-30
    • Related Report
      2014 Research-status Report
  • [Presentation] 有尾両生類における腹側皮膚型アクアポリン(AQPa2S)の機能と分子進化2014

    • Author(s)
      柴田侑毅, Stanley D Hillyard, 岡田令子, 鈴木雅一,長井孝紀
    • Organizer
      第85回日本動物学会大会
    • Place of Presentation
      東北大学川内北キャンパス、仙台
    • Year and Date
      2014-09-11 – 2014-09-13
    • Related Report
      2014 Research-status Report
  • [Book] ホルモンから見た生命現象と進化シリーズ 第5巻 ホメオスタシスと適応-恒- 第7章 皮膚2016

    • Author(s)
      鈴木 雅一
    • Publisher
      裳華房
    • Related Report
      2016 Annual Research Report
  • [Book] ホルモンから見た生命現象と進化シリーズ 第5巻 ホメオスタシスと適応-恒-2016

    • Author(s)
      鈴木 雅一(共著)
    • Publisher
      裳華房
    • Related Report
      2015 Research-status Report
  • [Book] 動物の事典2016

    • Author(s)
      鈴木 雅一(共著)
    • Publisher
      朝倉書店
    • Related Report
      2015 Research-status Report
  • [Book] Advances in Animal Science and Zoology2015

    • Author(s)
      Yuki Shibata & Masakazu Suzuki
    • Total Pages
      172
    • Publisher
      Nova Science Publishers
    • Related Report
      2015 Research-status Report
  • [Book] 動物の事典 9.5.5甲状腺2015

    • Author(s)
      鈴木 雅一
    • Publisher
      朝倉書店
    • Related Report
      2014 Research-status Report
  • [Book] 動物の事典 9.5.6副甲状腺・鰓後腺・甲状腺傍濾胞細胞2015

    • Author(s)
      鈴木 雅一
    • Publisher
      朝倉書店
    • Related Report
      2014 Research-status Report

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Published: 2014-04-04   Modified: 2022-12-28  

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